2024
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Corpetti M, Müller C, Beltran H, de Bono J, Theurillat JP
Prostate-specific membrane antigen–targeted therapies for prostate cancer: towards improving therapeutic outcomes
European Urology. 2024; 85(3): 193-204. https://doi.org/10.1016/j.eururo.2023.11.018
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Favaretto C, Grundler PV, Talip Z, Köster U, Johnston K, Busslinger SD, et al.
Terbium-149 production: a focus on yield and quality improvement towards preclinical application
Scientific Reports. 2024; 14(1): 3284 (12 pp.). https://doi.org/10.1038/s41598-024-53610-2
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Fricke J, Westerbergh F, McDougall L, Favaretto C, Christ E, Nicolas GP, et al.
First-in-human administration of terbium-161-labelled somatostatin receptor subtype 2 antagonist ([161Tb]Tb-DOTA-LM3) in a patient with a metastatic neuroendocrine tumour of the ileum
European Journal of Nuclear Medicine and Molecular Imaging. 2024; 51: 2517-2519. https://doi.org/10.1007/s00259-024-06641-w
DORA PSI -
Gomes CV, Mendes BM, Paixão L, Gnesin S, Müller C, van der Meulen NP, et al.
Comparison of the dosimetry of scandium-43 and scandium-44 patient organ doses in relation to commonly used gallium-68 for imaging neuroendocrine tumours
EJNMMI Physics. 2024; 11(1): 61 (14 pp.). https://doi.org/10.1186/s40658-024-00669-5
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Gutmann M, Reinhardt D, Seidensticker C, Raschig M, Hahn L, Moscaroli A, et al.
Matrix metalloproteinase-responsive delivery of PEGylated fibroblast growth factor 2
ACS Biomaterials Science & Engineering. 2024; 10(1): 156-165. https://doi.org/10.1021/acsbiomaterials.3c01511
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Holzleitner N, Cwojdzinski T, Beck R, Urtz-Urban N, Hillhouse CC, Grundler PV, et al.
Preclinical evaluation of gastrin-releasing peptide receptor antagonists labeled with 161Tb and 177Lu: a comparative study
Journal of Nuclear Medicine. 2024; 65(3): 481-484. https://doi.org/10.2967/jnumed.123.266233
DORA PSI -
Mizuno R, Niikura M, Saito TY, Matsuzaki T, Sakurai H, Amato A, et al.
Development of wide range photon detection system for muonic X-ray spectroscopy
Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2024; 1060: 169029 (14 pp.). https://doi.org/10.1016/j.nima.2023.169029
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Rottenburger C, Hentschel M, Fürstner M, McDougall L, Kottoros D, Kaul F, et al.
In-vivo inhibition of neutral endopeptidase 1 results in higher absorbed tumor doses of [177Lu]Lu-PP-F11N in humans: the lumed phase 0b study
EJNMMI Research. 2024; 14(1): 37 (13 pp.). https://doi.org/10.1186/s13550-024-01101-w
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Sarogni P, Brindani N, Zamborlin A, Gonnelli A, Menicagli M, Mapanao AK, et al.
Tumor growth-arrest effect of tetrahydroquinazoline-derivative human topoisomerase II-alpha inhibitor in HPV-negative head and neck squamous cell carcinoma
Scientific Reports. 2024; 14(1): 9150 (10 pp.). https://doi.org/10.1038/s41598-024-59592-5
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Song Y, Zou J, Castellanos EA, Matsuura N, Ronald JA, Shuhendler A, et al.
Theranostics - a sure cure for cancer after 100 years?
Theranostics. 2024; 14(6): 2464-2488. https://doi.org/10.7150/thno.96675
DORA PSI -
Tagliente G, Milazzo PM, Paradela C, Kopecky S, Vescovi D, Alaerts G, et al.
High-resolution cross section measurements for neutron interactions on 89Y with incident neutron energies up to 95 keV
European Physical Journal A: Hadrons and Nuclei. 2024; 60(1): 21 (18 pp.). https://doi.org/10.1140/epja/s10050-024-01243-4
DORA PSI -
Trachsel B, Imobersteg S, Valpreda G, Singer G, Grabherr R, Ormos M, et al.
Relaxed fibronectin: a potential novel target for imaging endometriotic lesions
EJNMMI Research. 2024; 14(1): 17 (11 pp.). https://doi.org/10.1186/s13550-024-01070-0
DORA PSI -
Vaccarin C, Mapanao AK, Deberle LM, Becker AE, Borgna F, Marzaro G, et al.
Design and preclinical evaluation of a novel prostate-specific membrane antigen radioligand modified with a transthyretin binder
Cancers. 2024; 16(7): 1262 (13 pp.). https://doi.org/10.3390/cancers16071262
DORA PSI -
Vaccarin C, Veit G, Hegedus T, Torres O, Chilin A, Lukacs GL, et al.
Synthesis and biological evaluation of pyrazole-pyrimidones as a new class of correctors of the cystic fibrosis transmembrane conductance regulator (CFTR)
Journal of Medicinal Chemistry. 2024. https://doi.org/10.1021/acs.jmedchem.4c00685
DORA PSI -
Wallimann RH, Hensinger H, Müller C, Schibli R, Kneuer R, Schindler P
Liquid chromatography ICP-MS to assess the stability of 175Lu- and natGa-based tumor-targeting agents towards the development of 177Lu- and 68Ga-labeled radiopharmaceuticals
Pharmaceutics. 2024; 16(3): 299 (13 pp.). https://doi.org/10.3390/pharmaceutics16030299
DORA PSI -
de Roode KE, Joosten L, Behe M
Towards the magic radioactive bullet: improving targeted radionuclide therapy by reducing the renal retention of radioligands
Pharmaceuticals. 2024; 17(2): 256 (31 pp.). https://doi.org/10.3390/ph17020256
DORA PSI
2023
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Alcayne V, Mendoza E, Cano-Ott D, Kimura A, Aberle O, Amaducci S, et al.
Results of the 244Cm, 246Cm and 248Cm neutron-induced capture cross sections measurements at EAR1 and EAR2 of the n_TOF facility
In: Mattoon CM, Vogt R, Escher J, Thompson I, eds. 15th international conference on nuclear data for science and technology (ND2022). Vol. 284. EPJ web conferences. Les Ulis Cedex A: EDP Sciences; 2023:01009 (6 pp.). https://doi.org/10.1051/epjconf/202328401009
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Beyer D, Vaccarin C, Deupi X, Mapanao AK, Cohrs S, Sozzi-Guo F, et al.
