Publications pre-2020

The list below shows the publications before 2020. You can find the publications from 2020 onwards here.

Publication Pre-2020

del Barrio J, Liu J, Brady RA, Tan CSY, Chiodini S, Ricci M, et al.
Emerging two-dimensional crystallization of cucurbit[8]uril complexes: from supramolecular polymers to nanofibers
Journal of the American Chemical Society. 2019; 141(36): 14021-14025. https://doi.org/10.1021/jacs.9b07506
DORA PSI

Abela E, Missimer JH, Pastore-Wapp M, Krammer W, Wiest R, Weder BJ
Early prediction of long-term tactile object recognition performance after sensorimotor stroke
Cortex. 2019; 115: 264-279. https://doi.org/10.1016/j.cortex.2019.01.018
DORA PSI
Akhmanova A, Steinmetz MO
Microtubule minus-end regulation at a glance
Journal of Cell Science. 2019; 132(11): jcs227850 (7 pp.). https://doi.org/10.1242/jcs.227850
DORA PSI
Atherton J, Luo Y, Xiang S, Yang C, Rai A, Jiang K, et al.
Structural determinants of microtubule minus end preference in CAMSAP CKK domains
Nature Communications. 2019; 10(1): 5236 (16 pp.). https://doi.org/10.1038/s41467-019-13247-6
DORA PSI
Basu S, Olieric V, Leonarski F, Matsugaki N, Kawano Y, Takashi T, et al.
Long-wavelength native-SAD phasing: opportunities and challenges
IUCrJ. 2019; 6(3): 1-14. https://doi.org/10.1107/S2052252519002756
DORA PSI
Bliven SE, Lafita A, Rose PW, Capitani G, Prlić A, Bourne PE
Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm
PLoS Computational Biology. 2019; 15(4): e1006842 (18 pp.). https://doi.org/10.1371/journal.pcbi.1006842
DORA PSI
Blum TB, Hahn A, Meier T, Davies KM, Kühlbrandt W
Dimers of mitochondrial ATP synthase induce membrane curvature and self-assemble into rows
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(10): 4250-4255. https://doi.org/10.1073/pnas.1816556116
DORA PSI
Brindisi M, Ulivieri C, Alfano G, Gemma S, de Asís Balaguer F, Khan T, et al.
Structure-activity relationships, biological evaluation and structural studies of novel pyrrolonaphthoxazepines as antitumor agents
European Journal of Medicinal Chemistry. 2019; 162: 290-320. https://doi.org/10.1016/j.ejmech.2018.11.004
DORA PSI
Brunner JD, Schenck S
Preparation of proteoliposomes with purified TMEM16 protein for accurate measures of lipid scramblase activity
In: Drin G, ed. Intracellular lipid transport. Methods in molecular biology. New York, NY, USA: Humana Press; 2019:181-199. https://doi.org/10.1007/978-1-4939-9136-5_14
DORA PSI
Casadei CM, Nass K, Barty A, Hunter MS, Padeste C, Tsai C-J, et al.
Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals
IUCrJ. 2019; 6: 34-45. https://doi.org/10.1107/S2052252518014641
DORA PSI
Chalupska D, Różycki B, Humpolickova J, Faltova L, Klima M, Boura E
Phosphatidylinositol 4-kinase IIIβ (PI4KB) forms highly flexible heterocomplexes that include ACBD3, 14-3-3, and Rab11 proteins
Scientific Reports. 2019; 9(1): 567 (11 pp.). https://doi.org/10.1038/s41598-018-37158-6
DORA PSI
Chen X, Widmer LA, Stangier MM, Steinmetz MO, Stelling J, Barral Y
Remote control of microtubule plus-end dynamics and function from the minus-end
eLife. 2019; 8: e48627 (32 pp.). https://doi.org/10.7554/eLife.48627
DORA PSI
Cury NM, Mühlethaler T, Laranjeira ABA, Canevarolo RR, Zenatti PP, Lucena-Agell D, et al.
Structural basis of colchicine-site targeting acylhydrazones active against multidrug-resistant acute lymphoblastic leukemia
iScience. 2019; 21: 95-109. https://doi.org/10.1016/j.isci.2019.10.003
DORA PSI
Dohle W, Prota AE, Menchon G, Hamel E, Steinmetz MO, Potter BVL
Tetrahydroisoquinoline sulfamates as potent microtubule disruptors: synthesis, antiproliferative and antitubulin activity of dichlorobenzyl-based derivatives, and a Tubulin cocrystal structure.
ACS Omega. 2019; 4: 755-764. https://doi.org/10.1021/acsomega.8b02879
DORA PSI
Dolenc J, van Gunsteren WF, Prota AE, Steinmetz MO, Missimer JH
Conformational properties of the chemotherapeutic drug analogue Epothilone A: how to model a flexible protein ligand using scarcely available experimental data
Journal of Chemical Information and Modeling. 2019; 59(5): 2218-2230. https://doi.org/10.1021/acs.jcim.9b00171
DORA PSI
Ehrenberg D, Varma N, Deupi X, Koyanagi M, Terakita A, Schertler GFX, et al.
The two-photon reversible reaction of the bistable jumping spider rhodopsin-1
Biophysical Journal. 2019; 116(7): 1248-1258. https://doi.org/10.1016/j.bpj.2019.02.025
DORA PSI
Faltova L, Jiang K, Frey D, Wu Y, Capitani G, Prota AE, et al.
Crystal structure of a heterotetrameric katanin p60:p80 complex
Structure. 2019; 27(9): 1375-1383.e3. https://doi.org/10.1016/j.str.2019.07.002
DORA PSI
Gavriilidou AFM, Hunziker H, Mayer D, Vuckovic Z, Veprintsev DB, Zenobi R
Insights into the basal activity and activation mechanism of the β1 adrenergic receptor using native mass spectrometry
Journal of the American Society for Mass Spectrometry. 2019; 30(3): 529-537. https://doi.org/10.1007/s13361-018-2110-z
DORA PSI
Graeber E, Korkhov VM
Characterisation of the ligand binding sites in the translocator protein TSPO using the chimeric bacterial-mammalian constructs
Protein Expression and Purification. 2019; 164: 105456 (10 pp.). https://doi.org/10.1016/j.pep.2019.105456
DORA PSI
Guo W, Liu B, Yin Y, Kan X, Gong Q, Li Y, et al.
Licochalcone A protects the blood milk barrier integrity and relieves the inflammatory response in LPS-induced mastitis
Frontiers in Immunology. 2019; 10: 287 (14 pp.). https://doi.org/10.3389/fimmu.2019.00287
DORA PSI
Guo W, Liu B, Hu G, Kan X, Li Y, Gong Q, et al.
Vanillin protects the blood-milk barrier and inhibits the inflammatory response in LPS-induced mastitis in mice
Toxicology and Applied Pharmacology. 2019; 365: 9-18. https://doi.org/10.1016/j.taap.2018.12.022
DORA PSI
Górzny MŁ, Opara NL, Guzenko VA, Cadarso VJ, Schift H, Li XD, et al.
Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography
Micro and Nano Engineering. 2019; 3: 31-36. https://doi.org/10.1016/j.mne.2019.03.002
DORA PSI
Haider RS, Wilhelm F, Rizk A, Mutt E, Deupi X, Peterhans C, et al.
Arrestin-1 engineering facilitates complex stabilization with native rhodopsin
Scientific Reports. 2019; 9(1): 439 (13 pp.). https://doi.org/10.1038/s41598-018-36881-4
DORA PSI
Hooikaas PJ, Martin M, Mühlethaler T, Kuijntjes G-J, Peeters CAE, Katrukha EA, et al.
MAP7 family proteins regulate kinesin-1 recruitment and activation
Journal of Cell Biology. 2019; 218(4): 1298-1318. https://doi.org/10.1083/jcb.201808065
DORA PSI
Jaeger K, Bruenle S, Weinert T, Guba W, Muehle J, Miyazaki T, et al.
Structural basis for allosteric ligand recognition in the human CC chemokine receptor 7
Cell. 2019; 178(5): 1222-1230. https://doi.org/10.1016/j.cell.2019.07.028
DORA PSI
James D, Weinert T, Skopintsev P, Furrer A, Gashi D, Tanaka T, et al.
Improving high viscosity extrusion of microcrystals for time-resolved serial femtosecond crystallography at X-ray lasers
Journal of Visualized Experiments. 2019; 2019(144): e59087 (12 pp.). https://doi.org/10.3791/59087
DORA PSI
Kan X, Liu B, Guo W, Wei L, Lin Y, Guo Y, et al.
Myricetin relieves LPS-induced mastitis by inhibiting inflammatory response and repairing the blood-milk barrier
Journal of Cellular Physiology. 2019; 234(9): 16252-16262. https://doi.org/10.1002/jcp.28288
DORA PSI
Kashyap AS, Fernandez-Rodriguez L, Zhao Y, Monaco G, Trefny MP, Yoshida N, et al.
GEF-H1 signaling upon microtubule destabilization is required for dendritic cell activation and specific anti-tumor responses
Cell Reports. 2019; 28(13): 3367-3380.e1. https://doi.org/10.1016/j.celrep.2019.08.057
DORA PSI
La Sala G, Olieric N, Sharma A, Viti F, de Asis Balaguer Perez F, Huang L, et al.
Structure, thermodynamics, and kinetics of plinabulin binding to two tubulin isotypes
Chem. 2019; 5(11): 2969-2986. https://doi.org/10.1016/j.chempr.2019.08.022
DORA PSI
Liu B, Huang B, Hu G, He D, Li Y, Ran X, et al.
Isovitexin-mediated regulation of microglial polarization in lipopolysaccharide-induced neuroinflammation via activation of the CaMKKβ/AMPK-PGC-1α signaling axis
Frontiers in Immunology. 2019; 10: 2650 (17 pp.). https://doi.org/10.3389/fimmu.2019.02650
DORA PSI
Mayer D, Damberger FF, Samarasimhareddy M, Feldmueller M, Vuckovic Z, Flock T, et al.
Distinct G protein-coupled receptor phosphorylation motifs modulate arrestin affinity and activation and global conformation
Nature Communications. 2019; 10: 1261 (14 pp.). https://doi.org/10.1038/s41467-019-09204-y
DORA PSI
Montaldo NP, Bordin DL, Brambilla A, Rösinger M, Fordyce Martin SL, Bjørås KØ, et al.
Alkyladenine DNA glycosylase associates with transcription elongation to coordinate DNA repair with gene expression
Nature Communications. 2019; 10(1): 5460 (13 pp.). https://doi.org/10.1038/s41467-019-13394-w
DORA PSI
Munk C, Mutt E, Isberg V, Nikolajsen LF, Bibbe JM, Flock T, et al.
An online resource for GPCR structure determination and analysis
Nature Methods. 2019; 16(2): 151-162. https://doi.org/10.1038/s41592-018-0302-x
DORA PSI
Nagata T, Koyanagi M, Tsukamoto H, Mutt E, Schertler GFX, Deupi X, et al.
The counterion–retinylidene Schiff base interaction of an invertebrate rhodopsin rearranges upon light activation
Communications Biology. 2019; 2: 180 (9 pp.). https://doi.org/10.1038/s42003-019-0409-3
DORA PSI
Patterson JC, Joughin BA, Prota AE, Mühlethaler T, Jonas OH, Whitman MA, et al.
VISAGE reveals a targetable mitotic spindle vulnerability in cancer cells
Cell Systems. 2019; 9(1): 74-92.e8. https://doi.org/10.1016/j.cels.2019.05.009
DORA PSI
Qi C, Minin GD, Vercellino I, Wutz A, Korkhov VM
Structural basis of sterol recognition by human hedgehog receptor PTCH1
Science Advances. 2019; 5(9): eaaw6490 (9 pp.). https://doi.org/10.1126/sciadv.aaw6490
DORA PSI
Qi C, Sorrentino S, Medalia O, Korkhov VM
The structure of a membrane adenylyl cyclase bound to an activated stimulatory G protein
Science. 2019; 364(6438): 389-394. https://doi.org/10.1126/science.aav0778
DORA PSI
Samarasimhareddy M, Mayer D, Metanis N, Veprintsev D, Hurevich M, Friedler A
A targeted approach for the synthesis of multi-phosphorylated peptides: a tool for studying the role of phosphorylation patterns in proteins
Organic and Biomolecular Chemistry. 2019; 17(42): 9284-9290. https://doi.org/10.1039/c9ob01874c
DORA PSI
Standfuss J
Membrane protein dynamics studied by X-ray lasers - or why only time will tell
Current Opinion in Structural Biology. 2019; 57: 63-71. https://doi.org/10.1016/j.sbi.2019.02.001
DORA PSI
Tsai C-J, Marino J, Adaixo R, Pamula F, Muehle J, Maeda S, et al.
Cryo-EM structure of the rhodopsin-Gαi-βγ complex reveals binding of the rhodopsin C-terminal tail to the gβ subunit
eLife. 2019; 8: e46041 (19 pp.). https://doi.org/10.7554/eLife.46041
DORA PSI
Varma N, Mutt E, Mühle J, Panneels V, Terakita A, Deupi X, et al.
Crystal structure of jumping spider rhodopsin-1 as a light sensitive GPCR
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2019; 116(29): 14547-14556. https://doi.org/10.1073/pnas.1902192116
DORA PSI
Wang N, Bosc C, Ryul Choi S, Boulan B, Peris L, Olieric N, et al.
Structural basis of tubulin detyrosination by the vasohibin–SVBP enzyme complex
Nature Structural and Molecular Biology. 2019; 26(7): 571-582. https://doi.org/10.1038/s41594-019-0241-y
DORA PSI
Weinert T, Skopintsev P, James D, Dworkowski F, Panepucci E, Kekilli D, et al.
Proton uptake mechanism in bacteriorhodopsin captured by serial synchrotron crystallography
Science. 2019; 365(6448): 61-65. https://doi.org/10.1126/science.aaw8634
DORA PSI
Wickstrand C, Nogly P, Nango E, Iwata S, Standfuss J, Neutze R
Bacteriorhodopsin: structural insights revealed using X-ray lasers and synchrotron radiation
Annual Review of Biochemistry. 2019; 88: 59-83. https://doi.org/10.1146/annurev-biochem-013118-111327
DORA PSI
Xie Y, Mansouri M, Rizk A, Berger P
Regulation of VEGFR2 trafficking and signaling by Rab GTPase-activating proteins
Scientific Reports. 2019; 9(1): 13342 (12 pp.). https://doi.org/10.1038/s41598-019-49646-4
DORA PSI
Zhu X, Poghosyan E, Rezabkova L, Mehall B, Sakakibara H, Hirono M, et al.
The roles of a flagellar HSP40 ensuring rhythmic beating
Molecular Biology of the Cell. 2019; 30(2): 228-241. https://doi.org/10.1091/mbc.E18-01-0047
DORA PSI
de Asís Balaguer F, Mühlethaler T, Estévez-Gallego J, Calvo E, Giménez-Abián JF, Risinger AL, et al.
Crystal structure of the cyclostreptin-tubulin adduct: implications for tubulin activation by taxane-site ligands
International Journal of Molecular Sciences. 2019; 20(6): 1392 (17 pp.). https://doi.org/10.3390/ijms20061392
DORA PSI
Żyła DS, Prota AE, Capitani G, Glockshuber R
Alternative folding to a monomer or homopolymer is a common feature of the type 1 pilus subunit FimA from enteroinvasive bacteria
Journal of Biological Chemistry. 2019; 294(27): 10553-10563. https://doi.org/10.1074/jbc.RA119.008610
DORA PSI

