A workshop dedicated to the presentation of the in meso in situ serial crystallography (IMISX) method (Huang et al. 2015, 2016 ActaD) for the X-ray structure determination of membrane proteins is organised at the Swiss Light Source at PSI for the second time. It will be held between November 27 and 29, 2017. The workshop consists of introductory lectures, as well as presentations of serial crystallography activities at various synchrotron facilities. The main part of the workshop focus on hands-on practicals on methods for growing crystals of membrane proteins by the in meso or LCP method, for collecting serial diffraction data on micro-crystals directly in situ and for processing the data most efficiently for high-resolution structure determination.