A tool for nuclear imaging of the SARS-CoV-2 entry receptor: molecular model and preclinical development of ACE2-selective radiopeptides
EJNMMI Research. 2023; 13(1): 32 (14 pp.). https://doi.org/10.1186/s13550-023-00979-2
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Biswas S, Megatli-Niebel I, Raselli L, Simke R, Cocolios TE, Deokar N, et al.
The non-destructive investigation of a late antique knob bow fibula (Bügelknopffibel) from Kaiseraugst/CH using Muon Induced X-ray Emission (MIXE)
Heritage Science. 2023; 11: 43 (17 pp.). https://doi.org/10.1186/s40494-023-00880-0
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Busslinger SD, Becker AE, Vaccarin C, Deberle LM, Renz M-L, Groehn V, et al.
Investigations using albumin binders to modify the tissue distribution profile of radiopharmaceuticals exemplified with folate radioconjugates
Cancers. 2023; 15(17): 4259 (19 pp.). https://doi.org/10.3390/cancers15174259
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Chen K, Mackiewicz A, Virtanen S, Grundler PV, Seifert H-P, Ritter S
Effect of zinc injection on mitigating stress corrosion cracking initiation of structural materials in light water reactor primary water
Corrosion Reviews. 2023; 41(3): 387-398. https://doi.org/10.1515/corrrev-2022-0098
DORA PSI -
Chiera NM, Dressler R, Sprung P, Talip Z, Schumann D
Determination of the half-life of gadolinium-148
Applied Radiation and Isotopes. 2023; 194: 110708 (5 pp.). https://doi.org/10.1016/j.apradiso.2023.110708
DORA PSI -
Dellepiane G, Casolaro P, Favaretto C, Gottstein A, Grundler PV, Mateu I, et al.
Cross-section measurement of thulium radioisotopes with an 18 MeV medical PET cyclotron for an optimized 165Er production
Applied Radiation and Isotopes. 2023; 200: 110954 (11 pp.). https://doi.org/10.1016/j.apradiso.2023.110954
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Ermini ML, Summa M, Zamborlin A, Frusca V, Mapanao AK, Mugnaioli E, et al.
Copper nano-architecture topical cream for the accelerated recovery of burnt skin
Nanoscale Advances. 2023; 5(4): 1212-1219. https://doi.org/10.1039/d2na00786j
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Favaretto C, Grundler PV, Talip Z, Landolt S, Sepini L, Köster U, et al.
161Tb-DOTATOC production using a fully automated disposable cassette system: a first step toward the introduction of 161Tb into the clinic
Journal of Nuclear Medicine. 2023; 64(7): 1138-1144. https://doi.org/10.2967/jnumed.122.265268
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Grzmil M, Wiesmann F, Schibli R, Behe M
Targeting mTORC1 activity to improve efficacy of radioligand therapy in cancer
Cancers. 2023; 15(1): 17 (12 pp.). https://doi.org/10.3390/cancers15010017
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Happl B, Brandt M, Balber T, Benčurová K, Talip Z, Voegele A, et al.
Synthesis and preclinical evaluation of radiolabeled [103Ru]BOLD-100
Pharmaceutics. 2023; 15(11): 2626 (11 pp.). https://doi.org/10.3390/pharmaceutics15112626
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Hofmann BA, Bolliger Schreyer S, Biswas S, Gerchow L, Wiebe D, Schumann M, et al.
An arrowhead made of meteoritic iron from the late Bronze Age settlement of Mörigen, Switzerland and its possible source
Journal of Archaeological Science. 2023; 157: 105827 (10 pp.). https://doi.org/10.1016/j.jas.2023.105827
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Juget F, Durán T, Nedjadi Y, Talip Z, Grundler PV, Favaretto C, et al.
Activity measurement of 44Sc and calibration of activity measurement instruments on production sites and clinics
Molecules. 2023; 28(3): 1345 (10 pp.). https://doi.org/10.3390/molecules28031345
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Kiss OC, Scott PJH, Behe M, Penuelas I, Passchier J, Rey A, et al.
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
EJNMMI Radiopharmacy and Chemistry. 2023; 8(1): 6 (18 pp.). https://doi.org/10.1186/s41181-023-00192-5
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Müller C, van der Meulen NP, Schibli R
Opportunities and potential challenges of using terbium-161 for targeted radionuclide therapy in clinics
European Journal of Nuclear Medicine and Molecular Imaging. 2023; 50: 3181-3184. https://doi.org/10.1007/s00259-023-06316-y
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Pekeč T, Venkatachalapathy S, Shim AR, Paysan D, Grzmil M, Schibli R, et al.
Detecting radio- and chemoresistant cells in 3D cancer co-cultures using chromatin biomarkers
Scientific Reports. 2023; 13(1): 20662 (14 pp.). https://doi.org/10.1038/s41598-023-47287-2
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Qin Y, Imobersteg S, Frank S, Blanc A, Chiorazzo T, Berger P, et al.
Signaling network response to α-particle–targeted therapy with the 225Ac-labeled minigastrin analog 225Ac-PP-F11N reveals the radiosensitizing potential of histone deacetylase inhibitors
Journal of Nuclear Medicine. 2023; 64(6): 873-879. https://doi.org/10.2967/jnumed.122.264597
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Radzina M, Saule L, Mamis E, Koester U, Cocolios TE, Pajuste E, et al.
Novel radionuclides for use in nuclear medicine in Europe: where do we stand and where do we go?
EJNMMI Radiopharmacy and Chemistry. 2023; 8(1): 27 (16 pp.). https://doi.org/10.1186/s41181-023-00211-5
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Renaldin E, Dellepiane G, Braccini S, Sommerhalder A, Zhang H, van der Meulen NP, et al.
Study of thulium-167 cyclotron production: a potential medically-relevant radionuclide
Frontiers in Chemistry. 2023; 11: 1288588 (14 pp.). https://doi.org/10.3389/fchem.2023.1288588
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Ritter S, Grundler PV, Rowthu S
A decade of research on noble metal chemical addition at PSI – lessons learned
In: International conference on water chemistry in nuclear reactor systems (NPC 2023). France: Sfen; 2023:(12 pp.).
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Sarogni P, Zamborlin A, Mapanao AK, Logghe T, Brancato L, van Zwol E, et al.