Aher A, Kok M, Sharma A, Rai A, Olieric N, Rodriguez-Garcia R, et al.
CLASP suppresses microtubule catastrophes through a single TOG domain
Developmental Cell. 2018; 46(1): 40-58.e8. https://doi.org/10.1016/j.devcel.2018.05.032
DORA PSI
Ballmer-Hofer K, Hyde CAC, Schleier T, Avramovic D
ScFvs as allosteric inhibitors of VEGFR-2: novel tools to harness VEGF signaling
International Journal of Molecular Sciences. 2018; 19(5): 1334 (15 pp.). https://doi.org/10.3390/ijms19051334
DORA PSI
Ballmer-Hofer K
Vascular Endothelial Growth Factor, from basic research to clinical applications
International Journal of Molecular Sciences. 2018; 19(12): 3750 (5 pp.). https://doi.org/10.3390/ijms19123750
DORA PSI
Beazley-Long N, Moss CE, Ashby WR, Bestall SM, Almahasneh F, Durrant AM, et al.
VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis
Brain, Behavior, and Immunity. 2018; 74: 49-67. https://doi.org/10.1016/j.bbi.2018.03.012
DORA PSI
Bianchi S, Rogala KB, Dynes NJ, Hilbert M, Leidel SA, Steinmetz MO, et al.
Interaction between the Caenorhabditis elegans centriolar protein SAS-5 and microtubules facilitates organelle assembly
Molecular Biology of the Cell. 2018; 29(6): 722-735. https://doi.org/10.1091/mbc.E17-06-0412
DORA PSI
Bliven S, Lafita A, Parker A, Capitani G, Duarte JM
Automated evaluation of quaternary structures from protein crystals
PLoS Computational Biology. 2018; 14(4): e1006104 (19 pp.). https://doi.org/10.1371/journal.pcbi.1006104
DORA PSI
Bueno O, Estévez Gallego J, Martins S, Prota AE, Gago F, Gómez-SanJuan A, et al.
High-affinity ligands of the colchicine domain in tubulin based on a structure-guided design
Scientific Reports. 2018; 8(1): 4242 (17 pp.). https://doi.org/10.1038/s41598-018-22382-x
DORA PSI
Casadei CM, Tsai C-J, Barty A, Hunter MS, Zatsepin NA, Padeste C, et al.
Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals
IUCrJ. 2018; 5(1): 103-117. https://doi.org/10.1107/S2052252517017043
DORA PSI
Dohle W, Jourdan FL, Menchon G, Prota AE, Foster PA, Mannion P, et al.
Quinazolinone-based anticancer agents: synthesis, antiproliferative SAR, antitubulin activity, and tubulin Co-crystal structure
Journal of Medicinal Chemistry. 2018; 61(3): 1031-1044. https://doi.org/10.1021/acs.jmedchem.7b01474
DORA PSI
Field JJ, Pera B, Estévez Gallego J, Calvo E, Rodríguez-Salarichs J, Sáez-Calvo G, et al.
Zampanolide binding to tubulin indicates cross-talk of taxane site with colchicine and nucleotide sites
Journal of Natural Products. 2018; 81(3): 494-505. https://doi.org/10.1021/acs.jnatprod.7b00704
DORA PSI
Gavriilidou AFM, Holding FP, Mayer D, Coyle JE, Veprintsev DB, Zenobi R
Native mass spectrometry gives insight into the allosteric binding mechanism of M2 pyruvate kinase to fructose-1,6-bisphosphate
Biochemistry. 2018; 57(11): 1685-1689. https://doi.org/10.1021/acs.biochem.7b01270
DORA PSI
Gerrard E, Mutt E, Nagata T, Koyanagi M, Flock T, Lesca E, et al.
Convergent evolution of tertiary structure in rhodopsin visual proteins from vertebrates and box jellyfish
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2018; 115(24): 6201-6206. https://doi.org/10.1073/pnas.1721333115
DORA PSI
Gorobtsov OY, Mercurio G, Capotondi F, Skopintsev P, Lazarev S, Zaluzhnyy IA, et al.
Seeded X-ray free-electron laser generating radiation with laser statistical properties
Nature Communications. 2018; 9(1): 4498 (6 pp.). https://doi.org/10.1038/s41467-018-06743-8
DORA PSI
Graeber E, Korkhov VM
Expression and purification of the mammalian translocator protein for structural studies
PLoS One. 2018; 13(6): e0198832 (17 pp.). https://doi.org/10.1371/journal.pone.0198832
DORA PSI
Gruene T, Li T, van Genderen E, Pinar AB, van Bokhoven JA
Characterization at the level of individual crystals: single-crystal MFI type zeolite grains
Chemistry: A European Journal. 2018; 24(10): 2384-2388. https://doi.org/10.1002/chem.201704213
DORA PSI
Gruene T, Wennmacher JTC, Zaubitzer C, Holstein JJ, Heidler J, Fecteau-Lefebvre A, et al.
Rapid structure determination of microcrystalline molecular compounds using electron diffraction
Angewandte Chemie International Edition. 2018; 57(50): 16313-16317. https://doi.org/10.1002/anie.201811318
DORA PSI
Hajizadeh NR, Pieprzyk J, Skopintsev P, Flayhan A, Svergun DI, Löw C
Probing the architecture of a multi-PDZ domain protein: structure of PDZK1 in solution
Structure. 2018; 26(11): 1522-1533. https://doi.org/10.1016/j.str.2018.07.016
DORA PSI
Holler M, Raabe J, Diaz A, Guizar-Sicairos M, Wepf R, Odstrcil M, et al.
OMNY – a tOMography Nano crYo stage
Review of Scientific Instruments. 2018; 89(4): 043706 (13 pp.). https://doi.org/10.1063/1.5020247
DORA PSI
Huang C-Y, Olieric V, Howe N, Warshamanage R, Weinert T, Panepucci E, et al.
In situ serial crystallography for rapid de novo membrane protein structure determination.
Communications Biology. 2018; 1: 124 (8 pp.). https://doi.org/10.1038/S42003-018-0123-6
DORA PSI
Ishikawa T
Organization of dyneins in the axoneme
In: King SM, ed. Dyneins: The biology of dynein motors. Amsterdam: Elsevier; 2018:203-217. https://doi.org/10.1016/B978-0-12-809471-6.00006-1
DORA PSI
Jiang K, Faltova L, Hua S, Capitani G, Prota AE, Landgraf C, et al.
Structural basis of formation of the microtubule minus-end-regulating CAMSAP-katanin complex
Structure. 2018; 26(3): 375-382. https://doi.org/10.1016/j.str.2017.12.017
DORA PSI
Kraatz SHW, Bianchi S, Steinmetz MO
Combinatorial use of disulfide bridges and native sulfur-SAD phasing for rapid structure determination of coiled-coils
Bioscience Reports. 2018; 38(5): BSR20181073 (11 pp.). https://doi.org/10.1042/BSR20181073
DORA PSI
Lafita A, Bliven S, Kryshtafovych A, Bertoni M, Monastyrskyy B, Duarte JM, et al.
Assessment of protein assembly prediction in CASP12
Proteins. 2018; 86(S1): 247-256. https://doi.org/10.1002/prot.25408
DORA PSI
Lampert F, Stafa D, Goga A, Soste MV, Gilberto S, Olieric N, et al.
The multi-subunit GID/CTLH e3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation
eLife. 2018; 7: e35528 (23 pp.). https://doi.org/10.7554/eLife.35528
DORA PSI
Lesca E, Panneels V, Schertler GFX
The role of water molecules in phototransduction of retinal proteins and G protein-coupled receptors
Faraday Discussions. 2018; 207: 27-37. https://doi.org/10.1039/c7fd00207f
DORA PSI
Liu T, Ish-Shalom S, Torng W, Lafita A, Bock C, Mort M, et al.
Biological and functional relevance of CASP predictions
Proteins. 2018; 86(1): 374-386. https://doi.org/10.1002/prot.25396
DORA PSI
Mansouri M, Berger P
Baculovirus for gene delivery to mammalian cells: past, present and future
Plasmid. 2018; 98: 1-7. https://doi.org/10.1016/j.plasmid.2018.05.002
DORA PSI
Mansouri M, Berger P
Multigene delivery in mammalian cells: recent advances and applications
Biotechnology Advances. 2018; 36(4): 871-879. https://doi.org/10.1016/j.biotechadv.2018.01.012
DORA PSI
Mattle D, Kuhn B, Aebi J, Bedoucha M, Kekilli D, Grozinger N, et al.
Ligand channel in pharmacologically stabilized rhodopsin
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2018; 115(14): 3640-3645. https://doi.org/10.1073/pnas.1718084115
DORA PSI
Menchon G, Prota AE, Lucena-Agell D, Bucher P, Jansen R, Irschik H, et al.
A fluorescence anisotropy assay to discover and characterize ligands targeting the maytansine site of tubulin
Nature Communications. 2018; 9(1): 2106 (9 pp.). https://doi.org/10.1038/s41467-018-04535-8
DORA PSI
Menchon G, Maveyraud L, Czaplicki G
Molecular dynamics as a tool for virtual ligand screening
In: Gore M, Jagtap UB, eds. Computational drug discovery and design. Methods in molecular biology. New York: Humana Press; 2018:145-178. https://doi.org/10.1007/978-1-4939-7756-7_9
DORA PSI
Narwal M, Jemth AS, Gustafsson R, Almlöf I, Warpman Berglund U, Helleday T, et al.
Crystal structures and inhibitor interactions of mouse and dog MTH1 reveal species-specific differences in affinity
Biochemistry. 2018; 57(5): 593-603. https://doi.org/10.1021/acs.biochem.7b01163
DORA PSI
Nogly P, Weinert T, James D, Carbajo S, Ozerov D, Furrer A, et al.
Retinal isomerization in bacteriorhodopsin captured by a femtosecond x-ray laser
Science. 2018; 361(6398): eaat0094 (7 pp.). https://doi.org/10.1126/science.aat0094
DORA PSI
Preobraschenski J, Cheret C, Ganzella M, Zander JF, Richter K, Schenck S, et al.
Dual and direction-selective mechanisms of phosphate transport by the vesicular glutamate transporter
Cell Reports. 2018; 23(2): 535-545. https://doi.org/10.1016/j.celrep.2018.03.055
DORA PSI
Rose M, Senkbeil T, von Gundlach AR, Stuhr S, Rumancev C, Dzhigaev D, et al.
Quantitative ptychographic bio-imaging in the water window
Optics Express. 2018; 26(2): 1237-1254. https://doi.org/10.1364/OE.26.001237
DORA PSI
Sharma A, Gerard SF, Olieric N, Steinmetz MO
Cep120 promotes microtubule formation through a unique tubulin binding C2 domain
Journal of Structural Biology. 2018; 203(1): 62-70. https://doi.org/10.1016/j.jsb.2018.01.009
DORA PSI
Smedley CJ, Stanley PA, Qazzaz ME, Prota AE, Olieric N, Collins H, et al.
Sustainable syntheses of (-)-jerantinines A & E and structural characterisation of the jerantinine-tubulin complex at the colchicine binding site
Scientific Reports. 2018; 8(1): 10617 (7 pp.). https://doi.org/10.1038/s41598-018-28880-2
DORA PSI
Stangier MM, Kumar A, Chen X, Farcas A-M, Barral Y, Steinmetz MO
Structure-function relationship of the Bik1-Bim1 complex
Structure. 2018; 26(4): 607-618.e4. https://doi.org/10.1016/j.str.2018.03.003
DORA PSI
Steinmetz MO, Prota AE
Microtubule-targeting agents: strategies to hijack the cytoskeleton
Trends in Cell Biology. 2018; 28(10): 776-792. https://doi.org/10.1016/j.tcb.2018.05.001
DORA PSI
Thieltges KM, Avramovic D, Piscitelli CL, Markovic-Mueller S, Binz HK, Ballmer-Hofer K
Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling
Angiogenesis. 2018; 21(3): 533-543. https://doi.org/10.1007/s10456-018-9606-9
DORA PSI
Tinti G, Fröjdh E, van Genderen E, Gruene T, Schmitt B, de Winter DAM, et al.
Electron crystallography with the EIGER detector
IUCrJ. 2018; 5(2): 190-199. https://doi.org/10.1107/S2052252518000945
DORA PSI
Toledo RA, Garralda E, Mitsi M, Pons T, Monsech J, Vega E, et al.
Exome sequencing of plasma DNA portrays the mutation landscape of colorectal cancer and discovers mutated VEGFR2 receptors as modulators of antiangiogenic therapies
Clinical Cancer Research. 2018; 24(15): 3550-3559. https://doi.org/10.1158/1078-0432.CCR-18-0103
DORA PSI
Tsai C-J, Pamula F, Nehmé R, Mühle J, Weinert T, Flock T, et al.
Crystal structure of rhodopsin in complex with a mini-G_o sheds light on the principles of G protein selectivity
Science Advances. 2018; 4(9): aat7052 (9 pp.). https://doi.org/10.1126/sciadv.aat7052
DORA PSI
Ved N, Da Vitoria Lobo ME, Bestall SM, Vidueira CL, Beazley-Long N, Ballmer-Hofer K, et al.
Diabetes-induced microvascular complications at the level of the spinal cord: a contributing factor in diabetic neuropathic pain
Journal of Physiology. 2018; 596(16): 3675-3693. https://doi.org/10.1113/JP275067
DORA PSI
Weisstanner C, Kägi G, Krammer W, Eap CB, Wiest R, Missimer JH, et al.
The effect of a single dose of escitalopram on sensorimotor networks
Brain and Behavior. 2018; 8(6): e00975 (16 pp.). https://doi.org/10.1002/brb3.975
DORA PSI
Wu Y, Honegger A, Batyuk A, Mittl PRE, Plückthun A
Structural basis for the selective inhibition of c-Jun N-terminal kinase 1 determined by rigid DARPin-DARPin fusions
Journal of Molecular Biology. 2018; 430(14): 2128-2138. https://doi.org/10.1016/j.jmb.2017.10.032
DORA PSI
Ziemski M, Jomaa A, Mayer D, Rutz S, Giese C, Veprintsev D, et al.
Cdc48-like protein of actinobacteria (Cpa) is a novel proteasome interactor in mycobacteria and related organisms
eLife. 2018; 7: e34055 (27 pp.). https://doi.org/10.7554/eLife.34055
DORA PSI

Abela R, Beaud P, van Bokhoven JA, Chergui M, Feurer T, Haase J, et al.
Perspective: opportunities for ultrafast science at SwissFEL
Structural Dynamics. 2017; 4(6): 61602 (25 pp.). https://doi.org/10.1063/1.4997222
DORA PSI
Aeschimann W, Staats S, Kammer S, Olieric N, Jeckelmann J-M, Fotiadis D, et al.
Self-assembled α-tocopherol transfer protein nanoparticles promote vitamin E delivery across an endothelial barrier
Scientific Reports. 2017; 7: 4970 (13 pp.). https://doi.org/10.1038/s41598-017-05148-9
DORA PSI
Atherton J, Jiang K, Stangier MM, Luo Y, Hua S, Houben K, et al.
A structural model for microtubule minus-end recognition and protection by CAMSAP proteins
Nature Structural and Molecular Biology. 2017; 24(11): 931-943. https://doi.org/10.1038/nsmb.3483
DORA PSI
Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, et al.
A new inhibitor of the β-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling
Nature Communications. 2017; 8: 15054 (16 pp.). https://doi.org/10.1038/ncomms15054
DORA PSI
Benoit RM, Schärer MA, Wieser MM, Li X, Frey D, Kammerer RA
Crystal structure of the BoNT/A2 receptor-binding domain in complex with the luminal domain of its neuronal receptor SV2C
Scientific Reports. 2017; 7: 43588 (7 pp.). https://doi.org/10.1038/srep43588
DORA PSI
Bohnacker T, Prota AE, Beaufils F, Burke JE, Melone A, Inglis AJ, et al.
Deconvolution of buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention
Nature Communications. 2017; 8: 14683 (13 pp.). https://doi.org/10.1038/ncomms14683
DORA PSI
Burnett A, Gomez I, Davila De Leon D, Ariaans M, Progias P, Kammerer RA, et al.
Angiopoietin-1 enhances neutrophil chemotaxis in vitro and migration in vivo through interaction with CD18 and release of CCL4
Scientific Reports. 2017; 7(1): 2332 (9 pp.). https://doi.org/10.1038/s41598-017-02216-y
DORA PSI
Buscema M, Matviykiv S, Mészáros T, Gerganova G, Weinberger A, Mettal U, et al.
Immunological response to nitroglycerin-loaded shear-responsive liposomes in vitro and in vivo
Journal of Controlled Release. 2017; 264: 14-23. https://doi.org/10.1016/j.jconrel.2017.08.010
DORA PSI
Canela M-D, Noppen S, Bueno O, Prota AE, Bargsten K, Sáez-Calvo G, et al.
Antivascular and antitumor properties of the tubulin-binding chalcone TUB091
Oncotarget. 2017; 8(9): 14325-14342. https://doi.org/10.18632/oncotarget.9527
DORA PSI
Chalupska D, Eisenreichova A, Różycki B, Rezabkova L, Humpolickova J, Klima M, et al.
Structural analysis of phosphatidylinositol 4-kinase IIIβ (PI4KB) - 14-3-3 protein complex reveals internal flexibility and explains 14-3-3 mediated protection from degradation in vitro
Journal of Structural Biology. 2017; 200(1): 36-44. https://doi.org/10.1016/j.jsb.2017.08.006
DORA PSI
Clabbers MTB, van Genderen E, Wan W, Wiegers EL, Gruene T, Abrahams JP
Protein structure determination by electron diffraction using a single three-dimensional nanocrystal
Acta Crystallographica Section D: Structural Biology. 2017; 73(9): 738-748. https://doi.org/10.1107/S2059798317010348
DORA PSI
Gaspari R, Prota AE, Bargsten K, Cavalli A, Steinmetz MO
Structural basis of cis- and trans-combretastatin binding to tubulin
Chem. 2017; 2(1): 102-113. https://doi.org/10.1016/j.chempr.2016.12.005
DORA PSI
Gorobtsov OY, Mercurio G, Brenner G, Lorenz U, Gerasimova N, Kurta RP, et al.
Statistical properties of a free-electron laser revealed by Hanbury Brown-Twiss interferometry
Physical Review A. 2017; 95(2): 023843 (16 pp.). https://doi.org/10.1103/PhysRevA.95.023843
DORA PSI
Haider RS, Rizk A, Schertler GFX, Ostermaier MK
Comprehensive analysis of the role of arrestin residues in receptor binding
In: Gurevich VV, ed. The structural basis of arrestin functions. Cham: Springer; 2017:83-102. https://doi.org/10.1007/978-3-319-57553-7_7
DORA PSI
Hamel V, Steib E, Hamelin R, Armand F, Borgers S, Flückiger I, et al.
Identification of Chlamydomonas central core centriolar proteins reveals a role for human WDR90 in ciliogenesis
Current Biology. 2017; 27(16): 2486-2498. https://doi.org/10.1016/j.cub.2017.07.011
DORA PSI
Henning S, Ishikawa H, Kühn L, Herranz J, Müller E, Eychmüller A, et al.
Unsupported Pt-Ni aerogels with enhanced high current performance and durability in fuel cell cathodes
Angewandte Chemie International Edition. 2017; 56(36): 10707-10710. https://doi.org/10.1002/anie.201704253
DORA PSI
Heydenreich FM, Miljuš T, Jaussi R, Benoit R, Milić D, Veprintsev DB
High-throughput mutagenesis using a two-fragment PCR approach
Scientific Reports. 2017; 7: 6787 (11 pp.). https://doi.org/10.1038/s41598-017-07010-4
DORA PSI
Holler M, Guizar-Sicairos M, Tsai EHR, Dinapoli R, Müller E, Bunk O, et al.
High-resolution non-destructive three-dimensional imaging of integrated circuits
Nature. 2017; 543(7645): 402-406. https://doi.org/10.1038/nature21698
DORA PSI
Holler M, Raabe J, Wepf R, Shahmoradian SH, Diaz A, Sarafimov B, et al.
OMNY PIN - a versatile sample holder for tomographic measurements at room and cryogenic temperatures
Review of Scientific Instruments. 2017; 88(11): 113701 (9 pp.). https://doi.org/10.1063/1.4996092
DORA PSI
Isabettini S, Liebi M, Kohlbrecher J, Ishikawa T, Fischer P, Windhab EJ, et al.
Mastering the magnetic susceptibility of magnetically responsive bicelles with 3β-amino-5-cholestene and complexed lanthanide ions
Physical Chemistry Chemical Physics. 2017; 19(17): 10820-10824. https://doi.org/10.1039/c7cp01025g
DORA PSI
Isabettini S, Baumgartner ME, Reckey PQ, Kohlbrecher J, Ishikawa T, Fischer P, et al.
Methods for generating highly magnetically responsive lanthanide-chelating phospholipid polymolecular assemblies
Langmuir. 2017; 33(25): 6363-6371. https://doi.org/10.1021/acs.langmuir.7b00725
DORA PSI
Isabettini S, Massabni S, Hodzic A, Durovic D, Kohlbrecher J, Ishikawa T, et al.
Molecular engineering of lanthanide ion chelating phospholipids generating assemblies with a switched magnetic susceptibility
Physical Chemistry Chemical Physics. 2017; 19(31): 20991-21002. https://doi.org/10.1039/c7cp03994h
DORA PSI
Ishikawa T
Axoneme structure from motile cilia
Cold Spring Harbor Perspectives in Biology. 2017; 9(1): a028076 (18 pp.). https://doi.org/10.1101/cshperspect.a028076
DORA PSI
Jiang S, Wang L, Huang M, Jia Z, Weinert T, Warkentin E, et al.
DM9 domain containing protein functions as a pattern recognition receptor with broad microbial recognition spectrum
Frontiers in Immunology. 2017; 8: 1607 (17 pp.). https://doi.org/10.3389/fimmu.2017.01607
DORA PSI
Jiang K, Rezabkova L, Hua S, Liu Q, Capitani G, Altelaar AFM, et al.
Microtubule minus-end regulation at spindle poles by an ASPM-katanin complex
Nature Cell Biology. 2017; 19(5): 480-492. https://doi.org/10.1038/ncb3511
DORA PSI
Jost M, Chen Y, Gilbert LA, Horlbeck MA, Krenning L, Menchon G, et al.
Combined CRISPRi/a-based chemical genetic screens reveal that rigosertib is a microtubule-destabilizing agent
Molecular Cell. 2017; 68(1): 210-223. https://doi.org/10.1016/j.molcel.2017.09.012
DORA PSI
Jost C, Stüber JC, Honegger A, Wu Y, Batyuk A, Plückthun A
Rigidity of the extracellular part of HER2: evidence from engineering subdomain interfaces and shared-helix DARPin-DARPin fusions
Protein Science. 2017; 26(9): 1796-1806. https://doi.org/10.1002/pro.3216
DORA PSI
Kaplan AR, Brady MR, Maciejewski MW, Kammerer RA, Alexandrescu AT
Nuclear magnetic resonance structures of GCN4p are largely conserved when ion pairs are disrupted at acidic pH but show a relaxation of the coiled coil superhelix
Biochemistry. 2017; 56(11): 1604-1619. https://doi.org/10.1021/acs.biochem.6b00634
DORA PSI
Klima M, Chalupska D, Różycki B, Humpolickova J, Rezabkova L, Silhan J, et al.
Kobuviral non-structural 3A proteins act as molecular harnesses to hijack the host ACBD3 protein
Structure. 2017; 25(2): 219-230. https://doi.org/10.1016/j.str.2016.11.021
DORA PSI
Kumar A, Manatschal C, Rai A, Grigoriev I, Steiner Degen M, Jaussi R, et al.
Short linear sequence motif LxxPTPh targets diverse proteins to growing microtubule ends
Structure. 2017; 25(6): 924-932. https://doi.org/10.1016/j.str.2017.04.010
DORA PSI
Lovric S, Goncalves S, Gee HY, Oskouian B, Srinivas H, Choi W-I, et al.
Mutations in sphingosine-1-phosphate lyase cause nephrosis with ichthyosis and adrenal insufficiency
Journal of Clinical Investigation. 2017; 127(3): 912-928. https://doi.org/10.1172/JCI89626
DORA PSI
Mansouri M, Ehsaei Z, Taylor V, Berger P
Baculovirus-based genome editing in primary cells
Plasmid. 2017; 90: 5-9. https://doi.org/10.1016/j.plasmid.2017.01.003
DORA PSI
Markovic-Mueller S, Stuttfeld E, Asthana M, Weinert T, Bliven S, Goldie KN, et al.
Structure of the full-length VEGFR-1 extracellular domain in complex with VEGF-A
Structure. 2017; 25(2): 341-352. https://doi.org/10.1016/j.str.2016.12.012
DORA PSI
Martin-Garcia JM, Conrad CE, Nelson G, Stander N, Zatsepin NA, Zook J, et al.
Serial millisecond crystallography of membrane and soluble protein microcrystals using synchrotron radiation
IUCrJ. 2017; 4: 439-454. https://doi.org/10.1107/S205225251700570X
DORA PSI
Neuhaus F, Mueller D, Tanasescu R, Balog S, Ishikawa T, Brezesinski G, et al.
Vesicle origami: cuboid phospholipid vesicles formed by template-free self-assembly
Angewandte Chemie International Edition. 2017; 56(23): 6515-6518. https://doi.org/10.1002/anie.201701634
DORA PSI
Obbineni JM, Yamamoto R, Ishikawa T
A simple and fast approach for missing-wedge invariant classification of subtomograms extracted from filamentous structures
Journal of Structural Biology. 2017; 197(2): 145-154. https://doi.org/10.1016/j.jsb.2016.08.003
DORA PSI
Oberthuer D, Knoška J, Wiedorn MO, Beyerlein KR, Bushnell DA, Kovaleva EG, et al.
Double-flow focused liquid injector for efficient serial femtosecond crystallography
Scientific Reports. 2017; 7: 44628 (10 pp.). https://doi.org/10.1038/srep44628
DORA PSI
Oezelt H, Kirk E, Wohlhüter P, Müller E, Heyderman LJ, Kovacs A, et al.
Vortex motion in amorphous ferrimagnetic thin film elements
AIP Advances. 2017; 7(5): 056001 (5 pp.). https://doi.org/10.1063/1.4973295
DORA PSI
Paulino C, Neldner Y, Lam AKM, Kalienkova V, Brunner JD, Schenck S, et al.
Structural basis for anion conduction in the calcium-activated chloride channel TMEM16A
eLife. 2017; 6: e26232 (23 pp.). https://doi.org/10.7554/eLife.26232
DORA PSI
Prota AE, Bargsten K, Redondo-Horcajo M, Smith AB, Yang C-PH, McDaid HM, et al.
Structural basis of microtubule stabilization by discodermolide
ChemBioChem. 2017; 18(10): 905-909. https://doi.org/10.1002/cbic.201600696
DORA PSI
Radli M, Veprintsev DB, Rüdiger SGD
Production and purification of human Hsp90β in Escherichia coli
PLoS One. 2017; 12(6): e0180047 (20 pp.). https://doi.org/10.1371/journal.pone.0180047
DORA PSI
Rezabkova L, Jiang K, Capitani G, Prota AE, Akhmanova A, Steinmetz MO, et al.
Structural basis of katanin p60:p80 complex formation
Scientific Reports. 2017; 7: 14893 (8 pp.). https://doi.org/10.1038/s41598-017-14194-2
DORA PSI
Rheinberger J, Hassaine G, Chami M, Stahlberg H, Vogel H, Li X
Two-dimensional crystallization of the mouse serotonin 5-HT_3A receptor
Micron. 2017; 92: 19-24. https://doi.org/10.1016/j.micron.2016.10.004
DORA PSI
Schenck S, Kunz L, Sahlender D, Pardon E, Geertsma ER, Savtchouk I, et al.
Generation and characterization of anti-VGLUT nanobodies acting as inhibitors of transport
Biochemistry. 2017; 56(30): 3962-3971. https://doi.org/10.1021/acs.biochem.7b00436
DORA PSI
Shahmoradian SH, Tsai EHR, Diaz A, Guizar-Sicairos M, Raabe J, Spycher L, et al.
Three-dimensional imaging of biological tissue by cryo X-ray ptychography
Scientific Reports. 2017; 7: 6291 (12 pp.). https://doi.org/10.1038/s41598-017-05587-4
DORA PSI
Sharma A, Sáez-Calvo G, Olieric N, de Asís Balaguer F, Barasoain I, Lamberth C, et al.
Quinolin-6-yloxyacetamides are microtubule destabilizing agents that bind to the colchicine site of tubulin
International Journal of Molecular Sciences. 2017; 18(7): 1336 (11 pp.). https://doi.org/10.3390/ijms18071336
DORA PSI
Standfuss J, Spence J
Serial crystallography at synchrotrons and X-ray lasers
IUCrJ. 2017; 4: 100-101. https://doi.org/10.1107/S2052252517001877
DORA PSI
Su J, Wang H, Wu K, Liu Z, Yin Q, Wang R, et al.
Neutravidin-mediated extraction of isolated small diameter single walled carbon nanotubes for bio-recognition
Journal of Nanoscience and Nanotechnology. 2017; 17(5): 3588-3596. https://doi.org/10.1166/jnn.2017.12860
DORA PSI
Sáez-Calvo G, Sharma A, de Asís Balaguer F, Barasoain I, Rodríguez-Salarichs J, Olieric N, et al.
Triazolopyrimidines are microtubule-stabilizing agents that bind the vinca inhibitor site of tubulin
Cell Chemical Biology. 2017; 24(6): 737-750. https://doi.org/10.1016/j.chembiol.2017.05.016
DORA PSI
Talip Z, Dressler R, David JC, Vockenhuber C, Müller Gubler E, Vögele A, et al.
Radiochemical determination of long-lived radionuclides in proton-irradiated heavy-metal targets: part I - Tantalum
Analytical Chemistry. 2017; 89(24): 13541-13549. https://doi.org/10.1021/acs.analchem.7b03952
DORA PSI
Tsai C-J, Standfuss J
Structural biology: signalling under the microscope
Nature. 2017; 546(7656): 36-37. https://doi.org/10.1038/nature22491
DORA PSI
Vercellino I, Rezabkova L, Olieric V, Polyhach Y, Weinert T, Kammerer RA, et al.
Role of the nucleotidyl cyclase helical domain in catalytically active dimer formation
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2017; 114(46): E9821-E9828. https://doi.org/10.1073/pnas.1712621114
DORA PSI
Wang R, Boleij M, Yin Q, Galjart N, Lin B, Yuan N, et al.
Purification of biotinylated proteins using single walled carbon nanotube-streptavidin complexes
Journal of Nanoscience and Nanotechnology. 2017; 17(2): 926-931. https://doi.org/10.1166/jnn.2017.12716
DORA PSI
Weinert T, Olieric N, Cheng R, Brünle S, James D, Ozerov D, et al.
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
Nature Communications. 2017; 8(1): 542 (11 pp.). https://doi.org/10.1038/s41467-017-00630-4
DORA PSI
Wu Y, Batyuk A, Honegger A, Brandl F, Mittl PRE, Plückthun A
Rigidly connected multispecific artificial binders with adjustable geometries
Scientific Reports. 2017; 7(1): 11217 (11 pp.). https://doi.org/10.1038/s41598-017-11472-x
DORA PSI
Yamamoto R, Obbineni JM, Alford LM, Ide T, Owa M, Hwang J, et al.
Chlamydomonas DYX1C1/PF23 is essential for axonemal assembly and proper morphology of inner dynein arms
PLoS Genetics. 2017; 13(10): e1006996 (21 pp.). https://doi.org/10.1371/journal.pgen.1006996
DORA PSI
Yin Q, Liu Z, Laroche F, Zhou X, Shao N, Lin B, et al.
A novel capturing method for quantification of extra-cellular nanovesicles
Journal of Nanoscience and Nanotechnology. 2017; 17(2): 908-913. https://doi.org/10.1166/jnn.2017.12631
DORA PSI
Zabel T, Geiger R, Marin E, Müller E, Diaz A, Bonzon C, et al.
Top-down method to introduce ultra-high elastic strain
Journal of Materials Research. 2017; 32(4): 726-736. https://doi.org/10.1557/jmr.2017.31
DORA PSI
Zaluzhnyy IA, Kurta RP, André A, Gorobtsov OY, Rose M, Skopintsev P, et al.
Quantifying angular correlations between the atomic lattice and the superlattice of nanocrystals assembled with directional linking
Nano Letters. 2017; 17(6): 3511-3517. https://doi.org/10.1021/acs.nanolett.7b00584
DORA PSI
Zhu X, Poghosyan E, Gopal R, Liu Y, Ciruelas KS, Maizy Y, et al.
General and specific promotion of flagellar assembly by a flagellar nucleoside diphosphate kinase
Molecular Biology of the Cell. 2017; 28(22): 3029-3042. https://doi.org/10.1091/mbc.E17-03-0156
DORA PSI
van Riel WE, Rai A, Bianchi S, Katrukha EA, Liu Q, Heck AJR, et al.
Kinesin-4 KIF21B is a potent microtubule pausing factor
eLife. 2017; 6: e24746 (30 pp.). https://doi.org/10.7554/eLife.24746
DORA PSI

