Research Interests
My research is based on small-angle scattering (SAS) techniques, with a particular focus on characterizing the structure of soft matter systems with neutrons SANS and X-rays SAXS. So far, I've worked in different projects and groups with various types of soft materials, and my passion for SAS remains constant. During my exchanges between ETH (lecturer) and PSI (soft matter and beamline scientist), I have acquired expertise in performing and interpreting standard SAS measurements in diverse complex soft matter materials, as well as method development for in situ SAS measurements, such as the structural mapping of fluids under flow, imaging and tomographic techniques.
My research interests span a broad spectrum, for example hierarchical biomaterials (polysaccharide-based), self-assembled systems, and alternative routes for biopolymers and material characterization. Currently, I am co-responsible for the commissioning and user program of a new SANS-LLB instrument, which is shared among LLB (Saclay, France), and SINQ/PSI.
My current projects involve in situ SANS method development, mainly applied to soft matter under flow. These include the development of microfluidics platforms for SANS, chemical reactions under confinement and dark-field imaging.
Role | Organization | Duration |
| Tenure-Track Scientist | PSI Center for Neutrons and Muons, Soft Matter Group, Switzerland | 2021 - present |
| Visiting Scientist | Universidade Estadual de Campinas (UNICAMP), Brazil | 2023 |
| Senior Scientist | ETH Zürich, Laboratory of Food and Soft Materials Science, Switzerland | 2019-2021 |
| PostDoc | PSI Center for Photon Science, Swiss Light Source, cSAXS beamline, Switzerland | 2016-2018 |
| Visiting Researcher | Okinawa Institute of Science and Technology Graduate University, Micro/Bio/Nanofluidics Unit, Japan | 2016 |
| PhD | ETH Zürich, Laboratory of Food Processing, Switzerland | 2013-2016 |
| Master | Materials Science Exploiting Large Scale Facilities (MaMaSelf), University of Rennes, TUM Munich and PSI. | 2010-2012 |
| Bachelor | Universidade Federal do Rio Grande do Sul, Materials Engineering, Brazil | 2005-2009 |
| Project title | Funding source | Collaborators | Amount (CHF) | Period |
| Impact of nanoreactor anisotropy and confinement on chemical reactions | SNSF, Weave project MINT | Prof. Edvaldo Sabadini, UNICAMP, Brazil | 320k | Jan 2025 - Dec 2028 |
| Flow-SAS: deciphering the 3D structure of fluids under flow in situ | PSI Research grant, aiming at strengthening interdisciplinary research of collaborative projects with synergetic added value to PSI. | Prof. Marco Stampanoni, Dr. Christian Schlepütz, and Prof. Markus Strobl | 270k | Sep 2023 – Aug 2027 |
| Microfluidic-small-angle neutron scattering: probing nanostructures in dynamic systems | Research Partnership Grants ASEAN is to establish new scientific collaborations between scientists based in Switzerland and Asia. | Prof. Amy Shen (OIST) | 26k | Feb 2024 – Jan 2025 |
| Shear banding of wormlike micelles | Japan Society for the Promotion of Science. JSPS granted me a joint fellowship with ETH to visit OIST. | Prof. Amy Shen (OIST) and Prof. Peter Fischer (ETH) | 100k | Dec 2015 –Jun 2016 |
Multidisciplinary approach to NPs characterization (MSE-674): Winter semester at EPFL. Course description.
- Scattering of Soft Matter (327-2147-00L): Spring semester at ETH. Course description.
- Darepy: codes developed for data reduction in the git repository.
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Di Spirito NA, Grizzuti N, Lutz-Bueno V, Urciuoli G, Auriemma F, Pasquino R
Pluronic F68 micelles as carriers for an anti-inflammatory drug: a rheological and scattering investigation
Langmuir. 2024; 40(2): 1544-1554. https://doi.org/10.1021/acs.langmuir.3c03682
DORA PSI -
Firth CR, Jeanguenat C, Lutz-Bueno V, Boureau V, Sivula K
A halted photodeposition technique controls co-catalyst loading and morphology on organic semiconductor nanoparticles for solar H2 production
Advanced Energy Materials. 2024. https://doi.org/10.1002/aenm.202403372
DORA PSI -
Fischer P, Lutz-Bueno V
Glycyrrhizic acid aggregates seen from a synthetic surfactant perspective
Physical Chemistry Chemical Physics. 2024; 26(4): 2806-2814. https://doi.org/10.1039/d3cp04835g
DORA PSI -
Hanczyc P, Alfarano SR, Bolisetty S, Zhou J, Peydayesh M, Lutz-Bueno V, et al.