Hyperthermia reduces irradiation-induced tumor repopulation in an in vivo pancreatic carcinoma model
Advanced biology. 2023; 7(10): 2200229 (9 pp.). https://doi.org/10.1002/adbi.202200229
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Sosnin NV, Lederer-Woods C, Krtička M, Garg R, Dietz M, Bacak M, et al.
Measurement of the 77Se (n, γ) cross section up to 200 keV at the n_TOF facility at CERN
Physical Review C: Nuclear Physics. 2023; 107(6): 065805 (9 pp.). https://doi.org/10.1103/PhysRevC.107.065805
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Torres-Sánchez P, Praena J, Porras I, Sabaté-Gilarte M, Lederer-Woods C, Aberle O, et al.
Measurement of the 14N(n, p) 14C cross section at the CERN n_TOF facility from subthermal energy to 800 keV
Physical Review C: Nuclear Physics. 2023; 107(6): 064617 (15 pp.). https://doi.org/10.1103/PhysRevC.107.064617
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Trachsel B, Valpreda G, Lutz A, Schibli R, Mu L, Béhé M
Reducing kidney uptake of radiolabelled exendin-4 using variants of the renally cleavable linker MVK
EJNMMI Radiopharmacy and Chemistry. 2023; 8(1): 21 (11 pp.). https://doi.org/10.1186/s41181-023-00206-2
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Tschan VJ, Busslinger SD, Bernhardt P, Grundler PV, Zeevaart JR, Köster U, et al.
Albumin-binding and conventional PSMA ligands in combination with 161Tb: biodistribution, dosimetry, and preclinical therapy
Journal of Nuclear Medicine. 2023; 64(10): 1625-1631. https://doi.org/10.2967/jnumed.123.265524
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Wallimann RH, Schindler P, Hensinger H, Tschan VJ, Busslinger SD, Kneuer R, et al.
Inductively coupled plasma mass spectrometry - a valid method for the characterization of metal conjugates in view of the development of radiopharmaceuticals
Molecular Pharmaceutics. 2023; 20(4): 2150-2158. https://doi.org/10.1021/acs.molpharmaceut.2c01092
DORA PSI
2022
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Benešová M, Guzik P, Deberle LM, Busslinger SD, Landolt T, Schibli R, et al.
Design and evaluation of novel albumin-binding folate radioconjugates: systematic approach of varying the linker entities
Molecular Pharmaceutics. 2022; 19: 963-973. https://doi.org/10.1021/acs.molpharmaceut.1c00932
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Borgna F, Haller S, Monné Rodriguez JM, Ginj M, Grundler PV, Zeevaart JR, et al.
Combination of terbium-161 with somatostatin receptor antagonists - a potential paradigm shift for the treatment of neuroendocrine neoplasms
European Journal of Nuclear Medicine and Molecular Imaging. 2022; 49: 1113-1126. https://doi.org/10.1007/s00259-021-05564-0
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Borgna F, Deberle LM, Busslinger SD, Tschan VJ, Walde LM, Becker AE, et al.
Preclinical investigations to explore the difference between the diastereomers [177Lu]Lu-SibuDAB and [177Lu]Lu-RibuDAB toward prostate cancer therapy
Molecular Pharmaceutics. 2022; 19(7): 2105-2114. https://doi.org/10.1021/acs.molpharmaceut.1c00994
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Braccini S, Carzaniga TS, Dellepiane G, Grundler PV, Scampoli P, van der Meulen NP, et al.
Optimization of 68Ga production at an 18 MeV medical cyclotron with solid targets by means of cross-section measurement of 66Ga, 67Ga and 68Ga
Applied Radiation and Isotopes. 2022; 186: 110252 (9 pp.). https://doi.org/10.1016/j.apradiso.2022.110252
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Busslinger SD, Tschan VJ, Richard OK, Talip Z, Schibli R, Müller C
[225Ac]Ac-SibuDAB for targeted alpha therapy of prostate cancer: preclinical evaluation and comparison with [225Ac]Ac-PSMA-617
Cancers. 2022; 14(22): 5651 (16 pp.). https://doi.org/10.3390/cancers14225651
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Che PP, Mapanao AK, Gregori A, Ermini ML, Zamborlin A, Capula M, et al.
Biodegradable ultrasmall-in-nano architectures loaded with cisplatin prodrug in combination with ionizing radiation induces DNA damage and apoptosis in pancreatic ductal adenocarcinoma
Cancers. 2022; 14(12): 3034 (17 pp.). https://doi.org/10.3390/cancers14123034
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Chiera NM, Dressler R, Sprung P, Talip Z, Schumann D
High precision half-life measurement of the extinct radio-lanthanide Dysprosium-154
Scientific Reports. 2022; 12(1): 8988 (10 pp.). https://doi.org/10.1038/s41598-022-12684-6
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Dellepiane G, Casolaro P, Favaretto C, Grundler PV, Mateu I, Scampoli P, et al.
Cross section measurement of terbium radioisotopes for an optimized 155Tb production with an 18 MeV medical PET cyclotron
Applied Radiation and Isotopes. 2022; 184: 110175 (14 pp.). https://doi.org/10.1016/j.apradiso.2022.110175
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Di Liddo R, Verona M, Vaccarin C, Acquasaliente L, Schrenk S, Piccione M, et al.
Preliminary discovery of small molecule inhibitors of Epidermal Growth Factor Receptor (EGFR) that bind to the extracellular domain
Cancers. 2022; 14(15): 3647 (22 pp.). https://doi.org/10.3390/cancers14153647
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Durán MT, Juget F, Nedjadi Y, Bailat C, Grundler PV, Talip Z, et al.
Half-life measurement of 44Sc and 44mSc
Applied Radiation and Isotopes. 2022; 190: 110507 (10 pp.). https://doi.org/10.1016/j.apradiso.2022.110507
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Eichler R, Kiselev D, Koschik A, Knecht A, van der Meulen N, Scheibl R, et al.
IMPACT conceptual design report
Villigen PSI: Paul Scherrer Institut; 2022. PSI Bericht: 22-01.
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Franceschinis E, Roverso M, Gabbia D, De Martin S, Brusegan M, Vaccarin C, et al.
Self-emulsifying formulations to increase the oral bioavailability of 4,6,4′-trimethylangelicin as a possible treatment for cystic fibrosis
Pharmaceutics. 2022; 14(9): 1806. https://doi.org/10.3390/pharmaceutics14091806
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Gillings N, Hjelstuen O, Behe M, Decristoforo C, Elsinga PH, Ferrari V, et al.