Aroua S, Tiu EGV, Ishikawa T, Yamakoshi Y
Well-defined amphiphilic C₆₀-PEG conjugates: water-soluble and thermoresponsive materials
Helvetica Chimica Acta. 2016; 99(10): 805-813. https://doi.org/10.1002/hlca.201600171
DORA PSI
Benoit RM, Ostermeier C, Geiser M, Li JSZ, Widmer H, Auer M
Seamless insert-plasmid assembly at high efficiency and low cost
PLoS One. 2016; 11(4): e0153158 (13 pp.). https://doi.org/10.1371/journal.pone.0153158
DORA PSI
Bianchi S, van Riel WE, Kraatz SHW, Olieric N, Frey D, Katrukha EA, et al.
Structural basis for misregulation of kinesin KIF21A autoinhibition by CFEOM1 disease mutations
Scientific Reports. 2016; 6: 30668 (16 pp.). https://doi.org/10.1038/srep30668
DORA PSI
Burger D, Stihle M, Sharma A, Di Lello P, Benz J, D'Arcy B, et al.
Crystal structures of the human doublecortin C- and N-terminal domains in complex with specific antibodies
Journal of Biological Chemistry. 2016; 291(31): 16292-16306. https://doi.org/10.1074/jbc.M116.726547
DORA PSI
Capitani G, Duarte JM, Baskaran K, Bliven S, Somody JC
Understanding the fabric of protein crystals: computational classification of biological interfaces and crystal contacts
Bioinformatics. 2016; 32(4): 481-489. https://doi.org/10.1093/bioinformatics/btv622
DORA PSI
Christen P, Jaussi R, Benoit R
Biochemie und Molekularbiologie. Eine Einführung in 40 Lerneinheiten
Berlin, Heidelberg: Springer; 2016. https://doi.org/10.1007/978-3-662-46430-4
DORA PSI
Conder J, Forner-Cuenca A, Gubler EM, Gubler L, Novák P, Trabesinger S
Performance-enhancing asymmetric separator for lithium-sulfur batteries
ACS Applied Materials and Interfaces. 2016; 8(29): 18822-18831. https://doi.org/10.1021/acsami.6b04662
DORA PSI
Cypranowska CA, Yildiz A, Ishikawa T
Dyneins
In: Bradshaw RA, Stahl PD, eds. Encyclopedia of cell biology. Reference module in biomedical sciences. Amsterdam: Elsevier; 2016:620-636. https://doi.org/10.1016/B978-0-12-394447-4.20101-6
DORA PSI
Doodhi H, Prota AE, Rodríguez-García R, Xiao H, Custar DW, Bargsten K, et al.
Termination of protofilament elongation by eribulin induces lattice defects that promote microtubule catastrophes
Current Biology. 2016; 26(13): 1713-1721. https://doi.org/10.1016/j.cub.2016.04.053
DORA PSI
Ferre Llin L, Mirando F, Samarelli A, Odia A, Cecchi S, Etzelstorfer T, et al.
The use of silicon-germanium superlattices for thermoelectric devices and microfabricated generators
In: Murota J, Tillack B, Caymax M, Masini G, Harame DL, Miyazaki S, eds. SiGe, Ge, and related materials: materials, processing, and devices 7. Vol. 75. ECS transactions. Electrochemical Society; 2016:469-478. https://doi.org/10.1149/07508.0469ecst
DORA PSI
Foolen J, Shiu J-Y, Mitsi M, Zhang Y, Chen CS, Vogel V
Full-length fibronectin drives fibroblast accumulation at the surface of collagen microtissues during cell-induced tissue morphogenesis
PLoS One. 2016; 11(8): e0160369 (24 pp.). https://doi.org/10.1371/journal.pone.0160369
DORA PSI
Giese C, Eras J, Kern A, Schärer MA, Capitani G, Glockshuber R
Accelerating the association of the most stable protein–ligand complex by more than two orders of magnitude
Angewandte Chemie International Edition. 2016; 55(32): 9350-9355. https://doi.org/10.1002/anie.201603652
DORA PSI
Grillo E, Ravelli C, Corsini M, Ballmer-Hofer K, Zammataro L, Oreste P, et al.
Monomeric gremlin is a novel vascular endothelial growth factor receptor-2 antagonist
Oncotarget. 2016; 7(23): 35353-35368. https://doi.org/10.18632/oncotarget.9286
DORA PSI
Gruene T
[Review of the book Modern X-ray analysis on single crystals - a practical guide, 2nd ed., by P. Luger]
Crystallography Reviews. 2016; 22: 287-288. https://doi.org/10.1080/0889311X.2016.1237508
DORA PSI
Guesdon A, Bazile F, Buey RM, Mohan R, Monier S, García RR, et al.
EB1 interacts with outwardly curved and straight regions of the microtubule lattice
Nature Cell Biology. 2016; 18(10): 1102-1108. https://doi.org/10.1038/ncb3412
DORA PSI
Hilbert M, Noga A, Frey D, Hamel V, Guichard P, Kraatz SHW, et al.
SAS-6 engineering reveals interdependence between cartwheel and microtubules in determining centriole architecture
Nature Cell Biology. 2016; 18(4): 393-403. https://doi.org/10.1038/ncb3329
DORA PSI
Isabettini S, Liebi M, Kohlbrecher J, Ishikawa T, Windhab EJ, Fischer P, et al.
Tailoring bicelle morphology and thermal stability with lanthanide-chelating cholesterol conjugates
Langmuir. 2016; 32(35): 9005-9014. https://doi.org/10.1021/acs.langmuir.6b01968
DORA PSI
Ishikawa T
Electron tomography
In: Bradshaw RA, Stahl PD, eds. Encyclopedia of cell biology. Reference module in biomedical sciences. Amsterdam: Elsevier; 2016:22-31. https://doi.org/10.1016/B978-0-12-394447-4.20006-0
DORA PSI
Isogai S, Deupi X, Opitz C, Heydenreich FM, Tsai C-J, Brueckner F, et al.
Backbone NMR reveals allosteric signal transduction networks in the β₁-adrenergic receptor
Nature. 2016; 530(7589): 237-241. https://doi.org/10.1038/nature16577
DORA PSI
Jaeger K, Dworkowski F, Nogly P, Milne C, Wang M, Standfuss J
Serial millisecond crystallography of membrane proteins
In: Moraes I, ed. The next generation in membrane protein structure determination. Advances in experimental medicine and biology. Cham: Springer; 2016:137-149. https://doi.org/10.1007/978-3-319-35072-1_10
DORA PSI
Jamalia S, Ashtiania MM, Milić D
Synthesis of a new T-shaped heterobinuclear Pt⁰-Au^I complex [(t-Bu₃P)₂PtAu(PPh₃)]BF₄ from trinuclear gold cluster complex [(PPh₃)Au]₃(μ-O)BF₄
Scientia Iranica. 2016; 23(3): 1089-1094. https://doi.org/10.24200/sci.2016.3878
DORA PSI
Kevenaar JT, Bianchi S, van Spronsen M, Olieric N, Lipka J, Frias CP, et al.
Kinesin-binding protein controls microtubule dynamics and cargo trafficking by regulating kinesin motor activity
Current Biology. 2016; 26(7): 849-861. https://doi.org/10.1016/j.cub.2016.01.048
DORA PSI
Klima M, Tóth DJ, Hexnerova R, Baumlova A, Chalupska D, Tykvart J, et al.
Structural insights and in vitro reconstitution of membrane targeting and activation of human PI4KB by the ACBD3 protein
Scientific Reports. 2016; 6: 23641 (11 pp.). https://doi.org/10.1038/srep23641
DORA PSI
Kraatz S, Guichard P, Obbineni JM, Olieric N, Hatzopoulos GN, Hilbert M, et al.
The human centriolar protein CEP135 contains a two-stranded coiled-coil domain critical for microtubule binding
Structure. 2016; 24(8): 1358-1371. https://doi.org/10.1016/j.str.2016.06.011
DORA PSI
Leen EN, Sorgeloos F, Correia S, Chaudhry Y, Cannac F, Pastore C, et al.
A conserved interaction between a C-terminal motif in norovirus VPg and the HEAT-1 domain of eIF4G is essential for translation initiation
PLoS Pathogens. 2016; 12(1): e1005379 (34 pp.). https://doi.org/10.1371/journal.ppat.1005379
DORA PSI
Li X-D
2D membrane protein crystallography
In: Patterson BD, van Daalen M, eds. Whitebook on science with free electron lasers. PSI Bericht. Villigen PSI, Switzerland: Paul Scherrer Institut; 2016:60-67.
DORA PSI
Li X, Padhan N, Sjöström EO, Roche FP, Testini C, Honkura N, et al.
VEGFR2 pY949 signalling regulates adherens junction integrity and metastatic spread
Nature Communications. 2016; 7: 11017 (16 pp.). https://doi.org/10.1038/ncomms11017
DORA PSI
Luo J, Wärmländer SKTS, Gräslund A, Abrahams JP
Cross-interactions between the Alzheimer disease amyloid-β peptide and other amyloid proteins: a further aspect of the amyloid cascade hypothesis
Journal of Biological Chemistry. 2016; 291(32): 16485-16493. https://doi.org/10.1074/jbc.R116.714576
DORA PSI
Luo J, Wärmländer SKTS, Gräslund A, Abrahams JP
Reciprocal molecular interactions between the Aβ peptide linked to Alzheimer's disease and insulin linked to diabetes mellitus type II
ACS Chemical Neuroscience. 2016; 7(3): 269-274. https://doi.org/10.1021/acschemneuro.5b00325
DORA PSI
MacDonald JT, Kabasakal BV, Godding D, Kraatz S, Henderson L, Barber J, et al.
Synthetic beta-solenoid proteins with the fragmentfree computational design of a beta-hairpin extension
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2016; 113(37): 10346-10351. https://doi.org/10.1073/pnas.1525308113
DORA PSI
Manatschal C, Farcas A-M, Degen MS, Bayer M, Kumar A, Landgraf C, et al.
Molecular basis of Kar9-Bim1 complex function during mating and spindle positioning
Molecular Biology of the Cell. 2016; 27(23): 3729-3745. https://doi.org/10.1091/mbc.E16-07-0552
DORA PSI
Mansouri M, Bellon-Echeverria I, Rizk A, Ehsaei Z, Cianciolo Cosentino C, Silva CS, et al.
Highly efficient baculovirus-mediated multigene delivery in primary cells
Nature Communications. 2016; 7: 11529 (13 pp.). https://doi.org/10.1038/ncomms11529
DORA PSI
Mohacsi I, Vartiainen I, Guizar-Sicairos M, Karvinen P, Guzenko VA, Müller E, et al.
Fabrication and characterization of highefficiency double-sided blazed X-ray optics
Optics Letters. 2016; 41(2): 281-284. https://doi.org/10.1364/OL.41.000281
DORA PSI
Nango E, Royant A, Kubo M, Nakane T, Wickstrand C, Kimura T, et al.
A three-dimensional movie of structural changes in bacteriorhodopsin
Science. 2016; 354(6319): 1552-1557. https://doi.org/10.1126/science.aaH3497
DORA PSI
Nogly P, Panneels V, Nelson G, Gati C, Kimura T, Milne C, et al.
Lipidic cubic phase injector is a viable crystal delivery system for time-resolved serial crystallography
Nature Communications. 2016; 7: 12314 (9 pp.). https://doi.org/10.1038/ncomms12314
DORA PSI
Olieric V, Weinert T, Finke AD, Anders C, Li D, Olieric N, et al.
Data-collection strategy for challenging native SAD phasing
Acta Crystallographica Section D: Structural Biology. 2016; 72(3): 421-429. https://doi.org/10.1107/S2059798315024110
DORA PSI
Peterhans C, Lally CCM, Ostermaier MK, Sommer ME, Standfuss J
Functional map of arrestin binding to phosphorylated opsin, with and without agonist
Scientific Reports. 2016; 6: 28686 (14 pp.). https://doi.org/10.1038/srep28686
DORA PSI
Pfister B, Sánchez-Ferrer A, Diaz A, Lu K, Otto C, Holler M, et al.
Recreating the synthesis of starch granules in yeast
eLife. 2016; 5: e15552 (29 pp.). https://doi.org/10.7554/eLife.15552
DORA PSI
Prota AE, Setter J, Waight AB, Bargsten K, Murga J, Diaz JF, et al.
Pironetin binds covalently to αCys316 and perturbs a major loop and helix of α-tubulin to inhibit microtubule formation
Journal of Molecular Biology. 2016; 428(15): 2981-2988. https://doi.org/10.1016/j.jmb.2016.06.023
DORA PSI
Radaelli G, Gutiérrez D, Qian M, Fina I, Sánchez F, Baldrati L, et al.
Strain-controlled responsiveness of slave half-doped manganite La_0.5Sr_0.5MnO₃ layers inserted in BaTiO₃ ferroelectric tunnel junctions
Advanced Electronic Materials. 2016; 2(12): 1600368 (7 pp.). https://doi.org/10.1002/aelm.201600368
DORA PSI
Rezabkova L, Kraatz SHW, Akhmanova A, Steinmetz MO, Kammerer RA
Biophysical and structural characterization of the centriolar protein CEP104 interaction network
Journal of Biological Chemistry. 2016; 291(35): 18496-18504. https://doi.org/10.1074/jbc.M116.739771
DORA PSI
Sarabipour S, Ballmer-Hofer K, Hristova K
VEGFR-2 conformational switch in response to ligand binding
eLife. 2016; 5: e13876 (23 pp.). https://doi.org/10.7554/eLife.13876
DORA PSI
Sharma A, Aher A, Dynes NJ, Frey D, Katrukha EA, Jaussi R, et al.
Centriolar CPAP/SAS-4 imparts slow processive microtubule growth
Developmental Cell. 2016; 37(4): 362-376. https://doi.org/10.1016/j.devcel.2016.04.024
DORA PSI
Singhal A, Guo Y, Matkovic M, Schertler G, Deupi X, Yan ECY, et al.
Structural role of the T94I rhodopsin mutation in congenital stationary night blindness
EMBO Reports. 2016; 17(10): 1431-1440. https://doi.org/10.15252/embr.201642671
DORA PSI
Tanasescu R, Lanz MA, Mueller D, Tassler S, Ishikawa T, Reiter R, et al.
Vesicle origami and the influence of cholesterol on lipid packing
Langmuir. 2016; 32(19): 4896-4903. https://doi.org/10.1021/acs.langmuir.6b01143
DORA PSI
Thomsen ARB, Plouffe B, Cahill III TJ, Shukla AK, Tarrasch JT, Dosey AM, et al.
GPCR-G protein-β-arrestin super-complex mediates sustained G protein signaling
Cell. 2016; 166(4): 907-919. https://doi.org/10.1016/j.cell.2016.07.004
DORA PSI
Tiiman A, Luo J, Wallin C, Olsson L, Lindgren J, Jarvet J, et al.
Specific binding of Cu(II) ions to amyloid-beta peptides bound to aggregation-inhibiting molecules or SDS micelles creates complexes that generate radical oxygen species
Journal of Alzheimer's Disease. 2016; 54(3): 971-982. https://doi.org/10.3233/JAD-160427
DORA PSI
Trigili C, Barasoain I, Sánchez-Murcia PA, Bargsten K, Redondo-Horcajo M, Nogales A, et al.
Structural determinants of the dictyostatin chemotype for tubulin binding affinity and antitumor activity against taxane- and epothilone-resistant cancer cells
ACS Omega. 2016; 1(6): 1192-1204. https://doi.org/10.1021/acsomega.6b00317
DORA PSI
Venkatakrishnan AJ, Deupi X, Lebon G, Heydenreich FM, Flock T, Miljus T, et al.
Diverse activation pathways in class A GPCRs converge near the G-protein-coupling region
Nature. 2016; 536(7617): 484-487. https://doi.org/10.1038/nature19107
DORA PSI
Waight AB, Bargsten K, Doronina S, Steinmetz MO, Sussman D, Prota AE
Structural basis of microtubule destabilization by potent auristatin anti-mitotics
PLoS One. 2016; 11(8): e0160890 (14 pp.). https://doi.org/10.1371/journal.pone.0160890
DORA PSI
Wallin C, Kulkarni YS, Abelein A, Jarvet J, Liao Q, Strodel B, et al.
Characterization of Mn(II) ion binding to the amyloid-β peptide in Alzheimer's disease
Journal of Trace Elements in Medicine and Biology. 2016; 38: 183-193. https://doi.org/10.1016/j.jtemb.2016.03.009
DORA PSI
White TA, Barty A, Liu W, Ishchenko A, Zhang H, Gati C, et al.
Serial femtosecond crystallography datasets from G protein-coupled receptors
Scientific Data. 2016; 3: 160057 (9 pp.). https://doi.org/10.1038/sdata.2016.57
DORA PSI
Wieczorek M, Tcherkezian J, Bernier C, Prota AE, Chaaban S, Rolland Y, et al.
The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity
Science Translational Medicine. 2016; 8(365): 365ra159 (14 pp.). https://doi.org/10.1126/scitranslmed.aag1093
DORA PSI
van Genderen E, Clabbers MTB, Das PP, Stewart A, Nederlof I, Barentsen KC, et al.
Ab initio structure determination of nanocrystals of organic pharmaceutical compounds by electron diffraction at room temperature using a Timepix quantum area direct electron detector
Acta Crystallographica Section A: Foundations and Advances. 2016; 72: 236-242. https://doi.org/10.1107/S2053273315022500
DORA PSI