Photonics of hydrothermally treated β-lactoglobulin amyloids
Small Science. 2024; 4(7): 2400054 (10 pp.). https://doi.org/10.1002/smsc.202400054
DORA PSI -
Saade C, Pozza A, Bonneté F, Finet S, Lutz-Bueno V, Tully MD, et al.
Enhanced structure/function of mTSPO translocator in lipid:surfactant mixed micelles
Biochimie. 2024; 224: 3-15. https://doi.org/10.1016/j.biochi.2024.04.008
DORA PSI -
Victorelli FD, Lutz-Bueno V, Santos KP, Wu D, Sturla SJ, Mezzenga R
Cubosomes functionalized with antibodies as a potential strategy for the treatment of HER2-positive breast cancer
Journal of Colloid and Interface Science. 2024; 673: 291-300. https://doi.org/10.1016/j.jcis.2024.06.091
DORA PSI -
Zink JI, Lutz-Bueno V, Handschin S, Dütsch C, Diaz A, Fischer P, et al.
Structural and mechanical anisotropy in plant-based meat analogues
Food Research International. 2024; 179: 113968 (9 pp.). https://doi.org/10.1016/j.foodres.2024.113968
DORA PSI -
Ali A, Ganguillet S, Turgay Y, Keys TG, Causa E, Fradique R, et al.
Surface cross-linking by macromolecular tethers enhances virus-like particles' resilience to mucosal stress factors
ACS Nano. 2023; 18(4): 3382-3396. https://doi.org/10.1021/acsnano.3c10339
DORA PSI -
Björn L, Melhado Mazza R, Andreasson E, Linell F, Lutz-Bueno V, Guizar-Sicairos M, et al.
Scanning small-angle X-ray scattering of injection-molded polymers: anisotropic structure and mechanical properties of low-density polyethylene
ACS Applied Polymer Materials. 2023; 5(8): 6429-6440. https://doi.org/10.1021/acsapm.3c01007
DORA PSI -
De Angelis G, Gray N, Lutz-Bueno V, Amstad E
From surfactants to viscoelastic capsules
Advanced Materials Interfaces. 2023; 10(13): 2202450 (11 pp.). https://doi.org/10.1002/admi.202202450
DORA PSI -
De Angelis G, Lutz-Bueno V, Amstad E
Rheological properties of ionically crosslinked viscoelastic 2D films vs. corresponding 3D bulk hydrogels
ACS Applied Materials and Interfaces. 2023; 15(19): 23758-23764. https://doi.org/10.1021/acsami.3c02675
DORA PSI -
Gonçalves Carvalho Dias AM, Pimentel Moreira I, Lychko I, Lopes Soares C, Nurrito A, Moura Barbosa AJ, et al.
Hierarchical self-assembly of a reflectin-derived peptide
Frontiers in Chemistry. 2023; 11: 1267563 (14 pp.). https://doi.org/10.3389/fchem.2023.1267563
DORA PSI -
Kutzli I, Lutz-Bueno V, Bagnani M, Diaz A, Almohammadi H, Nicholson RA, et al.
From amyloid fibrils to microfiber condensates: tuning microfluidic coextrusion of food-grade β-lactoglobulin-pectin core-shell fibers by changes of protein structure
Food Hydrocolloids. 2023; 143: 108845 (12 pp.). https://doi.org/10.1016/j.foodhyd.2023.108845
DORA PSI -
Li C‐R, Lutz‐Bueno V, Amstad E
Charge‐selectively permeable self‐healing microcapsules
Advanced Materials Interfaces. 2023; 10(35): 2300531 (13 pp.). https://doi.org/10.1002/admi.202300531
DORA PSI -
Peydayesh M, Kistler S, Zhou J, Lutz-Bueno V, Damiani Victorelli F, Bagliotti Meneguin A, et al.