EANM guideline on quality risk management for radiopharmaceuticals
European Journal of Nuclear Medicine and Molecular Imaging. 2022; 49: 3353-3364. https://doi.org/10.1007/s00259-022-05738-4
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Grzmil M, Boersema P, Sharma A, Blanc A, Imobersteg S, Pruschy M, et al.
Comparative analysis of cancer cell responses to targeted radionuclide therapy (TRT) and external beam radiotherapy (EBRT)
Journal of Hematology & Oncology. 2022; 15(1): 123 (5 pp.). https://doi.org/10.1186/s13045-022-01343-y
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Hemmingsson J, Svensson J, van der Meulen NP, Müller C, Bernhardt P
Active bone marrow S-values for the low-energy electron emitter terbium-161 compared to S-values for lutetium-177 and yttrium-90
EJNMMI Physics. 2022; 9(1): 65 (13 pp.). https://doi.org/10.1186/s40658-022-00495-7
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Juget F, Talip Z, Nedjadi Y, Durán MT, Grundler PV, Zeevaart JR, et al.
Precise activity measurements of medical radionuclides using an ionization chamber: a case study with Terbium-161
EJNMMI Physics. 2022; 9(1): 19 (18 pp.). https://doi.org/10.1186/s40658-022-00448-0
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Miller IS, Khan S, Shiels LP, Das S, O' Farrell AC, Connor K, et al.
Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects
Cancer Medicine. 2022; 11(20): 3820-3836. https://doi.org/10.1002/cam4.4756
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Rigamonti N, Veitonmäki N, Domke C, Barsin S, Jetzer S, Abdelmotaleb O, et al.
A multispecific anti-CD40 DARPin construct induces tumor-selective CD40 activation and tumor regression
Cancer Immunology Research. 2022; 10(5): 626-640. https://doi.org/10.1158/2326-6066.CIR-21-0553
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Schmitt J, Schwenck J, Maurer A, Przybille M, Sonanini D, Reischl G, et al.
Translational immunoPET imaging using a radiolabeled GD2-specific antibody in neuroblastoma
Theranostics. 2022; 12(13): 5615-5630. https://doi.org/10.7150/thno.56736
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Schwenck J, Maurer A, Beziere N, Fiz F, Boschetti F, Geistlich S, et al.
Antibody-guided molecular imaging of Aspergillus lung infections in leukemia patients
Journal of Nuclear Medicine. 2022; 63(9): 1450-1451. https://doi.org/10.2967/jnumed.121.263251
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Tosato M, Verona M, Favaretto C, Pometti M, Zanoni G, Scopelliti F, et al.
Chelation of theranostic copper radioisotopes with S-rich macrocycles: from radiolabelling of copper-64 to in vivo investigation
Molecules. 2022; 27(13): 4158 (19 pp.). https://doi.org/10.3390/molecules27134158
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Trebosc V, Lucchini V, Narwal M, Wicki B, Gartenmann S, Schellhorn B, et al.
Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis
Virulence. 2022; 13(1): 1868-1883. https://doi.org/10.1080/21505594.2022.2135273
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Tschan VJ, Borgna F, Schibli R, Müller C
Impact of the mouse model and molar amount of injected ligand on the tissue distribution profile of PSMA radioligands
European Journal of Nuclear Medicine and Molecular Imaging. 2022; 49: 470-480. https://doi.org/10.1007/s00259-021-05446-5
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Tschan VJ, Borgna F, Busslinger SD, Stirn M, Monné Rodriguez JM, Bernhardt P, et al.
Preclinical investigations using [177Lu]Lu-Ibu-DAB-PSMA toward its clinical translation for radioligand therapy of prostate cancer
European Journal of Nuclear Medicine and Molecular Imaging. 2022; 49: 3639-3650. https://doi.org/10.1007/s00259-022-05837-2
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Tupini C, Chilin A, Rossi A, De Fino I, Bragonzi A, D’Aversa E, et al.
New TMA (4,6,4′-trimethyl angelicin) analogues as anti-inflammatory agents in the treatment of cystic fibrosis lung disease
International Journal of Molecular Sciences. 2022; 23(22): 14483 (20 pp.). https://doi.org/10.3390/ijms232214483
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Vaccarin C, Gabbia D, Franceschinis E, De Martin S, Roverso M, Bogialli S, et al.
Improved trimethylangelicin analogs for cystic fibrosis: design, synthesis and preliminary screening
International Journal of Molecular Sciences. 2022; 23(19): 11528 (14 pp.). https://doi.org/10.3390/ijms231911528
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Valpreda G, Trachsel B, Vogel V, Schibli R, Mu L, Behe M
Dual MVK cleavable linkers effectively reduce renal retention of 111In-fibronectin-binding peptides
Bioorganic and Medicinal Chemistry. 2022; 73: 117040 (11 pp.). https://doi.org/10.1016/j.bmc.2022.117040
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Zippel C, Ermert J, Patt M, Gildehaus FJ, Ross TL, Reischl G, et al.
Cyclotrons operated for nuclear medicine and radiopharmacy in the German Speaking D-A-CH countries: an update on current status and trends
Frontiers in Nuclear Medicine. 2022; 2: 850414 (10 pp.). https://doi.org/10.3389/fnume.2022.850414
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2021
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Aime S, Al-Qahtani M, Behe M, Bormans G, Carlucci G, DaSilva JN, et al.
Highlight selection of radiochemistry and radiopharmacy developments by editorial board
EJNMMI Radiopharmacy and Chemistry. 2021; 6(1): 13 (19 pp.). https://doi.org/10.1186/s41181-021-00128-x
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Al-Qahtani M, Behe M, Bormans G, Carlucci G, Dasilva J, Decristoforo C, et al.
Highlight selection of radiochemistry and radiopharmacy developments by editorial board (January-June 2020)
EJNMMI Radiopharmacy and Chemistry. 2021; 6(1): 5 (13 pp.). https://doi.org/10.1186/s41181-020-00118-5
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Baum RP, Singh A, Kulkarni HR, Bernhardt P, Rydén T, Schuchardt C, et al.
First-in-human application of terbium-161: a feasibility study using 161Tb-DOTATOC
Journal of Nuclear Medicine. 2021; 62(10): 1391-1397. https://doi.org/10.2967/jnumed.120.258376
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Bernhardt P, Svensson J, Hemmingsson J, van der Meulen NP, Zeevaart JR, Konijnenberg MW, et al.