Abela E, Missimer JH, Federspiel A, Seiler A, Hess CW, Sturzenegger M, et al.
A thalamic-fronto-parietal structural covariance network emerging in the course of recovery from hand paresis after ischemic stroke
Frontiers in Neurology. 2015; 6: 211 (14 pp.). https://doi.org/10.3389/fneur.2015.00211
DORA PSI
Abela E, Seiler A, Missimer JH, Federspiel A, Hess CW, Sturzenegger M, et al.
Grey matter volumetric changes related to recovery from hand paresis after cortical sensorimotor stroke
Brain Structure and Function. 2015; 220(5): 2533-2550. https://doi.org/10.1007/s00429-014-0804-y
DORA PSI
Akhmanova A, Steinmetz MO
Control of microtubule organization and dynamics: two ends in the limelight
Nature Reviews Molecular Cell Biology. 2015; 16(12): 711-726. https://doi.org/10.1038/nrm4084
DORA PSI
Aroua S, Tiu EGV, Ayer M, Ishikawa T, Yamakoshi Y
RAFT synthesis of poly(vinylpyrrolidone) amine and preparation of a water-soluble C60-PVP conjugate
Polymer Chemistry. 2015; 6(14): 2616-2619. https://doi.org/10.1039/c4py01333f
DORA PSI
Astegno A, Capitani G, Dominici P
Functional roles of the hexamer organization of plant glutamate decarboxylase
Biochimica et Biophysica Acta: Proteins and Proteomics. 2015; 1854(9): 1229-1237. https://doi.org/10.1016/j.bbapap.2015.01.001
DORA PSI
Benoit RM, Frey D, Wieser MM, Thieltges KM, Jaussi R, Capitani G, et al.
Structure of the BoNT/A1 - Receptor complex
Toxicon. 2015; 107(Part A): 25-31. https://doi.org/10.1016/j.toxicon.2015.08.002
DORA PSI
Christen M, Marcaida MJ, Lamprakis C, Aeschimann W, Vaithilingam J, Schneider P, et al.
Structural insights on cholesterol endosynthesis: binding of squalene and 2,3-oxidosqualene to supernatant protein factor
Journal of Structural Biology. 2015; 190(3): 261-270. https://doi.org/10.1016/j.jsb.2015.05.001
DORA PSI
Dais C, Mussler G, Fromherz T, Müller E, Solak HH, Grützmacher D
SiGe quantum dot crystals with periods down to 35 nm
Nanotechnology. 2015; 26(25): 255302 (6 pp.). https://doi.org/10.1088/0957-4484/26/25/255302
DORA PSI
Diaz A, Malkova B, Holler M, Guizar-Sicairos M, Lima E, Panneels V, et al.
Three-dimensional mass density mapping of cellular ultrastructure by ptychographic X-ray nanotomography
Journal of Structural Biology. 2015; 192(3): 461-469. https://doi.org/10.1016/j.jsb.2015.10.008
DORA PSI
Dong J, Zhao H, Zhou T, Spiliotopoulos D, Rajendran C, Li X-D, et al.
Structural analysis of the binding of type I, I_1/2, and II inhibitors to Eph tyrosine kinases
ACS Medicinal Chemistry Letters. 2015; 6(1): 79-83. https://doi.org/10.1021/ml500355x
DORA PSI
Donnelly C, Guizar-Sicairos M, Scagnoli V, Holler M, Huthwelker T, Menzel A, et al.
Element-specific X-ray phase tomography of 3D structures at the nanoscale
Physical Review Letters. 2015; 114(11): 115501 (5 pp.). https://doi.org/10.1103/PhysRevLett.114.115501
DORA PSI
Feld GK, Heymann M, Benner WH, Pardini T, Tsai C-J, Boutet S, et al.
Low-Z polymer sample supports for fixed-target serial femtosecond X-ray crystallography
Journal of Applied Crystallography. 2015; 48: 1072-1079. https://doi.org/10.1107/S1600576715010493
DORA PSI
Flock T, Ravarani CNJ, Sun D, Venkatakrishnan AJ, Kayikci M, Tate CG, et al.
Universal allosteric mechanism for Gα activation by GPCRs
Nature. 2015; 524: 173-179. https://doi.org/10.1038/nature14663
DORA PSI
Fodor D, Ishikawa T, Krumeich F, van Bokhoven JA
Synthesis of single crystal nanoreactor materials with multiple catalytic functions by incipient wetness impregnation and ion exchange
Advanced Materials. 2015; 27(11): 1919-1923. https://doi.org/10.1002/adma.201404628
DORA PSI
Geertsma ER, Chang Y-N, Shaik FR, Neldner Y, Pardon E, Steyaert J, et al.
Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family
Nature Structural and Molecular Biology. 2015; 22(10): 803-808. https://doi.org/10.1038/nsmb.3091
DORA PSI
He X, Robertson N, Jazayeri A, Geroni Gasperina A, Schertler G, Li X
Large scale expression and purification of the rat 5-HT_2c receptor
Protein Expression and Purification. 2015; 106: 1-9. https://doi.org/10.1016/j.pep.2014.10.010
DORA PSI
Heydenreich FM, Vuckovic Z, Matkovic M, Veprintsev DB
Stabilization of G protein-coupled receptors by point mutations
Frontiers in Pharmacology. 2015; 6: 82 (15 pp.). https://doi.org/10.3389/fphar.2015.00082
DORA PSI
Hofbauer S, Brito JA, Mulchande J, Nogly P, Pessanha M, Moreira R, et al.
Stabilization of porcine pancreatic elastase crystals by glutaraldehyde cross-linking
Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2015; 71: 1346-1351. https://doi.org/10.1107/S2053230X15017045
DORA PSI
Hulse RP, Beazley-Long N, Ved N, Bestall SM, Riaz H, Singhal P, et al.
Vascular endothelial growth factor-A₁₆₅b prevents diabetic neuropathic pain and sensory neuronal degeneration
Clinical Science. 2015; 129(8): 741-756. https://doi.org/10.1042/CS20150124
DORA PSI
Inoue M, Li X
Highly active and stable oxaloacetate decarboxylase Na⁺ pump complex for structural analysis
Protein Expression and Purification. 2015; 115: 34-38. https://doi.org/10.1016/j.pep.2015.05.008
DORA PSI
Ishikawa T
Cryo-electron tomography of motile cilia and flagella
Cilia. 2015; 4(Suppl. 1): 3 (20 pp.). https://doi.org/10.1186/s13630-014-0012-7
DORA PSI
Janke C, Steinmetz MO
Optochemistry to control the microtubule cytoskeleton
EMBO Journal. 2015; 34(16): 2114-2116. https://doi.org/10.15252/embj.201592415
DORA PSI
Jurić M, Pajić D, Žilić D, Rakvin B, Milić D, Planinić P
Synthesis, crystal structures and magnetic properties of the oxalate-bridged single Cu^IICu^II and cocrystallized Cu^IIZn^II systems. Three species (CuCu, CuZn, ZnZn) in the crystalline lattice
Polyhedron. 2015; 98: 26-34. https://doi.org/10.1016/j.poly.2015.05.034
DORA PSI
Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, et al.
Crystal structure of rhodopsin bound to arrestin by femtosecond X-ray laser
Nature. 2015; 523: 561-567. https://doi.org/10.1038/nature14656
DORA PSI
Li X-D, Winkler FK, Huergo LF
How does the DraG–P_II complex regulate nitrogenase activity in Azospirillum brasilense?
In: de Bruijn FJ, ed. Biological nitrogen fixation. Hoboken, New Jersey: Wiley; 2015:139-145. https://doi.org/10.1002/9781119053095.ch13
DORA PSI
Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Walde P, Windhab EJ, et al.
Design of magnetically responsive phospholipid bicelles towards switchable optical hydrogels
Swiss Neutron News. https://sgn.web.psi.ch/sgn/snn.html. Published 2015. Accessed no date.
DORA PSI
Maheshwari A, Obbineni JM, Bui KH, Shibata K, Toyoshima YY, Ishikawa T
α- and β-Tubulin Lattice of the Axonemal Microtubule Doublet and Binding Proteins Revealed by Single Particle Cryo-Electron Microscopy and Tomography
Structure. 2015; 23(9): 1584-1595. https://doi.org/10.1016/j.str.2015.06.017
DORA PSI
Mattle D, Singhal A, Schmid G, Dawson R, Standfuss J
Mammalian expression, purification, and crystallization of rhodopsin variants
In: Jastrzebska B, ed. Rhodopsin. Methods and protocols. Methods in molecular biology. New York: Humana Press; 2015:39-54. https://doi.org/10.1007/978-1-4939-2330-4_3
DORA PSI
McPeak KM, van Engers CD, Bianchi S, Rossinelli A, Poulikakos LV, Bernard L, et al.
Ultraviolet plasmonic chirality from colloidal aluminum nanoparticles exhibiting charge-selective protein detection
Advanced Materials. 2015; 27(40): 6244-6250. https://doi.org/10.1002/adma.201503493
DORA PSI
Milic D, Veprintsev DB
Large-scale production and protein engineering of G protein-coupled receptors for structural studies
Frontiers in Pharmacology. 2015; 6: 66 (24 pp.). https://doi.org/10.3389/fphar.2015.00066
DORA PSI
Mirza H, Kumar A, Craiglow BG, Zhou J, Saraceni C, Torbeck R, et al.
Mutations affecting keratin 10 surface-exposed residues highlight the structural basis of phenotypic variation in epidermolytic ichthyosis
Journal of Investigative Dermatology. 2015; 135(12): 3041-3050. https://doi.org/10.1038/jid.2015.284
DORA PSI
Mitsi M, Handschin S, Gerber I, Schwartländer R, Klotzsch E, Wepf R, et al.
The ultrastructure of fibronectin fibers pulled from a protein monolayer at the air-liquid interface and the mechanism of the sheet-to-fiber transition
Biomaterials. 2015; 36: 66-79. https://doi.org/10.1016/j.biomaterials.2014.08.012
DORA PSI
Mohacsi I, Vartiainen I, Guizar-Sicairos M, Karvinen P, Guzenko VA, Müller E, et al.
High resolution double-sided diffractive optics for hard X-ray microscopy
Optics Express. 2015; 23(2): 776-786. https://doi.org/10.1364/OE.23.000776
DORA PSI
Nogly P, Standfuss J
Light-driven Na⁺ pumps as next-generation inhibitory optogenetic tools
Nature Structural and Molecular Biology. 2015; 22(5): 351-353. https://doi.org/10.1038/nsmb.3017
DORA PSI
Nogly P, James D, Wang D, White TA, Zatsepin N, Shilova A, et al.
Lipidic cubic phase serial millisecond crystallography using synchrotron radiation
IUCrJ. 2015; 2: 168-176. https://doi.org/10.1107/S2052252514026487
DORA PSI
Oltean S, Qiu Y, Ferguson JK, Stevens M, Neal C, Russell A, et al.
Vascular endothelial growth factor-A₁₆₅b is protective and restores endothelial glycocalyx in diabetic nephropathy
Journal of the American Society of Nephrology. 2015; 26(8): 1889-1904. https://doi.org/10.1681/ASN.2014040350
DORA PSI
Panneels V, Wu W, Tsai C-J, Nogly P, Rheinberger J, Jaeger K, et al.
Time-resolved structural studies with serial crystallography: a new light on retinal proteins
Structural Dynamics. 2015; 2(4): 041718 (8 pp.). https://doi.org/10.1063/1.4922774
DORA PSI
Rizk A, Mansouri M, Ballmer-Hofer K, Berger P
Subcellular object quantification with Squassh3C and SquasshAnalyst
BioTechniques. 2015; 59(5): 309-311. https://doi.org/10.2144/000114352
DORA PSI
Roderer DJA, Schärer MA, Rubini M, Glockshuber R
Acceleration of protein folding by four orders of magnitude through a single amino acid substitution
Scientific Reports. 2015; 5: 11840 (16 pp.). https://doi.org/10.1038/srep11840
DORA PSI
Rosenthal RG, Vögeli B, Quade N, Capitani G, Kiefer P, Vorholt JA, et al.
The use of ene adducts to study and engineer enoyl-thioester reductases
Nature Chemical Biology. 2015; 11(6): 398-400. https://doi.org/10.1038/nchembio.1794
DORA PSI
Standfuss J
Viral chemokine mimicry. How do viruses trick the human immune system?
Science. 2015; 347(6226): 1071-1072. https://doi.org/10.1126/science.aaa7998
DORA PSI
Sun D, Flock T, Deupi X, Maeda S, Matkovic M, Mendieta S, et al.
Probing Gα_i1 protein activation at single-amino acid resolution
Nature Structural and Molecular Biology. 2015; 22(9): 686-694. https://doi.org/10.1038/nsmb.3070
DORA PSI
Weinberger A, Tanasescu R, Stefaniu C, Fedotenko LA, Favarger F, Ishikawa T, et al.
Bilayer properties of 1,3-diamidophospholipids
Langmuir. 2015; 31(6): 1879-1884. https://doi.org/10.1021/la5041745
DORA PSI
Weinert T, Olieric V, Waltersperger S, Panepucci E, Chen L, Zhang H, et al.
Fast native-SAD phasing for routine macromolecular structure determination
Nature Methods. 2015; 12(2): 131-133. https://doi.org/10.1038/nmeth.3211
DORA PSI
Wu W, Nogly P, Rheinberger J, Kick LM, Gati C, Nelson G, et al.
Batch crystallization of rhodopsin for structural dynamics using an X-ray free-electron laser
Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 2015; 71: 856-860. https://doi.org/10.1107/S2053230X15009966
DORA PSI
Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, et al.
A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation
PLoS One. 2015; 10(5): e0126420 (30 pp.). https://doi.org/10.1371/journal.pone.0126420
DORA PSI

Li Y, Lu SH-J, Tsai C-J, Bohm C, Qamar S, Dodd RB, et al.
Structural interactions between inhibitor and substrate docking sites give insight into mechanisms of human PS1 complexes
Structure. 2014; 22(1): 125-135. https://doi.org/10.1016/j.str.2013.09.018
DORA PSI

