Mechanisms of Signal Transduction
Interactions between the cell and its environment, as well as between cellular compartments, occur at the biological membranes. A variety of membrane proteins and protein complexes perform tasks associated with the reception of the extracellular signals and conversion of those signals into biochemical responses inside the cell. We are using protein biochemistry, biophysics and structural biology (X-ray crystallography and cryo-EM) to investigate the structure and function of membrane proteins involved in signal transduction.
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Volodymyr Korkhov, group leader