Dosimetric analysis of the short-ranged particle emitter 161Tb for radionuclide therapy of metastatic prostate cancer
Cancers. 2021; 13(9): 2011 (13 pp.). https://doi.org/10.3390/cancers13092011
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Borgna F, Barritt P, Grundler PV, Talip Z, Cohrs S, Zeevaart JR, et al.
Simultaneous visualization of 161Tb-and 177Lu-labeled somatostatin analogues using dual-isotope SPECT imaging
Pharmaceutics. 2021; 13(4): 536 (13 pp.). https://doi.org/10.3390/pharmaceutics13040536
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Deberle LM, Benešová M, Becker AE, Ratz M, Guzik P, Schibli R, et al.
Novel synthetic strategies enable the efficient development of folate conjugates for cancer radiotheranostics
Bioconjugate Chemistry. 2021; 32(8): 1617-1628. https://doi.org/10.1021/acs.bioconjchem.1c00198
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Duchemin C, Ramos JP, Stora T, Ahmed E, Aubert E, Audouin N, et al.
CERN-MEDICIS: a review since commissioning in 2017
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Kaeppeli SAM, Schibli R, Mindt TL, Behe M
Comparison of desferrioxamine and NODAGA for the gallium-68 labeling of exendin-4
EJNMMI Radiopharmacy and Chemistry. 2019; 4(1): 9 (11 pp.). https://doi.org/10.1186/s41181-019-0060-9
DORA PSI -
Kaeppeli SAM, Jodal A, Gotthardt M, Schibli R, Behe M
Exendin-4 derivatives with an albumin-binding moiety show decreased renal retention and improved GLP-1 receptor targeting
Molecular Pharmaceutics. 2019; 16(9): 3760-3769. https://doi.org/10.1021/acs.molpharmaceut.9b00271
DORA PSI -
Kranzbühler B, Salemi S, Umbricht CA, Deberle LM, Müller C, Burger IA, et al.
Concentration‐dependent effects of dutasteride on prostate‐specific membrane antigen (PSMA) expression and uptake of 177Lu‐PSMA‐617 in LNCaP cells
Prostate. 2019; 79(12): 1477-1483. https://doi.org/10.1002/pros.23868
DORA PSI -
Müller C, De Prado Leal M, Dominietto MD, Umbricht CA, Safai S, Perrin RL, et al.
Combination of proton therapy and radionuclide therapy in mice: preclinical pilot sudy at the Paul Scherrer Institute
Pharmaceutics. 2019; 11(9): 450 (13 pp.). https://doi.org/10.3390/pharmaceutics11090450
DORA PSI -
Müller C, Singh A, Umbricht CA, Kulkarni HR, Johnston K, Benešová M, et al.
Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer
EJNMMI Research. 2019; 9(1): 68 (10 pp.). https://doi.org/10.1186/s13550-019-0538-1
DORA PSI -
Müller C, Umbricht CA, Gracheva N, Tschan VJ, Pellegrini G, Bernhardt P, et al.
Terbium-161 for PSMA-targeted radionuclide therapy of prostate cancer
European Journal of Nuclear Medicine and Molecular Imaging. 2019; 46(9): 1919-1930. https://doi.org/10.1007/s00259-019-04345-0
DORA PSI -
Pretze M, van der Meulen N P, Wängler C, Schibli R, Wängler B
Targeted 64Cu-labeled gold nanoparticles for dual imaging with positron emission tomography and optical imaging
Journal of Labelled Compounds and Radiopharmaceuticals. 2019; 62(8): 471-482. https://doi.org/10.1002/jlcr.3736
DORA PSI -
Radford LL, Fernandez S, Beacham R, Sayed RE, Farkas R, Benešová M, et al.
New 55Co-labeled albumin-binding folate derivatives as potential PET agents for folate receptor imaging
Pharmaceuticals. 2019; 12(4): 166 (12 pp.). https://doi.org/10.3390/ph12040166
DORA PSI -
Ritler A, Shoshan MS, Deupi X, Wilhelm P, Schibli R, Wennemers H, et al.
Elucidating the structure−activity relationship of the pentaglutamic acid sequence of minigastrin with cholecystokinin receptor subtype 2
Bioconjugate Chemistry. 2019; 30(3): 657-666. https://doi.org/10.1021/acs.bioconjchem.8b00849
DORA PSI -
Ritter S, Grundler PV, Rowthu S
Assessment of the SCC mitigation capabilities of the NobleChemTM technology in simulated BWR environment
Presented at: ICG-EAC Annual Meeting 2019; May 12-17, 2019; Tainan, Taiwan.
DORA PSI -
Rowthu S, Yeh Y-W, Grundler PV, Holmes R, Ritter S
Assessment of the Pt nanoparticle distribution on oxidized stainless steel surfaces by electrochemical techniques
Presented at: EUROCORR 2019; September 9-13, 2019; Seville, Spain.
DORA PSI -
Rupp NJ, Umbricht CA, Pizzuto DA, Lenggenhager D, Töpfer A, Müller J, et al.
First clinico-pathological evidence of a non PSMA-related uptake mechanism for 68Ga-PSMA-11 in salivary glands
Journal of Nuclear Medicine. 2019; 60(9): 1270-1276. https://doi.org/10.2967/jnumed.118.222307
DORA PSI -
Schniering J, Benešová M, Brunner M, Haller S, Cohrs S, Frauenfelder T, et al.
18F-AzaFol for detection of folate receptor-β positive macrophages in experimental interstitial lung disease - a proof-of-concept study
Frontiers in Immunology. 2019; 10: 2724 (15 pp.). https://doi.org/10.3389/fimmu.2019.02724
DORA PSI -
Siwowska K, Guzik P, Domnanich KA, Monné Rodríguez JM, Bernhardt P, Ponsard B, et al.
Therapeutic potential of 47Sc in comparison to 177Lu and 90Y: preclinical investigations
Pharmaceutics. 2019; 11(8): 424 (13 pp.). https://doi.org/10.3390/pharmaceutics11080424
DORA PSI -
Umbricht CA, Köster U, Bernhardt P, Gracheva N, Johnston K, Schibli R, et al.
Alpha-PET for prostate cancer: preclinical investigation using 149Tb-PSMA-617
Scientific Reports. 2019; 9: 17800 (10 pp.). https://doi.org/10.1038/s41598-019-54150-w
DORA PSI -
Zhang J, Singh A, Kulkarni HR, Schuchardt C, Müller D, Wester H-J, et al.