Abicht HK, Schärer MA, Quade N, Ledermann R, Mohorko E, Capitani G, et al.
How periplasmic thioredoxin TlpA reduces bacterial copper chaperone ScoI and cytochrome oxidase subunit II (CoxB) prior to metallation
Journal of Biological Chemistry. 2014; 289(47): 32431-32444. https://doi.org/10.1074/jbc.M114.607127
DORA PSI
Alfieri A, Ong ACM, Kammerer RA, Solanky T, Bate S, Tasab M, et al.
Angiopoietin-1 regulates microvascular reactivity and protects the microcirculation during acute endothelial dysfunction: role of eNOS and VE-cadherin
Pharmacological Research. 2014; 80: 43-51. https://doi.org/10.1016/j.phrs.2013.12.008
DORA PSI
Andersson M, Mattle D, Sitsel O, Klymchuk T, Nielsen AM, Møller LB, et al.
Copper-transporting P-type ATPases use a unique ion-release pathway
Nature Structural and Molecular Biology. 2014; 21(1): 43-48. https://doi.org/10.1038/nsmb.2721
DORA PSI
Angelaccio S, Dworkowski F, Di Bello A, Milano T, Capitani G, Pascarella S
Conformational transitions driven by pyridoxal-5′-phosphate uptake in the psychrophilic serine hydroxymethyltransferase from Psychromonas ingrahamii
Proteins. 2014; 82(10): 2831-2841. https://doi.org/10.1002/prot.24646
DORA PSI
Baskaran K, Duarte JM, Biyani N, Bliven S, Capitani G
A PDB-wide, evolution-based assessment of protein-protein interfaces
BMC Structural Biology. 2014; 14: 22 (11 pp.). https://doi.org/10.1186/s12900-014-0022-0
DORA PSI
Benoit RM, Frey D, Hilbert M, Kevenaar JT, Wieser MM, Stirnimann CU, et al.
Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A
Nature. 2014; 505(7481): 108-111. https://doi.org/10.1038/nature12732
DORA PSI
Campagne S, Marsh ME, Capitani G, Vorholt JA, Allain FH-T
Structural basis for -10 promoter element melting by environmentally induced sigma factors
Nature Structural and Molecular Biology. 2014; 21(3): 269-276. https://doi.org/10.1038/nsmb.2777
DORA PSI
Czaja K, Borer AS, Schmied L, Terszowski G, Stern M, Gonzalez A
A comprehensive analysis of the binding of anti-KIR antibodies to activating KIRs
Genes and Immunity. 2014; 15: 33-37. https://doi.org/10.1038/gene.2013.58
DORA PSI
De Groot GW, Demarche S, Santonicola MG, Tiefenauer L, Vancso GJ
Smart polymer brush nanostructures guide the self-assembly of pore-spanning lipid bilayers with integrated membrane proteins
Nanoscale. 2014; 6(4): 2228-2237. https://doi.org/10.1039/c3nr05356c
DORA PSI
Duellberg C, Trokter M, Jha R, Sen I, Steinmetz MO, Surrey T
Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein
Nature Cell Biology. 2014; 16(8): 804-811. https://doi.org/10.1038/ncb2999
DORA PSI
Frank M, Carlson DB, Hunter MS, Williams GJ, Messerschmidt M, Zatsepin NA, et al.
Femtosecond X-ray diffraction from two-dimensional protein crystals
IUCrJ. 2014; 1: 95-100. https://doi.org/10.1107/S2052252514001444
DORA PSI
Hassaine G, Deluz C, Grasso L, Wyss R, Tol MB, Hovius R, et al.
X-ray structure of the mouse serotonin 5-HT₃ receptor
Nature. 2014; 512(7514): 276-281. https://doi.org/10.1038/nature13552
DORA PSI
Hulse RP, Beazley-Long N, Hua J, Kennedy H, Prager J, Bevan H, et al.
Regulation of alternative VEGF-A mRNA splicing is a therapeutic target for analgesia
Neurobiology of Disease. 2014; 71: 245-259. https://doi.org/10.1016/j.nbd.2014.08.012
DORA PSI
Hyde CAC, Berger P, Ballmer-Hofer K
Finding new partnerships: The function of individual extracellular receptor domains in angiogenic signalling by VEGF receptors
In: Feige J-J, Pagès G, Soncin F, eds. Molecular mechanisms of angiogenesis. From ontogenesis to oncogenesis. Paris: Springer; 2014:47-75. https://doi.org/10.1007/978-2-8178-0466-8_3
DORA PSI
Ishikawa T
Protein tagging reveals new insights into signaling in flagella
Journal of Cell Biology. 2014; 204(5): 631-633. https://doi.org/10.1083/jcb.201401142
DORA PSI
Jayachandran R, Liu X, BoseDasgupta S, Müller P, Zhang C-L, Moshous D, et al.
Coronin 1 regulates cognition and behavior through modulation of cAMP/Protein kinase A signaling
PLoS Biology. 2014; 12(3): e1001820 (21 pp.). https://doi.org/10.1371/journal.pbio.1001820
DORA PSI
Kammerer RA, Benoit RM
Botulinum neurotoxins: new questions arising from structural biology
Trends in Biochemical Sciences. 2014; 39(11): 517-526. https://doi.org/10.1016/j.tibs.2014.08.009
DORA PSI
Karagöz GE, Duarte AMS, Akoury E, Ippel H, Biernat J, Morán Luengo T, et al.
Hsp90-Tau complex reveals molecular basis for specificity in chaperone action
Cell. 2014; 156(5): 963-974. https://doi.org/10.1016/j.cell.2014.01.037
DORA PSI
Khan MA, Rupp VM, Orpinell M, Hussain MS, Altmüller J, Steinmetz MO, et al.
A missense mutation in the PISA domain of HsSAS-6 causes autosomal recessive primary microcephaly in a large consanguineous Pakistani family
Human Molecular Genetics. 2014; 23(22): 5940-5949. https://doi.org/10.1093/hmg/ddu318
DORA PSI
Koch S, van Meeteren LA, Morin E, Testini C, Weström S, Björkelund H, et al.
NRP1 presented in trans to the endothelium arrests VEGFR2 endocytosis, preventing angiogenic signaling and tumor initiation
Developmental Cell. 2014; 28(6): 633-646. https://doi.org/10.1016/j.devcel.2014.02.010
DORA PSI
Korkhov VM, Mireku SA, Veprintsev DB, Locher KP
Structure of AMP-PNP-bound BtuCD and mechanism of ATP-powered vitamin B12 transport by BtuCD-F
Nature Structural and Molecular Biology. 2014; 21(12): 1097-1099. https://doi.org/10.1038/nsmb.2918
DORA PSI
Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, et al.
Magnetically enhanced bicelles delivering switchable anisotropy in optical gels
ACS Applied Materials and Interfaces. 2014; 6(2): 1100-1105. https://doi.org/10.1021/am4046469
DORA PSI
López MP, Huber F, Grigoriev I, Steinmetz MO, Akhmanova A, Koenderink GH, et al.
Actin-microtubule coordination at growing microtubule ends
Nature Communications. 2014; 5: 4778 (9 pp.). https://doi.org/10.1038/ncomms5778
DORA PSI
Maeda S, Sun D, Singhal A, Foggetta M, Schmid G, Standfuss J, et al.
Crystallization scale preparation of a stable GPCR signaling complex between constitutively active rhodopsin and G-protein
PLoS One. 2014; 9(6): e98714 (11 pp.). https://doi.org/10.1371/journal.pone.0098714
DORA PSI
Malito E, Biancucci M, Faleri A, Ferlenghi I, Scarselli M, Maruggi G, et al.
Structure of the meningococcal vaccine antigen nada and epitope mapping of a bactericidal antibody
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(48): 17128-17133. https://doi.org/10.1073/pnas.1419686111
DORA PSI
Manni S, Kisko K, Schleier T, Missimer J, Ballmer-Hofer K
Functional and structural characterization of the kinase insert and the carboxy terminal domain in VEGF receptor 2 activation
FASEB Journal. 2014; 28(11): 4914-4923. https://doi.org/10.1096/fj.14-256206
DORA PSI
Manni S, Mineev KS, Usmanova D, Lyukmanova EN, Shulepko MA, Kirpichnikov MP, et al.
Structural and functional characterization of alternative transmembrane domain conformations in VEGF receptor 2 activation
Structure. 2014; 22(8): 1077-1089. https://doi.org/10.1016/j.str.2014.05.010
DORA PSI
Mansouri M, Berger P
Strategies for multigene expression in eukaryotic cells
Plasmid. 2014; 75: 12-17. https://doi.org/10.1016/j.plasmid.2014.07.001
DORA PSI
Moure VR, Costa FF, Cruz LM, Pedrosa FO, Souza EM, Li X-D, et al.
Regulation of nitrogenase by reversible mono-ADP-ribosylation
In: Koch-Nolte F, ed. Endogenous ADP-ribosylation. Current topics in microbiology and immunology. Cham: Springer; 2014:89-106. https://doi.org/10.1007/82_2014_380
DORA PSI
Nogueira ES, Schleier T, Dürrenberger M, Ballmer-Hofer K, Ward TR, Jaussi R
High-level secretion of recombinant full-length streptavidin in Pichia pastoris and its application to enantioselective catalysis
Protein Expression and Purification. 2014; 93: 54-62. https://doi.org/10.1016/j.pep.2013.10.015
DORA PSI
Ostermaier MK, Peterhans C, Jaussi R, Deupi X, Standfuss J
Functional map of arrestin-1 at single amino acid resolution
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(5): 1825-1830. https://doi.org/10.1073/pnas.1319402111
DORA PSI
Ostermaier MK, Schertler GFX, Standfuss J
Molecular mechanism of phosphorylation-dependent arrestin activation
Current Opinion in Structural Biology. 2014; 29: 143-151. https://doi.org/10.1016/j.sbi.2014.07.006
DORA PSI
Pedrini B, Tsai C-J, Capitani G, Padeste C, Hunter MS, Zatsepin NA, et al.
7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source
Philosophical Transactions of the Royal Society B: Biological Sciences. 2014; 369(1647): 20130500 (5 pp.). https://doi.org/10.1098/rstb.2013.0500
DORA PSI
Pfreundschuh M, Alsteens D, Hilbert M, Steinmetz MO, Müller DJ
Localizing chemical groups while imaging single native proteins by high-resolution atomic force microscopy
Nano Letters. 2014; 14(5): 2957-2964. https://doi.org/10.1021/nl5012905
DORA PSI
Prota AE, Bargsten K, Diaz JF, Marsh M, Cuevas C, Liniger M, et al.
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2014; 111(38): 13817-13821. https://doi.org/10.1073/pnas.1408124111
DORA PSI
Prota AE, Bargsten K, Northcote PT, Marsh M, Altmann K-H, Miller JH, et al.
Structural basis of microtubule stabilization by laulimalide and peloruside A
Angewandte Chemie International Edition. 2014; 53(6): 1621-1625. https://doi.org/10.1002/anie.201307749
DORA PSI
Prota AE, Danel F, Bachmann F, Bargsten K, Buey RM, Pohlmann J, et al.
The novel microtubule-destabilizing drug BAL27862 binds to the colchicine site of tubulin with distinct effects on microtubule organization
Journal of Molecular Biology. 2014; 426(8): 1848-1860. https://doi.org/10.1016/j.jmb.2014.02.005
DORA PSI
Rizk A, Paul G, Incardona P, Bugarski M, Mansouri M, Niemann A, et al.
Segmentation and quantification of subcellular structures in fluorescence microscopy images using Squassh
Nature Protocols. 2014; 9(3): 586-596. https://doi.org/10.1038/nprot.2014.037
DORA PSI
Simmons KJ, Jackson SM, Brueckner F, Patching SG, Beckstein O, Ivanova E, et al.
Molecular mechanism of ligand recognition by membrane transport protein, Mhp1
EMBO Journal. 2014; 33(16): 1831-1844. https://doi.org/10.15252/embj.201387557
DORA PSI
Stroud MJ, Nazgiewicz A, McKenzie EA, Wang Y, Kammerer RA, Ballestrem C
GAS2-like proteins mediate communication between microtubules and actin through interactions with end-binding proteins
Journal of Cell Science. 2014; 127(12): 2672-2682. https://doi.org/10.1242/jcs.140558
DORA PSI
Truan D, Bjelić S, Li X-D, Winkler FK
Structure and thermodynamics of effector molecule binding to the nitrogen signal transduction P_II protein GlnZ from Azospirillum brasilense
Journal of Molecular Biology. 2014; 426(15): 2783-2799. https://doi.org/10.1016/j.jmb.2014.05.008
DORA PSI
Ueno H, Bui KH, Ishikawa T, Imai Y, Yamaguchi T, Ishikawa T
Structure of dimeric axonemal dynein in cilia suggests an alternative mechanism of force generation
Cytoskeleton. 2014; 71(7): 412-422. https://doi.org/10.1002/cm.21180
DORA PSI
Von Känel H, Isa F, Falub CV, Barthazy EJ, Müller E, Chrastina D, et al.
Three-dimensional epitaxial Si_1-xGe_x, Ge and SiC crystals on deeply patterned Si substrates
In: Vincent B, Ogura A, Harame D, Caymax M, Miyazaki S, Niu G, et al., eds. SiGe, Ge, and related compounds: materials, processing and devices symposium. Vol. 64. ECS transactions. Electrochemical Society Inc.; 2014:631-648. https://doi.org/10.1149/06406.0631ecst
DORA PSI
Weber S, Stirnimann CU, Wieser M, Frey D, Meier R, Engelhardt S, et al.
A type IV translocated Legionella cysteine phytase counteracts intracellular growth restriction by phytate
Journal of Biological Chemistry. 2014; 289(49): 34175-34188. https://doi.org/10.1074/jbc.M114.592568
DORA PSI
Weber H, Müller D, Müller M, Ortiz A, Birkle M, Umber S, et al.
Cell lines expressing recombinant transmembrane domain-activated receptor kinases as tools for drug discovery
Journal of Biomolecular Screening. 2014; 19(10): 1350-1361. https://doi.org/10.1177/1087057114552414
DORA PSI
Wiest R, Abela E, Missimer J, Schroth G, Hess CW, Sturzenegger M, et al.
Interhemispheric cerebral blood flow balance during recovery of motor hand function after ischemic stroke-a longitudinal MRI study using arterial spin labeling perfusion
PLoS One. 2014; 9(9): e106327 (10 pp.). https://doi.org/10.1371/journal.pone.0106327
DORA PSI
Žilić D, Rakvin B, Milić D, Pajić D, Łilović I, Cametti M, et al.
Crystal structures and magnetic properties of a set of dihalo-bridged oxalamidato copper(ii) dimers
Dalton Transactions. 2014; 43(31): 11877-11887. https://doi.org/10.1039/c4dt00925h
DORA PSI

Bjelić S, Wieser M, Frey D, Stirnimann CU, Chance MR, Jaussi R, et al.
Structural basis for the oligomerization-state switch from a dimer to a trimer of an engineered cortexillin-1 coiled-coil variant
PLoS One. 2013; 8(5): e63370 (7 pp.). https://doi.org/10.1371/journal.pone.0063370
DORA PSI
Brueckner F, Piscitelli CL, Tsai C-J, Standfuss J, Deupi X, Schertler GFX
Structure of β-Adrenergic receptors
In: Conn PM, ed. G protein coupled receptors. Structure. Methods in enzymology. San Diego: Elsevier; 2013:117-151. https://doi.org/10.1016/B978-0-12-391861-1.00006-X
DORA PSI
Bui KH, Ishikawa T
3D structural analysis of flagella/cilia by cryo-electron tomography
In: Marshall WF, ed. Cilia, part A. Methods in enzymology. Amsterdam: Elsevier; 2013:305-323. https://doi.org/10.1016/B978-0-12-397945-2.00017-2
DORA PSI
Duarte JM, Biyani N, Baskaran K, Capitani G
An analysis of oligomerization interfaces in transmembrane proteins
BMC Structural Biology. 2013; 13(1): 21 (11 pp.). https://doi.org/10.1186/1472-6807-13-21
DORA PSI
Džolić Z, Cametti M, Milić D, Žinić M
The formation of CuCl₂-specific metallogels of pyridyloxalamide derivatives in alcohols
Chemistry: A European Journal. 2013; 19(17): 5411-5416. https://doi.org/10.1002/chem.201204082
DORA PSI
Furger E, Frei DC, Schibli R, Fischer E, Prota AE
Structural basis for universal corrinoid recognition by the cobalamin transport protein haptocorrin
Journal of Biological Chemistry. 2013; 288(35): 25466-25476. https://doi.org/10.1074/jbc.M113.483271
DORA PSI
Gouridis G, Karamanou S, Sardis MF, Schärer MA, Capitani G, Economou A
Quaternary dynamics of the SecA motor drive translocase catalysis
Molecular Cell. 2013; 52(5): 655-666. https://doi.org/10.1016/j.molcel.2013.10.036
DORA PSI
Guichard P, Hachet V, Majubu N, Neves A, Demurtas D, Olieric N, et al.
Native architecture of the centriole proximal region reveals features underlying its 9-fold radial symmetry
Current Biology. 2013; 23(17): 1620-1628. https://doi.org/10.1016/j.cub.2013.06.061
DORA PSI
Hassaine G, Deluz C, Li X-D, Graff A, Vogel H, Nury H
Large scale expression and purification of the mouse 5-HT3 receptor
Biochimica et Biophysica Acta: Biomembranes. 2013; 1828(11): 2544-2552. https://doi.org/10.1016/j.bbamem.2013.05.028
DORA PSI
Hilbert M, Erat MC, Hachet V, Guichard P, Blank ID, Flückiger I, et al.
Caenorhabditis elegans centriolar protein SAS-6 forms a spiral that is consistent with imparting a ninefold symmetry
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2013; 110(28): 11373-11378. https://doi.org/10.1073/pnas.1302721110
DORA PSI
Holland JP, Kang A, Cohrs S, Selivanova SV, Milicevic Sephton S, Betzel T, et al.
Synthesis and evaluation of biphenyl compounds as kinesin spindle protein inhibitors
Chemistry and Biodiversity. 2013; 10(4): 538-555. https://doi.org/10.1002/cbdv.201200400
DORA PSI
Hutter I, Müller E, Kristiansen PM, Kresak S, Tiefenauer L
Polymer-based microfluidic device for measuring membrane protein activities
Microfluidics and Nanofluidics. 2013; 14(3-4): 421-429. https://doi.org/10.1007/s10404-012-1061-0
DORA PSI
Ishikawa T
3D structure of eukaryotic flagella/cilia by cryo-electron tomography
Biophysics. 2013; 9: 141-148. https://doi.org/10.2142/biophysics.9.141
DORA PSI
Leppänen V-M, Tvorogov D, Kisko K, Prota AE, Jeltsch M, Anisimov A, et al.
Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2013; 110(32): 12960-12965. https://doi.org/10.1073/pnas.1301415110
DORA PSI
Liebi M, Kuster S, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, et al.
Cholesterol-diethylenetriaminepentaacetate complexed with thulium ions integrated into bicelles to increase their magnetic alignability
Journal of Physical Chemistry B. 2013; 117(47): 14743-14748. https://doi.org/10.1021/jp406599c
DORA PSI
Lima E, Diaz A, Guizar-Sicairos M, Gorelick S, Pernot P, Schleier T, et al.
Cryo-scanning x-ray diffraction microscopy of frozen-hydrated yeast
Journal of Microscopy. 2013; 249(1): 1-7. https://doi.org/10.1111/j.1365-2818.2012.03682.x
DORA PSI
Maeda S, Schertler GFX
Production of GPCR and GPCR complexes for structure determination
Current Opinion in Structural Biology. 2013; 23(3): 381-392. https://doi.org/10.1016/j.sbi.2013.04.006
DORA PSI
Mohan R, Katrukha EA, Doodhi H, Smal I, Meijering E, Kapitein LC, et al.
End-binding proteins sensitize microtubules to the action of microtubule-targeting agents
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2013; 110(22): 8900-8905. https://doi.org/10.1073/pnas.1300395110
DORA PSI
Nakayama M, Berger P
Coordination of VEGF receptor trafficking and signaling by coreceptors
Experimental Cell Research. 2013; 319(9): 1340-1347. https://doi.org/10.1016/j.yexcr.2013.03.008
DORA PSI
Prota AE, Bargsten K, Zurwerra D, Field JJ, Díaz JF, Altmann K-H, et al.
Molecular mechanism of action of microtubule-stabilizing anticancer agents
Science. 2013; 339(6119): 587-590. https://doi.org/10.1126/science.1230582
DORA PSI
Prota AE, Magiera MM, Kuijpers M, Bargsten K, Frey D, Wieser M, et al.
Structural basis of tubulin tyrosination by tubulin tyrosine ligase
Journal of Cell Biology. 2013; 200(3): 259-270. https://doi.org/10.1083/jcb.201211017
DORA PSI
Rubini M, Schärer MA, Capitani G, Glockshuber R
(4R)- and (4S)-fluoroproline in the conserved cis-prolyl peptide bond of the thioredoxin fold: tertiary structure context dictates ring puckering
ChemBioChem. 2013; 14(9): 1053-1057. https://doi.org/10.1002/cbic.201300178
DORA PSI
Sen I, Veprintsev D, Akhmanova A, Steinmetz MO
End binding proteins are obligatory dimers
PLoS One. 2013; 8(9): e74448 (7 pp.). https://doi.org/10.1371/journal.pone.0074448
DORA PSI
Singhal A, Ostermaier MK, Vishnivetskiy SA, Panneels V, Homan KT, Tesmer JJG, et al.
Insights into congenital stationary night blindness based on the structure of G90D rhodopsin
EMBO Reports. 2013; 14(6): 520-526. https://doi.org/10.1038/embor.2013.44
DORA PSI
Sun D, Ostermaier MK, Heydenreich FM, Mayer D, Jaussi R, Standfuss J, et al.
AAscan, PCRdesign and MutantChecker: a suite of programs for primer design and sequence analysis for high-throughput scanning mutagenesis.
PLoS One. 2013; 8(10): e78878 (9 pp.). https://doi.org/10.1371/journal.pone.0078878
DORA PSI
Suomalainen M, Luisoni S, Boucke K, Bianchi S, Engel DA, Greber UF
A direct and versatile assay measuring membrane penetration of adenovirus in single cells
Journal of Virology. 2013; 87(22): 12367-12379. https://doi.org/10.1128/JVI.01833-13
DORA PSI
Tsai C-J, Tani K, Irie K, Hiroaki Y, Shimomura T, McMillan DG, et al.
Two alternative conformations of a voltage-gated sodium channel
Journal of Molecular Biology. 2013; 425(22): 4074-4088. https://doi.org/10.1016/j.jmb.2013.06.036
DORA PSI
Vishnivetskiy SA, Ostermaier MK, Singhal A, Panneels V, Homan KT, Glukhova A, et al.
Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding
Cellular Signalling. 2013; 25(11): 2155-2162. https://doi.org/10.1016/j.cellsig.2013.07.009
DORA PSI