Amyloid-polysaccharide interfacial coacervates as therapeutic materials
Nature Communications. 2023; 14(1): 1848 (11 pp.). https://doi.org/10.1038/s41467-023-37629-z
DORA PSI -
Radiom M, Keys T, Turgay Y, Ali A, Preet S, Chesnov S, et al.
Mechanical tuning of virus-like particles
Journal of Colloid and Interface Science. 2023; 634: 963-971. https://doi.org/10.1016/j.jcis.2022.12.090
DORA PSI -
Victorelli FD, Rodero CF, Lutz-Bueno V, Chorilli M, Mezzenga R
Amyloid fibrils enhance the topical bio-adhesivity of liquid crystalline mesophase-based drug formulations
Advanced Healthcare Materials. 2023; 12(12): 2202720 (9 pp.). https://doi.org/10.1002/adhm.202202720
DORA PSI -
Catalini S, Lutz-Bueno V, Usuelli M, Diener M, Taschin A, Bartolini P, et al.
Multi-length scale structural investigation of lysozyme self-assembly
iScience. 2022; 25(7): 104586 (15 pp.). https://doi.org/10.1016/j.isci.2022.104586
DORA PSI -
Finnilä MAJ, Das Gupta S, Turunen MJ, Hellberg I, Turkiewicz A, Lutz‐Bueno V, et al.
Mineral crystal thickness in calcified cartilage and subchondral bone in healthy and osteoarthritic human knees
Journal of Bone and Mineral Research. 2022; 37(9): 1700-1710. https://doi.org/10.1002/jbmr.4642
DORA PSI -
Gonçalves Carvalho Dias AM, Cena C, Lutz-Bueno V, Mezzenga R, Marques A, Ferreira I, et al.
Solvent modulation in peptide sub-microfibers obtained by solution blow spinning
Frontiers in Chemistry. 2022; 10: 1054347 (9 pp.). https://doi.org/10.3389/fchem.2022.1054347
DORA PSI -
Lutz-Bueno V, Diaz A, Wu T, Nyström G, Geiger T, Antonini C
Hierarchical structure of cellulose nanofibril-based foams explored by multimodal X-ray scattering
Biomacromolecules. 2022; 23(3): 676-686. https://doi.org/10.1021/acs.biomac.1c00521
DORA PSI -
Sun Q, Lutz-Bueno V, Zhou J, Yuan Y, Fischer P
Polymer induced liquid crystal phase behavior of cellulose nanocrystal dispersions
Nanoscale Advances. 2022; 4(22): 4863-4870. https://doi.org/10.1039/d2na00303a
DORA PSI -
Victorelli FD, Salvati Manni L, Biffi S, Bortot B, Buzzá HH, Lutz-Bueno V, et al.
Potential of curcumin-loaded cubosomes for topical treatment of cervical cancer
Journal of Colloid and Interface Science. 2022; 620: 419-430. https://doi.org/10.1016/j.jcis.2022.04.031
DORA PSI -
Liebi M, Lutz-Bueno V, Guizar-Sicairos M, Schönbauer BM, Eichler J, Martinelli E, et al.
3D nanoscale analysis of bone healing around degrading Mg implants evaluated by X-ray scattering tensor tomography
Acta Biomaterialia. 2021; 134: 804-817. https://doi.org/10.1016/j.actbio.2021.07.060
DORA PSI -
Rodriguez-Palomo A, Lutz-Bueno V, Guizar-Sicairos M, Kádár R, Andersson M, Liebi M
Nanostructure and anisotropy of 3D printed lyotropic liquid crystals studied by scattering and birefringence imaging
Additive Manufacturing. 2021; 47: 102289 (9 pp.). https://doi.org/10.1016/j.addma.2021.102289
DORA PSI -
Rodriguez‐Palomo A, Lutz‐Bueno V, Cao X, Kádár R, Andersson M, Liebi M
In situ visualization of the structural evolution and alignment of lyotropic liquid crystals in confined flow
Small. 2021; 17(7): 2006229 (10 pp.). https://doi.org/10.1002/smll.202006229
DORA PSI -
Arboleda C, Lutz-Bueno V, Wang Z, Villanueva-Perez P, Guizar-Sicairos M, Liebi M, et al.