From bench to bedside—the Bad Berka experience with first-in-human studies
Seminars in Nuclear Medicine. 2019; 49(5): 422-437. https://doi.org/10.1053/j.semnuclmed.2019.06.002
DORA PSI -
van der Meulen NP, Hasler R, Blanc A, Farkas R, Benešová M, Talip Z, et al.
Implementation of a new separation method to produce qualitatively improved 64Cu
Journal of Labelled Compounds and Radiopharmaceuticals. 2019; 62(8): 460-470. https://doi.org/10.1002/jlcr.3730
DORA PSI
2018
- Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2
ANNALS OF THE RHEUMATIC DISEASES , (2018).DOI: annrheumdis-2018-214322
- Design and Preclinical Evaluation of an Albumin-Binding PSMA Ligand for 64Cu-Based PET Imaging
MOLECULAR PHARMACEUTICS , (2018).DOI: acs.molpharmaceut.8b00712
- Metabotropic glutamate receptor subtype 5 is altered in LPS-induced murine neuroinflammation model and in the brains of AD and ALS patients
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING , (2018).DOI: s00259-018-4179-9
- In Vivo Labeling of Plasma Proteins for Imaging of Enhanced Vascular Permeability in the Lungs
MOLECULAR PHARMACEUTICS 15, 4995 (2018).DOI: acs.molpharmaceut.8b00606
- Combination of lutetium-177 labelled anti-L1CAM antibody chCE7 with the clinically relevant protein kinase inhibitor MK1775: a novel combination against human ovarian carcinoma
BMC CANCER 18, 922 (2018).DOI: s12885-018-4836-1
- Ketamine and Ceftriaxone-Induced Alterations in Glutamate Levels Do Not Impact the Specific Binding of Metabotropic Glutamate Receptor Subtype 5 Radioligand [18F]PSS232 in the Rat Brain
PHARMACEUTICASL (BASEL) E83, (2018).DOI: ph11030083
- Evaluation of 99mTc-rhAnnexin V-128 SPECT/CT as a diagnostic tool for early stages of interstitial lung disease associated with systemic sclerosis
ATHRITIS RESEARCH AND THERAPY 20, 183 (2018).DOI: s13075-018-1681-1
- Identification and Preclinical Evaluation of a Radiofluorinated Benzazepine Derivative for Imaging the GluN2B Subunit of the Ionotropic NMDA Receptor
JOURNAL OF NUCLEAR MEDICINE , (2018).DOI: jnumed.118.212134
- Physiologically Based Pharmacokinetic Modelling with Dynamic PET Data to Study the In Vivo Effects of Transporter Inhibition on Hepatobiliary Clearance in Mice
CONTRAST MEDIA AND MOLECULAR IMAGING 5849047, (2018).DOI: 5849047
- Unexpected reactivity of cyclic perfluorinated iodanes with electrophiles
CHEMICAL COMMUNICATIONS 54, 8999 (2018).DOI: c8cc04558e
- Diastereomerically Pure 6R- and 6S-3'-aza-2'-18F-Fluoro-5-Methyltetrahydrofolates Show Unprecedented High Uptake in Folate Receptor-positive KB Tumors
JOURNAL OF NUCLEAR MEDICINE , (2018).DOI: jnumed.118.213314
- Pharmacological upregulation of prostate-specific membrane antigen (PSMA) expression in prostate cancer cells
PROSTATE 78, 758 (2018).DOI: pros.23522
- Combining Albumin-Binding Properties and Interaction with Pemetrexed to Improve the Tissue Distribution of Radiofolates
MOLECULES 23, E1465 (2018).DOI: molecules23061465
- Scandium and terbium radionuclides for radiotheranostics: current state of development towards clinical application
BRITISH JOURNAL OF RADIOLOGY , (2018).DOI: bjr.20180074
- Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy
MOLECULAR PHARMACEUTICALS , (2018).DOI: acs.molpharmaceut.8b00152
- Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma
STEM CELL INTERNATIONAL 2018, 465850 (2018).DOI: 4658503
- Radiosynthesis and evaluation of an 18F-labeled silicon containing exendin-4 peptide as a PET probe for imaging insulinoma
EJNMMI RADIOPHARMACY AND CHEMISTRY 3, 1 (2018).DOI: s41181-017-0036-6
- Improved Syntheses of the Mglu₅ Antagonists MMPEP and MTEP Using Sonogashira Cross-Coupling
PHARMACEUTICALS (BASEL) 11, E24 (2018).DOI: ph11010024
- Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 145, 746 (2018).DOI: j.ejmech.2017.12.097
- Evaluation of 11C-Me-NB1 as a Potential PET Radioligand for Measuring GluN2B-Containing NMDA Receptors, Drug Occupancy, and Receptor Cross Talk
JOURNAL OF NUCLEAR MEDICINE 59, 698 (2018).DOI: jnumed.117.200451
- A first-in-man PET study of [18F]PSS232, a fluorinated ABP688 derivative for imaging metabotropic glutamate receptor subtype 5
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 45, 1041 (2018).DOI: s00259-017-3879-x
- Imaging of Folate Receptor Expressing Macrophages in the Rat Groove Model of Osteoarthritis: Using a New DOTA-Folate Conjugate
CARTILAGE 9, 183 (2018).DOI: 1947603517738073
- Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile
MOLECULAR PHARMACEUTICS 15, 934 (2018).DOI: acs.molpharmaceut.7b00877
- Reduced 18F-Folate Conjugates as a New Class of PET Tracers for Folate Receptor Imaging
BIOCONJUGATE CHEMISTRY 29, 1119 (2018).DOI: acs.bioconjchem.7b00775
2017
- Metabotropic glutamate receptor 5 binding in male patients with alcohol use disorder
TRANSLATIONAL PSYCHIATRY 8, 17 (2017).DOI: s41398-017-0066-6
- Imaging the glutamate receptor subtypes-Much achieved, and still much to do
DRUG DISCOVERY TODAY: TECHNOLOGIES 25, 27 (2017).DOI: j.ddtec.2017.10.006
- Radioligands for positron emission tomography imaging of cannabinoid type 2 receptor
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).DOI: jlcr.3579
- Cerebral mGluR5 availability contributes to elevated sleep need and behavioral adjustment after sleep deprivation
eLIFE , e28751 (2017).DOI: eLife.28751
- Novel peptide probes to assess the tensional state of fibronectin fibers in cancer