Abela E, Missimer J, Wiest R, Federspiel A, Hess C, Sturzenegger M, et al.
Lesions to primary sensory and posterior parietal cortices impair recovery from hand paresis after stroke
PLoS One. 2012; 7(2): e31275 (12 pp.). https://doi.org/10.1371/journal.pone.0031275
DORA PSI
Alfieri A, Watson JJ, Kammerer RA, Tasab M, Progias P, Reeves K, et al.
Angiopoietin-1 variant reduces LPS-induced microvascular dysfunction in a murine model of sepsis
Critical Care. 2012; 16(5): R182 (12 pp.). https://doi.org/10.1186/cc11666
DORA PSI
Allison JR, Hertig S, Missimer JH, Smith LJ, Steinmetz MO, Dolenc J
Probing the structure and dynamics of proteins by combining molecular dynamics simulations and experimental NMR data
Journal of Chemical Theory and Computation. 2012; 8(10): 3430-3444. https://doi.org/10.1021/ct300393b
DORA PSI
Alves-Silva J, Sánchez-Soriano N, Beaven R, Klein M, Parkin J, Millard TH, et al.
Spectraplakins promote microtubule-mediated axonal growth by functioning as structural microtubule-associated proteins and EB1-dependent +TIPs (tip interacting proteins)
Journal of Neuroscience. 2012; 32(27): 9143-9158. https://doi.org/10.1523/JNEUROSCI.0416-12.2012
DORA PSI
Bjelić S, De Groot CO, Schärer MA, Jaussi R, Bargsten K, Salzmann M, et al.
Interaction of mammalian end binding proteins with CAP-Gly domains of CLIP-170 and p150^glued
Journal of Structural Biology. 2012; 177(1): 160-167. https://doi.org/10.1016/j.jsb.2011.11.010
DORA PSI
Brandt T, Townsley FM, Teufel DP, Freund SMV, Veprintsev DB
Molecular basis for modulation of the p53 target selectivity by KLF4
PLoS One. 2012; 7(10): e48252 (11 pp.). https://doi.org/10.1371/journal.pone.0048252
DORA PSI
Brandt T, Kaar JL, Fersht AR, Veprintsev DB
Stability of p53 Homologs
PLoS One. 2012; 7(10): e47889 (8 pp.). https://doi.org/10.1371/journal.pone.0047889
DORA PSI
Brozzo MS, Bjelić S, Kisko K, Schleier T, Leppänen V-M, Alitalo K, et al.
Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization
Blood. 2012; 119(7): 1781-1788. https://doi.org/10.1182/blood-2011-11-390922
DORA PSI
Buey RM, Sen I, Kortt O, Mohan R, Gfeller D, Veprintsev D, et al.
Sequence determinants of a microtubule tip localization signal (MtLS)
Journal of Biological Chemistry. 2012; 287(34): 28227-28242. https://doi.org/10.1074/jbc.M112.373928
DORA PSI
Bui KH, Yagi T, Yamamoto R, Kamiya R, Ishikawa T
Polarity and asymmetry in the arrangement of dynein and related structures in the Chlamydomonas axoneme
Journal of Cell Biology. 2012; 198(5): 913-925. https://doi.org/10.1083/jcb.201201120
DORA PSI
Calligaris D, Manatschal C, Marcellin M, Villard C, Monsarrat B, Burlet-Schiltz O, et al.
Tyrosine-dependent capture of CAP-Gly domain-containing proteins in complex mixture by EB1 C-terminal peptidic probes
Journal of Proteomics. 2012; 75(12): 3605-3616. https://doi.org/10.1016/j.jprot.2012.04.006
DORA PSI
Crespo MD, Puorger C, Schärer MA, Eidam O, Grütter MG, Capitani G, et al.
Quality control of disulfide bond formation in pilus subunits by the chaperone FimC
Nature Chemical Biology. 2012; 8(8): 707-713. https://doi.org/10.1038/nchembio.1019
DORA PSI
Deupi X, Standfuss J, Schertler G
Conserved activation pathways in G-protein-coupled receptors
Biochemical Society Transactions. 2012; 40(2): 383-388. https://doi.org/10.1042/BST20120001
DORA PSI
Deupi X, Li X-D, Schertler GFX
Ligands stabilize specific GPCR conformations: but how?
Structure. 2012; 20(8): 1289-1290. https://doi.org/10.1016/j.str.2012.07.009
DORA PSI
Deupi X, Edwards P, Singhal A, Nickle B, Oprian D, Schertler G, et al.
Stabilized G protein binding site in the structure of constitutively active metarhodopsin-II
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2012; 109(1): 119-124. https://doi.org/10.1073/pnas.1114089108
DORA PSI
Dinkel H, Michael S, Weatheritt RJ, Davey NE, Van Roey K, Altenberg B, et al.
ELM - the database of eukaryotic linear motifs
Nucleic Acids Research. 2012; 40(D1): D242-D251. https://doi.org/10.1093/nar/gkr1064
DORA PSI
Duarte JM, Srebniak A, Schärer MA, Capitani G
Protein interface classification by evolutionary analysis
BMC Bioinformatics. 2012; 13(1): 334 (16 pp.). https://doi.org/10.1186/1471-2105-13-334
DORA PSI
Gabizon R, Brandt T, Sukenik S, Lahav N, Lebendiker M, Shalev DE, et al.
Specific recognition of p53 tetramers by peptides derived from p53 interacting proteins
PLoS One. 2012; 7(5): e38060 (11 pp.). https://doi.org/10.1371/journal.pone.0038060
DORA PSI
Hyde CAC, Giese A, Stuttfeld E, Saliba JA, Villemagne D, Schleier T, et al.
Targeting extracellular domains D4 and D7 of vascular endothelial growth factor receptor 2 reveals allosteric receptor regulatory sites
Molecular and Cellular Biology. 2012; 32(19): 3802-3813. https://doi.org/10.1128/MCB.06787-11
DORA PSI
Ishikawa T
Structural biology of cytoplasmic and axonemal dyneins
Journal of Structural Biology. 2012; 179(2): 229-234. https://doi.org/10.1016/j.jsb.2012.05.016
DORA PSI
Jiang K, Toedt G, Montenegro Gouveia S, Davey NE, Hua S, van der Vaart B, et al.
A proteome-wide screen for mammalian SxIP motif-containing microtubule plus-end tracking proteins
Current Biology. 2012; 22(19): 1800-1807. https://doi.org/10.1016/j.cub.2012.07.047
DORA PSI
Junker K, Zandomeneghi G, Guo Z, Kissner R, Ishikawa T, Kohlbrecher J, et al.
Mechanistic aspects of the horseradish peroxidase-catalysed polymerisation of aniline in the presence of AOT vesicles as templates
RSC Advances. 2012; 2(16): 6478-6495. https://doi.org/10.1039/c2ra20566a
DORA PSI
Liebi M, Kohlbrecher J, Ishikawa T, Fischer P, Walde P, Windhab EJ
Cholesterol increases the magnetic aligning of bicellar disks from an aqueous mixture of DMPC and DMPE-DTPA with complexed thulium ions
Langmuir. 2012; 28(29): 10905-10915. https://doi.org/10.1021/la3019327
DORA PSI
Lopus M, Manatschal C, Buey RM, Bjelić S, Miller HP, Steinmetz MO, et al.
Cooperative stabilization of microtubule dynamics by EB1 and CLIP-170 involves displacement of stably bound P_i at microtubule ends
Biochemistry. 2012; 51(14): 3021-3030. https://doi.org/10.1021/bi300038t
DORA PSI
Lowell AN, Qiao H, Liu T, Ishikawa T, Zhang H, Oriana S, et al.
Functionalized low-density lipoprotein nanoparticles for in vivo enhancement of atherosclerosis on magnetic resonance images
Bioconjugate Chemistry. 2012; 23(11): 2313-2319. https://doi.org/10.1021/bc300561e
DORA PSI
Maheshwari A, Ishikawa T
Heterogeneity of dynein structure implies coordinated suppression of dynein motor activity in the axoneme
Journal of Structural Biology. 2012; 179(2): 235-241. https://doi.org/10.1016/j.jsb.2012.04.018
DORA PSI
Marković M, Milić D, Sabolović J
Modeling triple conformational disorder in a new crystal polymorph of cis-aquabis(L-isoleucinato)copper(II)
Crystal Growth and Design. 2012; 12(8): 4116-4129. https://doi.org/10.1021/cg300636w
DORA PSI
Missimer JH, Steinmetz MO, van Gunsteren WF, Dolenc J
Influence of 63Ser phosphorylation and dephosphorylation on the structure of the stathmin helical nucleation sequence: a molecular dynamics study
Biochemistry. 2012; 51(42): 8455-8463. https://doi.org/10.1021/bi300885y
DORA PSI
Pham SQ, Pompidor G, Liu J, Li X-D, Li Z
Evolving P450pyr hydroxylase for highly enantioselective hydroxylation at non-activated carbon atom
Chemical Communications. 2012; 48(38): 4618-4620. https://doi.org/10.1039/c2cc30779k
DORA PSI
Pigino G, Maheshwari A, Bui KH, Shingyoji C, Kamimura S, Ishikawa T
Comparative structural analysis of eukaryotic flagella and cilia from Chlamydomonas, Tetrahymena, and sea urchins
Journal of Structural Biology. 2012; 178(2): 199-206. https://doi.org/10.1016/j.jsb.2012.02.012
DORA PSI
Roberts AJ, Malkova B, Walker ML, Sakakibara H, Numata N, Kon T, et al.
ATP-driven remodeling of the linker domain in the dynein motor
Structure. 2012; 20(10): 1670-1680. https://doi.org/10.1016/j.str.2012.07.003
DORA PSI
Tiefenauer L, Demarche S
Challenges in the development of functional assays of membrane proteins
Materials. 2012; 5(11): 2205-2242. https://doi.org/10.3390/ma5112205
DORA PSI
Tokutsu R, Kato N, Bui KH, Ishikawa T, Minagawa J
Revisiting the supramolecular organization of photosystem II in Chlamydomonas reinhardtii
Journal of Biological Chemistry. 2012; 287(37): 31574-31581. https://doi.org/10.1074/jbc.M111.331991
DORA PSI
Ueno H, Ishikawa T, Bui KH, Gonda K, Ishikawa T, Yamaguchi T
Analysis of ciliary motion and the axonemal structure in the mouse respiratory cilia
In: ASME 2012 summer bioengineering conference, SBC 2012. ; 2012:(2 pp.). https://doi.org/10.1115/SBC2012-80232
DORA PSI
Ueno H, Ishikawa T, Bui KH, Gonda K, Ishikawa T, Yamaguchi T
Mouse respiratory cilia with the asymmetric axonemal structure on sparsely distributed ciliary cells can generate overall directional flow
Nanomedicine: Nanotechnology, Biology and Medicine. 2012; 8(7): 1081-1087. https://doi.org/10.1016/j.nano.2012.01.004
DORA PSI
Vogel SM, Bauer MR, Joerger AC, Wilcken R, Brandt T, Veprintsev DB, et al.
Lithocholic acid is an endogenous inhibitor of MDM4 and MDM2
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2012; 109(42): 16906-16910. https://doi.org/10.1073/pnas.1215060109
DORA PSI
de la Roche M, Rutherford TJ, Gupta D, Veprintsev DB, Saxty B, Freund SM, et al.
An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid
Nature Communications. 2012; 3: 680 (10 pp.). https://doi.org/10.1038/ncomms1680
DORA PSI

Akhmanova A, Steinmetz MO
Microtubule end binding: EBs sense the guanine nucleotide state
Current Biology. 2011; 21(8): R283-R285. https://doi.org/10.1016/j.cub.2011.03.023
DORA PSI
Arbely E, Natan E, Brandt T, Allen MD, Veprintsev DB, Robinson CV, et al.
Acetylation of lysine 120 of p53 endows DNA-binding specificity at effective physiological salt concentration
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2011; 108(20): 8251-8256. https://doi.org/10.1073/pnas.1105028108
DORA PSI
Ballmer-Hofer K, Andersson AE, Ratcliffe LE, Berger P
Neuropilin-1 promotes VEGFR-2 trafficking through Rab11 vesicles thereby specifying signal output
Blood. 2011; 118(3): 816-826. https://doi.org/10.1182/blood-2011-01-328773
DORA PSI
Balsera M, Buey RM, Li X-D
Quaternary structure of the oxaloacetate decarboxylase membrane complex and mechanistic relationships to pyruvate carboxylases
Journal of Biological Chemistry. 2011; 286(11): 9457-9467. https://doi.org/10.1074/jbc.M110.197442
DORA PSI
Beecher N, Roseman AM, Jowitt TA, Berry R, Troilo H, Kammerer RA, et al.
Collagen VI, conformation of A-domain arrays and microfibril architecture
Journal of Biological Chemistry. 2011; 286(46): 40266-40275. https://doi.org/10.1074/jbc.M111.265595
DORA PSI
Berger P, Kriz A, Schmid K, Ballmer K
Integration of multiple expression cassettes into mammalian genomes in a single step
London: Springer Nature; 2011. Protocol exchange. https://doi.org/10.1038/protex.2011.249
DORA PSI
Berger P, Tersar K, Ballmer-Hofer K, Suter U
The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling
Journal of Cellular and Molecular Medicine. 2011; 15(2): 307-315. https://doi.org/10.1111/j.1582-4934.2009.00967.x
DORA PSI
Berger P, Ballmer-Hofer K
The reception and the party after: how vascular endothelial growth factor receptor 2 explores cytoplasmic space
Swiss Medical Weekly. 2011; 141: w13318 (8 pp.). https://doi.org/10.4414/smw.2011.13318
DORA PSI
Bourquin F, Capitani G, Grütter MG
PLP-dependent enzymes as entry and exit gates of sphingolipid metabolism
Protein Science. 2011; 20(9): 1492-1508. https://doi.org/10.1002/pro.679
DORA PSI
Buey RM, Mohan R, Leslie K, Walzthoeni T, Missimer JH, Menzel A, et al.
Insights into EB1 structure and the role of its c-terminal domain for discriminating microtubule tips from the lattice
Molecular Biology of the Cell. 2011; 22(16): 2912-2923. https://doi.org/10.1091/mbc.E11-01-0017
DORA PSI
Bui KH, Pigino G, Ishikawa T
Three-dimensional structural analysis of eukaryotic flagella/cilia by electron cryo-tomography
Journal of Synchrotron Radiation. 2011; 18(1): 2-5. https://doi.org/10.1107/S0909049510036812
DORA PSI
Demarche S, Sugihara K, Zambelli T, Tiefenauer L, Vörös J
Techniques for recording reconstituted ion channels
Analyst. 2011; 136(6): 1077-1089. https://doi.org/10.1039/c0an00828a
DORA PSI
Deupi X, Standfuss J
Structural insights into agonist-induced activation of G-protein-coupled receptors
Current Opinion in Structural Biology. 2011; 21(4): 541-551. https://doi.org/10.1016/j.sbi.2011.06.002
DORA PSI
Eustermann S, Videler H, Yang J-C, Cole PT, Gruszka D, Veprintsev D, et al.
The DNA-binding domain of human PARP-1 interacts with DNA single-strand breaks as a monomer through its second zinc finger
Journal of Molecular Biology. 2011; 407(1): 149-170. https://doi.org/10.1016/j.jmb.2011.01.034
DORA PSI
Glubb DM, Cerri E, Giese A, Zhang W, Mirza O, Thompson EE, et al.
Novel functional germline variants in the VEGF receptor 2 gene and their effect on gene expression and microvessel density in lung cancer
Clinical Cancer Research. 2011; 17(16): 5257-5267. https://doi.org/10.1158/1078-0432.CCR-11-0379
DORA PSI
Huwiler A, Bourquin F, Kotelevets N, Pastukhov O, Capitani G, Grütter MG, et al.
A prokaryotic S1P lyase degrades extracellular S1P in vitro and in vivo: Implication for treating hyperproliferative disorders
PLoS One. 2011; 6(8): e22436 (11 pp.). https://doi.org/10.1371/journal.pone.0022436
DORA PSI
Ishikawa T
3D structures of axonemes
In: Hirose K, ed. Handbook of Dynein. New York: Jenny Stanford Publishing; 2011:245-266. https://doi.org/10.1201/b11622
DORA PSI
Ishikawa T
Organization of dyneins in the axoneme
In: King SM, ed. Dyneins. Structure, biology and disease. Elsevier; 2011:244-271. https://doi.org/10.1016/B978-0-12-382004-4.10008-1
DORA PSI
Kisko K, Brozzo MS, Missimer J, Schleier T, Menzel A, Leppänen V-M, et al.
Structural analysis of vascular endothelial growth factor receptor-2/ligand complexes by small-angle X-ray solution scattering
FASEB Journal. 2011; 25(9): 2980-2986. https://doi.org/10.1096/fj.11-185397
DORA PSI
Kitagawa D, Vakonakis I, Olieric N, Hilbert M, Keller D, Olieric V, et al.
Structural basis of the 9-fold symmetry of centrioles
Cell. 2011; 144(3): 364 (12 pp.)-375. https://doi.org/10.1016/j.cell.2011.01.008
DORA PSI
Leppänen V-M, Jeltsch M, Anisimov A, Tvorogov D, Aho K, Kalkkinen N, et al.
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity
Blood. 2011; 117(5): 1507-1515. https://doi.org/10.1182/blood-2010-08-301549
DORA PSI
Maeda S, Tsukihara T
Structure of the gap junction channel and its implications for its biological functions
Cellular and Molecular Life Sciences. 2011; 68(7): 1115-1129. https://doi.org/10.1007/s00018-010-0551-z
DORA PSI
Maeda S
ヒト由来ギャップ結合チャネルの構造解析. Structure analysis of human gap junction channel
Seikagaku. 2011; 83(1): 36-40.
DORA PSI
Melero R, Rajagopalan S, Lázaro M, Joerger AC, Brandt T, Veprintsev DB, et al.
Electron microscopy studies on the quaternary structure of p53 reveal different binding modes for p53 tetramers in complex with DNA
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2011; 108(2): 557-562. https://doi.org/10.1073/pnas.1015520107
DORA PSI
Nakagawa S, Gong X-Q, Maeda S, Dong Y, Misumi Y, Tsukihara T, et al.
Asparagine 175 of connexin32 is a critical residue for docking and forming functional heterotypic gap junction channels with connexin26
Journal of Biological Chemistry. 2011; 286(22): 19672-19681. https://doi.org/10.1074/jbc.M110.204958
DORA PSI
Pigino G, Bui KH, Maheshwari A, Lupetti P, Diener D, Ishikawa T
Cryoelectron tomography of radial spokes in cilia and flagella
Journal of Cell Biology. 2011; 195(4): 673-687. https://doi.org/10.1083/jcb.201106125
DORA PSI
Rajendran C, Gerhardt ECM, Bjelic S, Gasperina A, Scarduelli M, Pedrosa FO, et al.
Crystal structure of the GlnZ-DraG complex reveals a different form of P_II-target interaction
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2011; 108(47): 18972-18976. https://doi.org/10.1073/pnas.1108038108
DORA PSI
Rossmann M, Sukumaran M, Penn AC, Veprintsev DB, Babu MM, Greger IH
Subunit-selective N-terminal domain associations organize the formation of AMPA receptor heteromers
EMBO Journal. 2011; 30(5): 959-971. https://doi.org/10.1038/emboj.2011.16
DORA PSI
Schärer MA, Eliot AC, Grütter MG, Capitani G
Structural basis for reduced activity of 1-aminocyclopropane-1-carboxylate synthase affected by a mutation linked to andromonoecy
FEBS Letters. 2011; 585(1): 111-114. https://doi.org/10.1016/j.febslet.2010.11.013
DORA PSI
Standfuss J, Edwards PC, D'Antona A, Fransen M, Xie G, Oprian DD, et al.
The structural basis of agonist-induced activation in constitutively active rhodopsin
Nature. 2011; 471(7340): 656-660. https://doi.org/10.1038/nature09795
DORA PSI
Stehr H, Jang S-HJ, Duarte JM, Wierling C, Lehrach H, Lappe M, et al.
The structural impact of cancer-associated missense mutations in oncogenes and tumor suppressors
Molecular Cancer. 2011; 10: 54 (10 pp.). https://doi.org/10.1186/1476-4598-10-54
DORA PSI
Stroud MJ, Kammerer RA, Ballestrem C
Characterization of G2L3 (GAS2-like 3), a new microtubule- and actin-binding protein related to spectraplakins
Journal of Biological Chemistry. 2011; 286(28): 24987-24995. https://doi.org/10.1074/jbc.M111.242263
DORA PSI
Studer A, Demarche S, Langenegger D, Tiefenauer L
Integration and recording of a reconstituted voltage-gated sodium channel in planar lipid bilayers
Biosensors and Bioelectronics. 2011; 26(5): 1924-1928. https://doi.org/10.1016/j.bios.2010.06.008
DORA PSI
Vehlow C, Stehr H, Winkelmann M, Duarte JM, Petzold L, Dinse J, et al.
CMView: interactive contact map visualization and analysis
Bioinformatics. 2011; 27(11): 1573-1574. https://doi.org/10.1093/bioinformatics/btr163
DORA PSI
Xie G, D'Antona AM, Edwards PC, Fransen M, Standfuss J, Schertler GFX, et al.
Preparation of an activated rhodopsin/transducin complex using a constitutively active mutant of rhodopsin
Biochemistry. 2011; 50(47): 10399-10407. https://doi.org/10.1021/bi201126r
DORA PSI
van Breugel M, Hirono M, Andreeva A, Yanagisawa H-A, Yamaguchi S, Nakazawa Y, et al.
Structures of SAS-6 suggest its organization in centrioles
Science. 2011; 331(6021): 1196-1199. https://doi.org/10.1126/science.1199325
DORA PSI
van der Vaart B, Manatschal C, Grigoriev I, Olieric V, Gouveia SM, Bjelić S, et al.
SLAIN2 links microtubule plus end-tracking proteins and controls microtubule growth in interphase
Journal of Cell Biology. 2011; 193(6): 1083-1099. https://doi.org/10.1083/jcb.201012179
DORA PSI

