Protein Engineering
Microbial pathogens cause billions of infections and millions of deaths per year. Detailed knowledge of host-pathogen interactions is therefore fundamental to develop measures to treat infectious diseases caused by microbial pathogens. Using X-ray crystallography and cryo-electron microscopy combined with biochemical and biophysical methods, we study proteins that are relevant for infectious diseases, including botulinum neurotoxin, their receptors and the oxaloactetate decarboxylase complex. Furthermore, we collaborate with industrial and academic partners on microbial pathogen-related research projects that are critically dependent on the availability of high-quality recombinant proteins and their biophysical and structural characterization.
Richard Kammerer, Group leader
Botulinum Neurotoxins and Receptors
Xiaodan Li, Senior Scientist
Structure and function of Membrane proteins related to ion transport
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