NATURE COMMUNICATIONS 8, 1793 (2017).DOI: s41467-017-01846-0
- Towards Translational ImmunoPET/MR Imaging of Invasive Pulmonary Aspergillosis: The Humanised Monoclonal Antibody JF5 Detects Aspergillus Lung Infections In Vivo
THERANOSTICS 7, 3398 (2017).DOI: thno.20919
- Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals
BIOCONJUGATE CHEMISTRY 28, 2372 (2017).DOI: acs.bioconjchem.7b00378
- Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters
JOURNAL OF NUCLEAR MEDICINE 58 (Suppl 2), 91S (2017).DOI: jnumed.116.186825
- Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC
DALTON TRANSACTION 46, 14638 (2017).DOI: c7dt01936j
- Folate Receptor-Positive Gynecological Cancer Cells: In Vitro and In Vivo Characterization
PHARMACEUTICALS (BASEL) 10, E72 (2017).DOI: ph10030072
- Dual, Site-Specific Modification of Antibodies by Using Solid-Phase Immobilized Microbial Transglutaminase
CHEMBIOCHEM 18, 1923 (2017).DOI: cbic.201700188
- A Short-Term Biological Indicator for Long-Term Kidney Damage after Radionuclide Therapy in Mice
PHARMACEUTICALS (BASEL) 10, E57 (2017).DOI: ph10020057
- First-in-Human PET/CT Imaging of Metastatic Neuroendocrine Neoplasms with Cyclotron-Produced 44Sc-DOTATOC: A Proof-of-Concept Study
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS 32, 124 (2017).DOI: cbr.2016.2173
- Radiolabeled 111In-FGF-2 Is Suitable for In Vitro/Ex Vivo Evaluations and In Vivo Imaging
MOLECULAR PHARMACEUTICS 14, 639 (2017).DOI: acs.molpharmaceut.6b0091
- Automated cGMP-compliant radiosynthesis of [18 F]-(E)-PSS232 for brain PET imaging of metabotropic glutamate receptor subtype 5
JOURNAL OF LABELLED COMPOUNDS AND RADIOPHARMACEUTICALS , (2017).DOI: jlcr.3566
- Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Early Skeletal Muscle Tissue Formation
CELL TRANSPLANTATION 26, 1103 (2017).DOI: 096368917X694868
- Kinetics of lipid bilayer permeation of a series of ionisable drugs and their correlation with human transporter-independent intestinal permeability
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 104, 150 (2017).DOI: j.ejps.2017.03.040
- GABAA receptor subtypes in the mouse brain: Regional mapping and diazepam receptor occupancy by in vivo [18F]flumazenil PET
NEUROIMAGE 15, 279 (2017).DOI: j.neuroimage.2017.02.022
- Cannabinoid receptor type 2 (CB2) as one of the candidate genes in human carotid plaque imaging: Evaluation of the novel radiotracer [11C]RS-016 targeting CB2 in atherosclerosis
NUCLEAR MEDICINE AND BIOLOGY 47, 31 (2017).DOI: j.nucmedbio.2017.01.001
- 44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617
EJNMMI RESEARCH 7, 9 (2017).DOI: s13550-017-0257-4
- Metabotropic glutamate receptor 5 neuroimaging in schizophrenia
SCHIZOPHRENIA RESEARCH 183, 95 (2017).DOI: j.schres.2016.11.008
- Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties
MOLECULAR PHARMACEUTICS 14, 523 (2017).DOI: acs.molpharmaceut.6b01010
- Methoxinine - an alternative stable amino acid substitute for oxidation-sensitive methionine in radiolabelled peptide conjugates
JOURNAL OF PEPTIDE SCIENCE 23, 38 (2017).DOI: psc.2948
- Targets and probes for non-invasive imaging of β-cells
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 44, 712 (2017).DOI: s00259-016-3592-1
2016
- 44Sc for labeling of DOTA- and NODAGA functionalized peptides: preclinical in vitro and in vivo investigations
EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).DOI: s41181-016-0013-5
- Alpha-PET with terbium-149: evidence and perspectives for radiotheragnostics
EJNMMI RADIOPHARMACY AND CHEMISTRY 1, 5 (2016).DOI: s41181-016-0008-2
- Preclinical in vivo application of (152)Tb-DOTANOC: a radiolanthanide for PET imaging
EJNMMI RESEARCH 6, 35 (2016).DOI: s13550-016-0189-4
- Evaluation of the first 44Sc-labeled Affibody molecule for imaging of HER2-expressing tumors
NUCLEAR MEDICINE AND BIOLOGY 45, 15 (2016).DOI: j.nucmedbio.2016.10.004
- Production of (28)Mg by bombardment of (nat)Cl with 200MeV protons: Proof-of-concept study for a stacked LiCl target
APPLIED RADIATION AND ISOTOPES 115, 125 (2016).DOI: j.apradiso.2016.04.026
- Enhanced sensitivity to drugs of abuse and palatable foods following maternal overnutrition
TRANSLATIONAL PSYCHIATRY 6, e911 (2016).DOI: tp.2016.176
- Synthesis and Pharmacological Evaluation of [11C]Granisetron and [18F]Fluoropalonosetron as PET Probes for 5-HT3 Receptor Imaging
ACS CHEMICAL NEUROSCIENCE 7, 1552 (2016).DOI: acschemneuro.6b00192
- Synthesis and Biological Evaluation of Thiophene-Based Cannabinoid Receptor Type 2 Radiotracers for PET Imaging
FRONTIERS IN NEUROSCIENCE 10, 350 (2016).DOI: fnins.2016.00350
- CD80 Is Upregulated in a Mouse Model with Shear Stress-Induced Atherosclerosis and Allows for Evaluating CD80-Targeting PET Tracers
MOLUCULAR IMAGING and BIOLOGY Epub ahead of print, (2016).DOI: s11307-016-0987-0
- Discovery of a Fluorinated 4-Oxo-Quinoline Derivative as a Potential PET Radiotracer for Imaging CB2 Receptor
JOURNAL OF NEUROCHEMISTRY 138, 874 (2016).DOI: jnc.13716
- Inhibition of MNK pathways enhances cancer cell response to chemotherapy with temozolomide and targeted radionuclide therapy
CELLULAR SIGNALLING 28, 1412 (2016).DOI: j.cellsig.2016.06.005
- Non-invasive Imaging and Tracking of Engineered Human Muscle Precursor Cells for Skeletal Muscle Tissue Engineering Using Positron Emission Tomography