Tsai CJ, Ziegler C
Coupling electron cryomicroscopy and X-ray crystallography to understand secondary active transport
Current Opinion in Structural Biology. 2010; 20(4): 448-455. https://doi.org/10.1016/j.sbi.2010.06.005
DORA PSI

Akhmanova A, Steinmetz MO
Microtubule +TIPs at a glance
Journal of Cell Science. 2010; 123(20): 3415-3419. https://doi.org/10.1242/jcs.062414
DORA PSI
Bourquin F, Riezman H, Capitani G, Grütter MG
Structure and function of sphingosine-1-phosphate lyase, a key enzyme of sphingolipid metabolism
Structure. 2010; 18(8): 1054-1065. https://doi.org/10.1016/j.str.2010.05.011
DORA PSI
Ciani B, Bjelić S, Honnappa S, Jawhari H, Jaussi R, Payapilly A, et al.
Molecular basis of coiled-coil oligomerization-state specificity
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2010; 107(46): 19850-19855. https://doi.org/10.1073/pnas.1008502107
DORA PSI
De Groot CO, Jelesarov I, Damberger FF, Bjelić S, Schärer MA, Bhavesh NS, et al.
Molecular insights into mammalian end-binding protein heterodimerization
Journal of Biological Chemistry. 2010; 285(8): 5802-5814. https://doi.org/10.1074/jbc.M109.068130
DORA PSI
Dell'Era Dosch D, Ballmer-Hofer K
Transmembrane domain-mediated orientation of receptor monomers in active VEGFR-2 dimers
FASEB Journal. 2010; 24(1): 32-38. https://doi.org/10.1096/fj.09-132670
DORA PSI
Dolenc J, Missimer JH, Steinmetz MO, van Gunsteren WF
Methods of NMR structure refinement: molecular dynamics simulations improve the agreement with measured NMR data of a C-terminal peptide of GCN4-p1
Journal of Biomolecular NMR. 2010; 47(3): 221-235. https://doi.org/10.1007/s10858-010-9425-9
DORA PSI
Duarte JM, Sathyapriya R, Stehr H, Filippis I, Lappe M
Optimal contact definition for reconstruction of contact maps
BMC Bioinformatics. 2010; 11: 283 (10 pp.). https://doi.org/10.1186/1471-2105-11-283
DORA PSI
Figueira ACM, Polikarpov I, Veprintsev D, Santos GM
Dissecting the relation between a nuclear receptor and GATA: binding affinity studies of thyroid hormone receptor and GATA2 on TSHβ promoter
PLoS One. 2010; 5(9): e12628 (10 pp.). https://doi.org/10.1371/journal.pone.0012628
DORA PSI
Galão RP, Chari A, Alves-Rodrigues I, Lobão D, Mas A, Kambach C, et al.
LSm1-7 complexes bind to specific sites in viral RNA genomes and regulate their translation and replication
RNA. 2010; 16(4): 817-827. https://doi.org/10.1261/rna.1712910
DORA PSI
Grünewald FS, Prota AE, Giese A, Ballmer-Hofer K
Structure-function analysis of VEGF receptor activation and the role of coreceptors in angiogenic signaling
Biochimica et Biophysica Acta: Proteins and Proteomics. 2010; 1804(3): 567-580. https://doi.org/10.1016/j.bbapap.2009.09.002
DORA PSI
Kriz A, Schmid K, Baumgartner N, Ziegler U, Berger I, Ballmer-Hofer K, et al.
A plasmid-based multigene expression system for mammalian cells
Nature Communications. 2010; 1(8): 120 (6 pp.). https://doi.org/10.1038/ncomms1120
DORA PSI
Lachkar S, Lebois M, Steinmetz MO, Guichet A, Lal N, Curmi PA, et al.
Drosophila stathmins bind tubulin heterodimers with high and variable stoichiometries
Journal of Biological Chemistry. 2010; 285(15): 11667-11680. https://doi.org/10.1074/jbc.M109.096727
DORA PSI
Leppänen V-M, Prota AE, Jeltsch M, Anisimov A, Kalkkinen N, Strandin T, et al.
Structural determinants of growth factor binding and specificity by VEGF receptor 2
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2010; 107(6): 2425-2430. https://doi.org/10.1073/pnas.0914318107
DORA PSI
Macdonald PR, Lustig A, Steinmetz MO, Kammerer RA
Laminin chain assembly is regulated by specific coiled-coil interactions
Journal of Structural Biology. 2010; 170(2): 398-405. https://doi.org/10.1016/j.jsb.2010.02.004
DORA PSI
Missimer JH, Seitz RJ, Kleiser R
Data-driven analyses of an fMRI study of a subject experiencing phosphenes
Journal of Magnetic Resonance Imaging. 2010; 31(4): 821-828. https://doi.org/10.1002/jmri.22122
DORA PSI
Missimer JH, Dolenc J, Steinmetz MO, Van Gunsteren WF
Exploring the trigger sequence of the GCN4 coiled-coil: biased molecular dynamics resolves apparent inconsistencies in NMR measurements
Protein Science. 2010; 19(12): 2462-2474. https://doi.org/10.1002/pro.528
DORA PSI
Mitola S, Ravelli C, Moroni E, Salvi V, Leali D, Ballmer-Hofer K, et al.
Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2
Blood. 2010; 116(18): 3677-3680. https://doi.org/10.1182/blood-2010-06-291930
DORA PSI
Montenegro Gouveia S, Leslie K, Kapitein LC, Buey RM, Grigoriev I, Wagenbach M, et al.
In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends
Current Biology. 2010; 20(19): 1717-1722. https://doi.org/10.1016/j.cub.2010.08.020
DORA PSI
Olieric N, Kuchen M, Wagen S, Sauter M, Crone S, Edmondson S, et al.
Automated seamless DNA co-transformation cloning with direct expression vectors applying positive or negative insert selection
BMC Biotechnology. 2010; 10: 56 (10 pp.). https://doi.org/10.1186/1472-6750-10-56
DORA PSI
Rinderknecht M, Villa A, Ballmer-Hofer K, Neri D, Detmar M
Phage-derived fully human monoclonal antibody fragments to human vascular endothelial growth factor-C block its interaction with VEGF receptor-2 and 3
PLoS One. 2010; 5(8): e11941 (16 pp.). https://doi.org/10.1371/journal.pone.0011941
DORA PSI
Schmidt F, Treiber N, Zocher G, Bjelic S, Steinmetz MO, Kalbacher H, et al.
Insights into peroxisome function from the structure of PEX3 in complex with a soluble fragment of PEX19
Journal of Biological Chemistry. 2010; 285(33): 25410-25417. https://doi.org/10.1074/jbc.M110.138503
DORA PSI
Schärer MA, Grütter MG, Capitani G
CRK: an evolutionary approach for distinguishing biologically relevant interfaces from crystal contacts
Proteins. 2010; 78(12): 2707-2713. https://doi.org/10.1002/prot.22787
DORA PSI
Stehr H, Duarte JM, Lappe M, Bhak J, Bolser DM
PDBWiki: added value through community annotation of the Protein Data Bank
Database: The Journal of Biological Databases and Curation. 2010; 2010: baq009 (8 pp.). https://doi.org/10.1093/database/baq009
DORA PSI
Truan D, Huergo LF, Chubatsu LS, Merrick M, Li X-D, Winkler FK
A new P_II protein structure identifies the 2-oxoglutarate binding site
Journal of Molecular Biology. 2010; 400(3): 531-539. https://doi.org/10.1016/j.jmb.2010.05.036
DORA PSI