Assessing lesion malignancy by scanning small-angle x-ray scattering of breast tissue with microcalcifications
Physics in Medicine and Biology. 2019; 64(15): 155010 (9 pp.). https://doi.org/10.1088/1361-6560/ab2c36
DORA PSI -
Gao Z, Guizar-Sicairos M, Lutz-Bueno V, Schröter A, Liebi M, Rudin M, et al.
High-speed tensor tomography: iterative reconstruction tensor tomography (IRTT) algorithm
Acta Crystallographica Section A: Foundations and Advances. 2019; 75: 223-238. https://doi.org/10.1107/S2053273318017394
DORA PSI -
Giannini C, Terzi A, Fusaro L, Sibillano T, Diaz A, Ramella M, et al.
Scanning X‐ray microdiffraction of decellularized pericardium tissue at increasing glucose concentration
Journal of Biophotonics. 2019; 12(10): e201900106 (12 pp.). https://doi.org/10.1002/jbio.201900106
DORA PSI -
Giannini C, Ladisa M, Lutz-Bueno V, Terzi A, Ramella M, Fusaro L, et al.
X-ray scanning microscopies of microcalcifications in abdominal aortic and popliteal artery aneurysms
IUCrJ. 2019; 6(2): 267-276. https://doi.org/10.1107/S2052252519001544
DORA PSI -
Leu L, Bertier P, Georgiadis A, Busch A, Diaz A, Klaver J, et al.
SAXS and WAXS microscopy applied to mudrocks: a new method for systematic multiscale studies of porosity, pore orientation and mineralogy
Presented at: Sixth EAGE shale workshop; April 28 - May 1, 2019; Bordeaux, France. https://doi.org/10.3997/2214-4609.201900311
DORA PSI -
Lutz-Bueno V, Arboleda C, Leu L, Blunt MJ, Busch A, Georgiadis A, et al.
Model-free classification of X-ray scattering signals applied to image segmentation
Journal of Applied Crystallography. 2018; 51(5): 1378-1386. https://doi.org/10.1107/S1600576718011032
DORA PSI -
Rajasekharan AK, Lotsari A, Lutz-Bueno V, Liebi M, Andersson M
Bioinspired structural hierarchy within macroscopic volumes of synthetic composites
Advanced Healthcare Materials. 2018; 7(18): 1800466 (7 pp.). https://doi.org/10.1002/adhm.201800466
DORA PSI -
Lutz-Bueno V, Pasquino R, Haward S, Shen AQ, Fischer P
In-situ shear-banding quantification of surfactant solutions in straight microfluidic channels
Journal of Rheology. 2017; 61(4): 769-783. https://doi.org/10.1122/1.4985379
DORA PSI -
Lutz-Bueno V, Liebi M, Kohlbrecher J, Fischer P
Intermicellar interactions and the viscoelasticity of surfactant solutions: complementary use of SANS and SAXS
Langmuir. 2017; 33(10): 2617-2627. https://doi.org/10.1021/acs.langmuir.6b04466
DORA PSI -
Lutz-Bueno V, Isabettini S, Walker F, Kuster S, Liebi M, Fischer P
Ionic micelles and aromatic additives: a closer look at the molecular packing parameter
Physical Chemistry Chemical Physics. 2017; 19(32): 21869-21877. https://doi.org/10.1039/c7cp03891g
DORA PSI -
Lutz-Bueno V, Zhao J, Mezzenga R, Pfohl T, Fischer P, Liebi M
Scanning-SAXS of microfluidic flows: nanostructural mapping of soft matter
Lab on a Chip. 2016; 16(20): 4028-4035. https://doi.org/10.1039/c6lc00690f
DORA PSI -
Lutz-Bueno V, Kohlbrecher J, Fischer P
Shear thickening, temporal shear oscillations, and degradation of dilute equimolar CTAB/NaSal wormlike solutions
Rheologica Acta. 2013; 52(4): 297-312. https://doi.org/10.1007/s00397-012-0672-4
DORA PSI