JOURNAL OF NUCLEAR MEDICINE Epub ahead of print, (2016).DOI:
- Synthesis, Radiolabeling, and Biological Evaluation of 5-Hydroxy-2-[(18)F]fluoroalkyl-tryptophan Analogues as Potential PET Radiotracers for Tumor Imaging
JOURNAL OF MEDICINAL CHEMISTRY 59, 5324 (2016).DOI: acs.jmedchem.6b00057
- (64)Cu- and (68)Ga-Based PET Imaging of Folate Receptor-Positive Tumors: Development and Evaluation of an Albumin-Binding NODAGA-Folate
MOLECULAR PHARMACEUTICS 13, 1979 (2016).DOI: acs.molpharmaceut.6b00143
- Novel chemoselective (18)F-radiolabeling of thiol-containing biomolecules under mild aqueous conditions
CHEMICAL COMMUNICATION 52, 6083 (2016).DOI: c6cc01982j
- Contribution of Auger/conversion electrons to renal side effects after radionuclide therapy: preclinical comparison of (161)Tb-folate and (177)Lu-folate
EJNMMI RESEARCH 1, 13 (2016).DOI: s13550-016-0171-1
- ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivo
PNAS 113, E1026 (2016).DOI: pnas.1518836113
- Imaging quality of (44)Sc in comparison with five other PET radionuclides using Derenzo phantoms and preclinical PET
APPLIED RADIATION AND ISOTOPES 110, 129 (2016).DOI: j.apradiso.2016.01.006
- Preclinical imaging of the co-stimulatory molecules CD80 and CD86 with indium-111-labeled belatacept in atherosclerosis
EJNMMI RESEARCH 6, 1 (2016).DOI: s13550-015-0157-4
- Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18
BIOCONJUGATE CHEMISTRY 27, 74 (2016).DOI: acs.bioconjchem.5b00644
2015
- Ex vivo differential phase contrast and magnetic resonance imaging for characterization of human carotid atherosclerotic plaque
THE INTERNATIONAL JOURNAL OF CARDIOVASCULAR IMAGING 31, 1425 (2015).DOI: s10554-015-0706-y
- Folate receptor-targeted radionuclide therapy: preclinical investigation of anti-tumor effects and potential radionephropathy
NUCLEAR MEDICINE AND BIOLOGY 42, 770 (2015).DOI: j.nucmedbio.2015.06.006
- Cyclotron production of (44)Sc: From bench to bedside
NUCLEAR MEDICINE AND BIOLOGY 42, 745 (2015).DOI: j.nucmedbio.2015.05.00
- Longitudinal in vivo evaluation of bone regeneration by combined measurement of multi-pinhole SPECT and micro-CT for tissue engineering
SCIENTIFIC REPORTS 5, 10238 (2015).DOI: srep10238 Erratum DOI: srep12391
- Discovery of a high affinity and selective pyridine analog as a potential positron emission tomography imaging agent for cannabinoid type 2 receptor
JOURNAL OF MEDICINAL CHEMISTRY 58, 4266 (2015).DOI: acs.jmedchem.5b00283
- Evaluation of a Novel Tc-99m Labelled Vitamin B12 Derivative for Targeting Escherichia coli and Staphylococcus aureus In Vitro and in an Experimental Foreign-Body Infection Model
MOLECULAR IMAGING AND BIOLOGY 10, e0123443 (2015).DOI: s11307-015-0832-x
- Evaluation of ¹¹¹in-labelled exendin-4 derivatives containing different meprin β-specific cleavable linkers
PLOS ONE 10, e0123443 (2015).DOI: journal.pone.0123443
- Regional cerebral blood flow estimated by early PiB uptake is reduced in mild cognitive impairment and associated with age in an amyloid-dependent manner
NEUROBIOLOGY OF AGING 36, 1619 (2015).DOI: j.neurobiolaging.2014.12.036
- Microbial transglutaminase and c-myc-tag: a strong couple for the functionalization of antibody-like protein scaffolds from discovery platforms
CHEMBIOCHEM 16, 861 (2015).DOI: cbic.201500009
- Dosimetry and first clinical evaluation of the new 18F-radiolabeled bombesin analogue BAY 864367 in patients with prostate cancer
JOURNAL OF NUCLEAR MEDICINE 56, 372 (2015).DOI: jnumed.114.147116
- Synthesis and pharmacological evaluation of ¹¹C-labeled piperazine derivative as a PET probe for sigma-2 receptor imaging
NUCLEAR MEDICINE AND BIOLOGY 42, 399 (2015).DOI: j.nucmedbio.2014.12.018
- Evaluation of the radiolabeled boronic acid-based FAP inhibitor MIP-1232 for atherosclerotic plaque imaging
MOLUCULES 20, 2081 (2015).DOI: molecules20022081
- Investigation of the chick embryo as a potential alternative to the mouse for evaluation of radiopharmaceuticals
NUCLEAR MEDICINE AND BIOLOGY 42, 226 (2015).DOI: j.nucmedbio.2014.10.010
- Quantitative positron emission tomography of mGluR5 in rat brain with [(18) F]PSS232 at minimal invasiveness and reduced model complexity
JOURNAL OF NEUROCHEMISTRY 133, 330 (2015).DOI: jnc.13001
- Site-Specific Conjugation of Monomethyl Auristatin E to Anti-CD30 Antibodies Improves Their Pharmacokinetics and Therapeutic Index in Rodent Models
MOLECULAR PHARMACEUTICS 12, 1863 (2015).DOI: mp500666j
- Association of Long-Term Nicotine Abstinence with Normal Metabotropic Glutamate Receptor-5 Binding
BIOLOGYCAL PSYCHATRY , (2015).DOI: 10.1016/j.biopsych.2015.02.027
- Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 92, 554 (2015).DOI: j.ejmech.2015.01.028
- Folate Receptor-Targeted Multimodality Imaging of Ovarian Cancer in a Novel Syngeneic Mouse Model
MOLECULAR PHARMACEUTICS 12, 542 (2015).DOI: mp500628g
- Self-assembled gold coating enhances X-ray imaging of alginate microcapsules
NANOSCALE 7, 2480 (2015).DOI: c4nr06692h
- Excitation functions of natZr + p nuclear processes up to 70 MeV: New measurements and compilation
NUCLEAR INSTRUMENTS AND METHODS IN PHYSICS RESEARCH B 343, 173 (2015).DOI: j.nimb.2014.11.081
- Preclinical evaluation and test-retest studies of [(18)F]PSS232, a novel radioligand for targeting metabotropic glutamate receptor 5 (mGlu5)
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 42, 128 (2015).DOI: s00259-014-2883-7