Balsera M, Goetze TA, Kovács-Bogdán E, Schürmann P, Wagner R, Buchanan BB, et al.
Characterization of Tic110, a channel-forming protein at the inner envelope membrane of chloroplasts, unveils a response to Ca²⁺ and a stromal regulatory disulfide bridge
Journal of Biological Chemistry. 2009; 284(5): 2603-2616. https://doi.org/10.1074/jbc.M807134200
DORA PSI
Balsera M, Soll J, Buchanan BB
Protein import in chloroplasts: an emerging regulatory role for redox
In: Jacquot J-P, ed. Oxidative stress an redox regulation in plants. Advances in botanical research. Amsterdam: Elsevier; 2009:277-332. https://doi.org/10.1016/S0065-2296(10)52010-X
DORA PSI
Balsera M, Soll J, Bölter B
Protein import machineries in endosymbiotic organelles
Cellular and Molecular Life Sciences. 2009; 66(11-12): 1903-1923. https://doi.org/10.1007/s00018-009-8644-2
DORA PSI
Bieniossek C, Nie Y, Frey D, Olieric N, Schaffitzel C, Collinson I, et al.
Automated unrestricted multigene recombineering for multiprotein complex production
Nature Methods. 2009; 6(6): 447-450. https://doi.org/10.1038/nmeth.1326
DORA PSI
Friedli A, Fischer E, Novak-Hofer I, Cohrs S, Ballmer-Hofer K, Schubiger PA, et al.
The soluble form of the cancer-associated L1 cell adhesion molecule is a pro-angiogenic factor
International Journal of Biochemistry and Cell Biology. 2009; 41(7): 1572-1580. https://doi.org/10.1016/j.biocel.2009.01.006
DORA PSI
Gut H, Dominici P, Pilati S, Astegno A, Petoukhov MV, Svergun DI, et al.
A common structural basis for pH- and calmodulin-mediated regulation in plant glutamate decarboxylase
Journal of Molecular Biology. 2009; 392(2): 334-351. https://doi.org/10.1016/j.jmb.2009.06.080
DORA PSI
Honnappa S, Gouveia SM, Weisbrich A, Damberger FF, Bhavesh NS, Jawhari H, et al.
An EB1-binding motif acts as a microtubule tip localization signal
Cell. 2009; 138(2): 366-376. https://doi.org/10.1016/j.cell.2009.04.065
DORA PSI
Komarova Y, De Groot CO, Grigoriev I, Gouveia SM, Munteanu EL, Schober JM, et al.
Mammalian end binding proteins control persistent microtubule growth
Journal of Cell Biology. 2009; 184(5): 691-706. https://doi.org/10.1083/jcb.200807179
DORA PSI
Li X-D, Huergo LF, Gasperina A, Pedrosa FO, Merrick M, Winkler FK
Crystal Structure of Dinitrogenase Reductase-activating Glycohydrolase (DRAG) Reveals Conservation in the ADP-Ribosylhydrolase Fold and Specific Features in the ADP-Ribose-binding Pocket
Journal of Molecular Biology. 2009; 390(4): 737-746. https://doi.org/10.1016/j.jmb.2009.05.031
DORA PSI
Lingaraju GM, Prota AE, Winkler FK
Mutational studies of Pa-AGOG DNA glycosylase from the hyperthermophilic crenarchaeon Pyrobaculum aerophilum
DNA Repair. 2009; 8(7): 857-864. https://doi.org/10.1016/j.dnarep.2009.03.009
DORA PSI
Manna T, Thrower DA, Honnappa S, Steinmetz MO, Wilson L
Regulation of microtubule dynamic instability in vitro by differentially phosphorylated stathmin
Journal of Biological Chemistry. 2009; 284(23): 15640-15649. https://doi.org/10.1074/jbc.M900343200
DORA PSI
Palfi Z, Jaé N, Preußer C, Kaminska KH, Bujnicki JM, Lee JH, et al.
SMN-assisted assembly of snRNP-specific Sm cores in trypanosomes
Genes and Development. 2009; 23(14): 1650-1664. https://doi.org/10.1101/gad.526109
DORA PSI
Pennacchietti E, Lammens TM, Capitani G, Franssen MCR, John RA, Bossa F, et al.
Mutation of His⁴⁶⁵ alters the pH-dependent spectroscopic properties of Escherichia coli glutamate decarboxylase and broadens the range of its activity toward more alkaline pH
Journal of Biological Chemistry. 2009; 284(46): 31587-31596. https://doi.org/10.1074/jbc.M109.049577
DORA PSI
Studer A, Han X, Winkler FK, Tiefenauer LX
Formation of individual protein channels in lipid bilayers suspended in nanopores
Colloids and Surfaces B: Biointerfaces. 2009; 73(2): 325-331. https://doi.org/10.1016/j.colsurfb.2009.06.006
DORA PSI
Stuttfeld E, Ballmer-Hofer K
Structure and function of VEGF receptors
IUBMB Life. 2009; 61(9): 915-922. https://doi.org/10.1002/iub.234
DORA PSI
Tremmel M, Matzke A, Albrecht I, Laib AM, Olaku V, Ballmer-Hofer K, et al.
A CD44v6 peptide reveals a role of CD44 in VEGFR-2 signaling and angiogenesis
Blood. 2009; 114(25): 5236-5244. https://doi.org/10.1182/blood-2009-04-219204
DORA PSI
Wasmer C, Benkemoun L, Sabaté R, Steinmetz MO, Coulary-Salin B, Wang L, et al.
Solid-state NMR spectroscopy reveals that E. coli inclusion bodies of HET-s(218-289) are amyloids
Angewandte Chemie International Edition. 2009; 48(26): 4858-4860. https://doi.org/10.1002/anie.200806100
DORA PSI
Patterson BD, Heyderman L, Milne C, Thibault P, Ballmer K, Staub U, eds.
Ultrafast phenomena at the nanoscale: science opportunities at the SwissFEL X-ray laser
Villigen PSI, Switzerland: Paul Scherrer Institut; 2009.
DORA PSI
Akhmanova A, Steinmetz MO
Tracking the ends: a dynamic protein network controls the fate of microtubule tips
Nature Reviews Molecular Cell Biology. 2008; 9(4): 309-322. https://doi.org/10.1038/nrm2369
DORA PSI
Azzaroni O, Mir M, Álvarez M, Tiefenauer L, Knoll W
Electrochemical rectification by redox-labeled bioconjugates: molecular building blocks for the construction of biodiodes
Langmuir. 2008; 24(6): 2878-2883. https://doi.org/10.1021/la703536a
DORA PSI
Cébe-Suarez S, Grünewald FS, Jaussi R, Li X, Claesson-Welsh L, Spillmann D, et al.
Orf virus VEGF-E NZ2 promotes paracellular NRP-1/VEGFR-2 coreceptor assembly via the peptide RPPR
FASEB Journal. 2008; 22(8): 3078-3086. https://doi.org/10.1096/fj.08-107219
DORA PSI
Dais C, Solak HH, Müller E, Grützmacher D
Impact of template variations on shape and arrangement of Si/Ge quantum dot arrays
Applied Physics Letters. 2008; 92(14): 143102 (3 pp.). https://doi.org/10.1063/1.2907196
DORA PSI
Dolenc J, Baron R, Missimer JH, Steinmetz MO, van Gunsteren WF
Exploring the conserved water site and hydration of a coiled-coil trimerisation motif: a MD simulation study
ChemBioChem. 2008; 9(11): 1749-1756. https://doi.org/10.1002/cbic.200800096
DORA PSI
Grigoriev I, Gouveia SM, van der Vaart B, Demmers J, Smyth JT, Honnappa S, et al.
STIM1 is a MT-plus-end-tracking protein involved in remodeling of the ER
Current Biology. 2008; 18(3): 177-182. https://doi.org/10.1016/j.cub.2007.12.050
DORA PSI
Grimshaw JPA, Stirnimann CU, Brozzo MS, Malojcic G, Grütter MG, Capitani G, et al.
DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli
Journal of Molecular Biology. 2008; 380(4): 667-680. https://doi.org/10.1016/j.jmb.2008.05.031
DORA PSI
Hartmann S, Missimer JH, Stoeckel C, Abela E, Shah J, Seitz RJ, et al.
Functional connectivity in tactile object discrimination - a principal component analysis of an event related fMRI-study
PLoS One. 2008; 3(12): e3831 (13 pp.). https://doi.org/10.1371/journal.pone.0003831
DORA PSI
Hwang S-J, Kim SH, Kim H-Z, Steinmetz MO, Koh GY, Lee GM
High-level expression and purification of a designed angiopoietin-1 chimeric protein, COMP-Ang1, produced in Chinese hamster ovary cells
Protein Journal. 2008; 27(5): 319-326. https://doi.org/10.1007/s10930-008-9140-5
DORA PSI
Javelle A, Lupo D, Ripoche P, Fulford T, Merrick M, Winkler FK
Substrate binding, deprotonation, and selectivity at the periplasmic entrance of the Escherichia coli ammonia channel AmtB
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2008; 105(13): 5040-5045. https://doi.org/10.1073/pnas.0711742105
DORA PSI
Kawamura H, Li X, Goishi K, van Meeteren LA, Jakobsson L, Cébe-Suarez S, et al.
Neuropilin-1 in regulation of VEGF-induced activation of p38MAPK and endothelial cell organization
Blood. 2008; 112(9): 3638-3649. https://doi.org/10.1182/blood-2007-12-125856
DORA PSI
Licht K, Medenbach J, Lührmann R, Kambach C, Bindereif A
3'-cyclic phosphorylation of U6 snRNA leads to recruitment of recycling factor p110 through LSm proteins
RNA. 2008; 14(8): 1532-1538. https://doi.org/10.1261/rna.1129608
DORA PSI
Manna T, Honnappa S, Steinmetz MO, Wilson L
Suppression of microtubule dynamic instability by the +TIP protein EB1 and its modulation by the CAP-Gly domain of p150^Glued
Biochemistry. 2008; 47(2): 779-786. https://doi.org/10.1021/bi701912g
DORA PSI
Mir M, Álvarez M, Azzaroni O, Tiefenauer L, Knoll W
Molecular architectures for electrocatalytic amplification of oligonucleotide hybridization
Analytical Chemistry. 2008; 80(17): 6554-6559. https://doi.org/10.1021/ac800560t
DORA PSI
Narzi D, Siu SWI, Stirnimann CU, Grimshaw JPA, Glockshuber R, Capitani G, et al.
Evidence for proton shuffling in a thioredoxin-like protein during catalysis
Journal of Molecular Biology. 2008; 382(4): 978-986. https://doi.org/10.1016/j.jmb.2008.07.061
DORA PSI
Nomi JS, Scherfeld D, Friederichs S, Schäfer R, Franz M, Wittsack H-J, et al.
On the neural networks of empathy: a principal component analysis of an fMRI study
Behavioral and Brain Functions. 2008; 4: 41 (13 pp.). https://doi.org/10.1186/1744-9081-4-41
DORA PSI
Puorger C, Eidam O, Capitani G, Erilov D, Grütter MG, Glockshuber R
Infinite kinetic stability against dissociation of supramolecular protein complexes through donor strand complementation
Structure. 2008; 16(4): 631-642. https://doi.org/10.1016/j.str.2008.01.013
DORA PSI
Rennel ES, Hamdollah-Zadeh MA, Wheatley ER, Magnussen A, Schüler Y, Kelly SP, et al.
Recombinant human VEGF₁₆₅b protein is an effective anti-cancer agent in mice
European Journal of Cancer. 2008; 44(13): 1883-1894. https://doi.org/10.1016/j.ejca.2008.05.027
DORA PSI
Soro S, Orecchia A, Morbidelli L, Lacal PM, Morea V, Ballmer-Hofer K, et al.
A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through α5β1 integrin
Blood. 2008; 111(7): 3479-3488. https://doi.org/10.1182/blood-2007-03-077537
DORA PSI
Steinmetz MO, Gattin Z, Verel R, Ciani B, Stromer T, Green JM, et al.
Atomic models of de novo designed ccβ-Met amyloid-like fibrils
Journal of Molecular Biology. 2008; 376(3): 898-912. https://doi.org/10.1016/j.jmb.2007.11.100
DORA PSI
Steinmetz MO, Akhmanova A
Capturing protein tails by CAP-Gly domains
Trends in Biochemical Sciences. 2008; 33(11): 535-545. https://doi.org/10.1016/j.tibs.2008.08.006
DORA PSI
Tiefenauer LX, Studer A
Nano for bio: nanopore arrays for stable and functional lipid bilayer membranes
Biointerphases: A Journal of Biomaterials and Biological Interfaces. 2008; 3(2): FA75-FA79. https://doi.org/10.1116/1.2912932
DORA PSI
Vacca RA, Giannattasio S, Capitani G, Marra E, Christen P
Molecular evolution of B₆ enzymes: binding of pyridoxal-5'-phosphate and Lys41Arg substitution turn ribonuclease A into a model B₆ protoenzyme
BMC Biochemistry. 2008; 9(1): 17 (10 pp.). https://doi.org/10.1186/1471-2091-9-17
DORA PSI
Verel R, Tomka IT, Bertozzi C, Cadalbert R, Kammerer RA, Steinmetz MO, et al.
Polymorphism in an amyloid-like fibril-forming model peptide
Angewandte Chemie International Edition. 2008; 47(31): 5842-5845. https://doi.org/10.1002/anie.200800021
DORA PSI
Zaric BL, Kambach C
Reconstitution of recombinant human LSm complexes for biochemical, biophysical, and cell biological studies
In: Maquat LE, Kiledjian M, eds. RNA turnover in eukaryotes. Nucleases, pathways and analysis of mRNA decay. Methods in enzymology. Elsevier Ltd.; 2008:57-74. https://doi.org/10.1016/S0076-6879(08)02604-9
DORA PSI
Baatout S, Jaussi R, Michaux A, Buset J, Schoonjans W, Jacquet P
Intracellular signal transduction in mouse oocytes and irradiated early embryos
In Vivo. 2007; 21(4): 587-592.
DORA PSI
Bergman N, Moraes KCM, Anderson JR, Zaric B, Kambach C, Schneider RJ, et al.
Lsm proteins bind and stabilize RNAs containing 5′ poly(A) tracts
Nature Structural and Molecular Biology. 2007; 14(9): 824-831. https://doi.org/10.1038/nsmb1287
DORA PSI
Conroy MJ, Durand A, Lupo D, Li X-D, Bullough PA, Winkler FK, et al.
The crystal structure of the Escherichia coli AmtB-GlnK complex reveals how GlnK regulates the ammonia channel
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2007; 104(4): 1213-1218. https://doi.org/10.1073/pnas.0610348104
DORA PSI
Dais C, Solak HH, Ekinci Y, Müller E, Sigg H, Grützmacher D
Ge quantum dot molecules and crystals: preparation and properties
Surface Science. 2007; 601(13): 2787-2791. https://doi.org/10.1016/j.susc.2006.12.053
DORA PSI
Fitzgerald DJ, Schaffitzel C, Berger P, Wellinger R, Bieniossek C, Richmond TJ, et al.
Multiprotein expression strategy for structural biology of eukaryotic complexes
Structure. 2007; 15(3): 275-279. https://doi.org/10.1016/j.str.2007.01.016
DORA PSI
Frey D, Kambach C, Steinmetz MO, Jaussi R
Production of in vitro amplified DNA pseudolibraries and high-throughput cDNA target amplification
BMC Biotechnology. 2007; 7: 31 (5 pp.). https://doi.org/10.1186/1472-6750-7-31
DORA PSI
Grützmacher D, Dais C, Zhang L, Müller E, Solak HH
Templated self-organization of SiGe quantum structures for nanoelectronics
Materials Science and Engineering C: Biomimetic Materials, Sensors and Systems. 2007; 27(5-8): 947-953. https://doi.org/10.1016/j.msec.2006.07.029
DORA PSI
Grützmacher D, Fromherz T, Dais C, Stangl J, Müller E, Ekinci Y, et al.
Three-dimensional Si/Ge quantum dot crystals
Nano Letters. 2007; 7(10): 3150-3156. https://doi.org/10.1021/nl0717199
DORA PSI
Han X, Studer A, Sehr H, Geissbühler I, Di Berardino M, Winkler FK, et al.
Nanopore arrays for stable and functional free-standing lipid bilayers
Advanced Materials. 2007; 19(24): 4466-4470. https://doi.org/10.1002/adma.200700468
DORA PSI
Javelle A, Lupo D, Li X-D, Merrick M, Chami M, Ripoche P, et al.
Reprint of "Structural and mechanistic aspects of Amt/Rh proteins" [J. Struct. Biol. 158 (2007) 472-481]
Journal of Structural Biology. 2007; 159(2): 243-252. https://doi.org/10.1016/S1047-8477(07)00165-7
DORA PSI
Javelle A, Lupo D, Li X-D, Merrick M, Chami M, Ripoche P, et al.
Structural and mechanistic aspects of Amt/Rh proteins
Journal of Structural Biology. 2007; 158(3): 472-481. https://doi.org/10.1016/j.jsb.2007.01.004
DORA PSI
John CM, Hite RK, Weirich CS, Fitzgerald DJ, Jawhari H, Faty M, et al.
The Caenorhabditis elegans septin complex is nonpolar
EMBO Journal. 2007; 26(14): 3296-3307. https://doi.org/10.1038/sj.emboj.7601775
DORA PSI
Kambach C
Pipelines, robots, crystals and biology: what use high throughput solving structures of challenging targets?
Current Protein and Peptide Science. 2007; 8(2): 205-217. https://doi.org/10.2174/138920307780363442
DORA PSI
Koller-Eichhorn R, Marquardt T, Gail R, Wittinghofer A, Kostrewa D, Kutay U, et al.
Human OLA1 defines an ATPase subfamily in the Obg family of GTP-binding proteins
Journal of Biological Chemistry. 2007; 282(27): 19928-19937. https://doi.org/10.1074/jbc.M700541200
DORA PSI
Lupo D, Li X-D, Durand A, Tomizaki T, Cherif-Zahar B, Matassi G, et al.
The 1.3-Å resolution structure of Nitrosomonas europaea Rh50 and mechanistic implications for NH₃ transport by Rhesus family proteins
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2007; 104(49): 19303-19308. https://doi.org/10.1073/pnas.0706563104
DORA PSI
Missimer JH, Steinmetz MO, Baron R, Winkler FK, Kammerer RA, Daura X, et al.
Configurational entropy elucidates the role of salt-bridge networks in protein thermostability
Protein Science. 2007; 16(7): 1349-1359. https://doi.org/10.1110/ps.062542907
DORA PSI
Ruch C, Skiniotis G, Steinmetz MO, Walz T, Ballmer-Hofer K
Structure of a VEGF–VEGF receptor complex determined by electron microscopy
Nature Structural and Molecular Biology. 2007; 14(3): 249-250. https://doi.org/10.1038/nsmb1202
DORA PSI
Scherr N, Honnappa S, Kunz G, Mueller P, Jayachandran R, Winkler F, et al.
Structural basis for the specific inhibition of protein kinase G, a virulence factor of Mycobacterium tuberculosis
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2007; 104(29): 12151-12156. https://doi.org/10.1073/pnas.0702842104
DORA PSI
Severi E, Javelle A, Merrick M
The conserved carboxy-terminal region of the ammonia channel AmtB plays a critical role in channel function
Molecular Membrane Biology. 2007; 24(2): 161-171. https://doi.org/10.1080/09687860601129420
DORA PSI
Steinmetz MO, Jelesarov I, Matousek WM, Honnappa S, Jahnke W, Missimer JH, et al.
Molecular basis of coiled-coil formation
Proceedings of the National Academy of Sciences of the United States of America PNAS. 2007; 104(17): 7062-7067. https://doi.org/10.1073/pnas.0700321104
DORA PSI
Steinmetz MO
Structure and thermodynamics of the tubulin–stathmin interaction
Journal of Structural Biology. 2007; 158(2): 137-147. https://doi.org/10.1016/j.jsb.2006.07.018
DORA PSI
Studer R, Dahinden P, Wang W-W, Auchli Y, Li X-D, Dimroth P
Crystal structure of the carboxyltransferase domain of the oxaloacetate decarboxylase Na⁺ pump from Vibrio cholerae
Journal of Molecular Biology. 2007; 367(2): 547-557. https://doi.org/10.1016/j.jmb.2006.12.035
DORA PSI
Tersar K, Boentert M, Berger P, Bonneick S, Wessig C, Toyka KV, et al.
Mtmr13/Sbf2-deficient mice: an animal model for CMT4B2
Human Molecular Genetics. 2007; 16(24): 2991-3001. https://doi.org/10.1093/hmg/ddm257
DORA PSI
Teuling E, Ahmed S, Haasdijk E, Demmers J, Steinmetz MO, Akhmanova A, et al.
Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates
Journal of Neuroscience. 2007; 27(36): 9801-9815. https://doi.org/10.1523/JNEUROSCI.2661-07.2007
DORA PSI
Weisbrich A, Honnappa S, Jaussi R, Okhrimenko O, Frey D, Jelesarov I, et al.
Structure-function relationship of CAP-Gly domains
Nature Structural and Molecular Biology. 2007; 14(10): 959-967. https://doi.org/10.1038/nsmb1291
DORA PSI
Zehnder-Fjällman AHM, Marty C, Halin C, Hohn A, Schibli R, Ballmer-Hofer K, et al.
Evaluation of anti-VEGFR-3 specific scFv antibodies as potential therapeutic and diagnostic tools for tumor lymph-angiogenesis
Oncology Reports. 2007; 18(4): 933-941. https://doi.org/10.3892/or.18.4.933
DORA PSI
Brem F, Tiefenauer L, Fink A, Dobson J, Hirt AM
A mixture of ferritin and magnetite nanoparticles mimics the magnetic properties of human brain tissue
Physical Review B. 2006; 73(22): 224427 (6 pp.). https://doi.org/10.1103/PhysRevB.73.224427
DORA PSI
Cébe Suarez S, Pieren M, Cariolato L, Arn S, Hoffmann U, Bogucki A, et al.
A VEGF-A splice variant defective for heparan sulfate and neuropilin-1 binding shows attenuated signaling through VEGFR-2
Cellular and Molecular Life Sciences. 2006; 63(17): 2067-2077. https://doi.org/10.1007/s00018-006-6254-9
DORA PSI
Cébe-Suarez S, Zehnder-Fjällman A, Ballmer-Hofer K
The role of VEGF receptors in angiogenesis; complex partnerships
Cellular and Molecular Life Sciences. 2006; 63(5): 601-615. https://doi.org/10.1007/s00018-005-5426-3
DORA PSI
Fitzgerald DJ, Berger P, Schaffitzel C, Yamada K, Richmond TJ, Berger I
Protein complex expression by using multigene baculoviral vectors
Nature Methods. 2006; 3(12): 1021-1032. https://doi.org/10.1038/nmeth983
DORA PSI
Honnappa S, Jahnke W, Seelig J, Steinmetz MO
Control of intrinsically disordered stathmin by multisite phosphorylation
Journal of Biological Chemistry. 2006; 281(23): 16078-16083. https://doi.org/10.1074/jbc.M513524200
DORA PSI
Honnappa S, Okhrimenko O, Jaussi R, Jawhari H, Jelesarov I, Winkler FK, et al.
Key interaction modes of dynamic +TIP networks
Molecular Cell. 2006; 23(5): 663-671. https://doi.org/10.1016/j.molcel.2006.07.013
DORA PSI
Javelle A, Lupo D, Zheng L, Li X-D, Winkler FK, Merrick M
An unusual twin-His arrangement in the pore of ammonia channels is essential for substrate conductance
Journal of Biological Chemistry. 2006; 281(51): 39492-39498. https://doi.org/10.1074/jbc.M608325200
DORA PSI
Kammerer RA, Steinmetz MO
De novo design of a two-stranded coiled-coil switch peptide
Journal of Structural Biology. 2006; 155(2): 146-153. https://doi.org/10.1016/j.jsb.2006.01.017
DORA PSI
Li XD, Lupo D, Zheng L, Winkler F
Structural and functional insights into the AmtB/Mep/Rh protein family
Transfusion Clinique et Biologique. 2006; 13(1-2): 65-69. https://doi.org/10.1016/j.tracli.2006.02.014
DORA PSI
Liu J, Tiefenauer L, Tian S, Nielsen PE, Knoll W
PNA-DNA hybridization study using labeled streptavidin by voltammetry and surface plasmon fluorescence spectroscopy
Analytical Chemistry. 2006; 78(2): 470-476. https://doi.org/10.1021/ac051299c
DORA PSI
Macdonald PR, Progias P, Ciani B, Patel S, Mayer U, Steinmetz MO, et al.
Structure of the extracellular domain of tie receptor tyrosine kinases and localization of the angiopoietin-binding epitope
Journal of Biological Chemistry. 2006; 281(38): 28408-28414. https://doi.org/10.1074/jbc.M605219200
DORA PSI
Marty C, Langer-Machova Z, Sigrist S, Schott H, Schwendener RA, Ballmer-Hofer K
Isolation and characterization of a scFv antibody specific for tumor endothelial marker 1 (TEM1), a new reagent for targeted tumor therapy
Cancer Letters. 2006; 235(2): 298-308. https://doi.org/10.1016/j.canlet.2005.04.029
DORA PSI
Pieren M, Prota AE, Ruch C, Kostrewa D, Wagner A, Biedermann K, et al.
Crystal structure of the Orf virus NZ2 variant of vascular endothelial growth factor-E. Implications for receptor specificity
Journal of Biological Chemistry. 2006; 281(28): 19578-19587. https://doi.org/10.1074/jbc.M601842200
DORA PSI
Siemer AB, Ritter C, Steinmetz MO, Ernst M, Riek R, Meier BH
¹³C, ¹⁵N resonance assignment of parts of the HET-s prion protein in its amyloid form
Journal of Biomolecular NMR. 2006; 34(2): 75-87. https://doi.org/10.1007/s10858-005-5582-7
DORA PSI
Tiefenauer LX
Ethics of nanotechnology in medicine. Challenges and promises
NanoBiotechnology. 2006; 2(1-2): 1-3. https://doi.org/10.1007/s12030-006-0001-z
DORA PSI
Wagner A, Pieren M, Schulze-Briese C, Ballmer-Hofer K, Prota AE
Structure determination of VEGF-E by sulfur SAD
Acta Crystallographica Section D: Structural Biology. 2006; 62(11): 1430-1434. https://doi.org/10.1107/S0907444906036742
DORA PSI
Wang P, Palfi Z, Preusser C, Lücke S, Lane WS, Kambach C, et al.
Sm core variation in spliceosomal small nuclear ribonucleoproteins from Trypanosoma brucei
EMBO Journal. 2006; 25(19): 4513-4523. https://doi.org/10.1038/sj.emboj.7601328
DORA PSI
Weder BJ, Schindler K, Loher TJ, Wiest R, Wissmeyer M, Ritter P, et al.
Brain areas involved in medial temporal lobe seizures: a principal component analysis of ictal SPECT data
Human Brain Mapping. 2006; 27(6): 520-534. https://doi.org/10.1002/hbm.20196
DORA PSI
Zeisberger SM, Odermatt B, Marty C, Zehnder-Fjällman AHM, Ballmer-Hofer K, Schwendener RA
Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach
British Journal of Cancer. 2006; 95(3): 272-281. https://doi.org/10.1038/sj.bjc.6603240
DORA PSI

A conserved trimerization motif controls the topology of short coiled coils Kammerer RA, Kostrewa D, Progias P, Honnappa S, Avila D, Lustig A, Winkler FK, Pieters J, Steinmetz MO
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 102, 13891-13896 (2005).
DOI: 10.1073/pnas.0502390102
Association of the leukocyte plasma membrane with the actin cytoskeleton through coiled coil-mediated trimeric coronin 1 molecules Gatfield J, Albrecht I, Zanolari B, Steinmetz MO, Pieters J
MOLECULAR BIOLOGY OF THE CELL 16, 2786-2798 (2005).
Design of a coiled-coil-based model peptide system to explore the fundamentals of amyloid fibril formation Steinmetz MO, Garcia-Echeverria C, Kammerer RA
International Journal of Peptide Research and Therapeutics 11, 43-52 (2005).
DOI: 10.1007/s10989-004-1720-4
Molecular-dynamics simulations of C- and N-terminal peptide derivatives of GCN4-p1 in aqueous solution Missimer JH, Steinmetz MO, Jahnke W, Winkler FK, van Gunsteren WF, Daura X
Chemistry & Biodiversity 2, 1086-1104 (2005).
Oligomerization and multimerization are critical for angiopoietin-1 to bind and phosphorylate Tie2 Kim KT, Choi HH, Steinmetz MO, Maco B, Kammerer RA, Ahn SY, Kim HZ, Lee GM, Koh GY
JOURNAL OF BIOLOGICAL CHEMISTRY 280, 20126-20131 (2005).
DOI: 10.1074/jbc.M500292200
Structural and functional analysis of coronin 1 Albrecht I, Gatfield J, Zanolari B, Steinmetz MO, Pieters J
FEBS JOURNAL 272, 320-321 (2005).
Structural basis for the regulation of tubulin by vinblastine Gigant B, Wang CG, Ravelli RBG, Roussi F, Steinmetz MO, Curmi PA, Sobel A, Knossow M
NATURE 435, 519-522 (2005).
DOI: 10.1038/nature03566
Structural insights into the EB1-APC interaction Honnappa S, John CM, Kostrewa D, Winkler FK, Steinmetz MO
EMBO JOURNAL 24, 261 (2005).
DOI: 10.1038/sj.emboj.7600529
Structural insights into the EB1-APC interaction (vol 24, pg 261, 2005) Honnappa S, John CM, Kostrewa D, Winkler FK, Steinmetz MO
EMBO JOURNAL 24, 872-872 (2005).
DOI: 10.1038/sj.emboj.7600590
A Molecular Dynamics Study of Reovirus Attachment Protein ?1 Reveals Conformational Changes in ?1 Structure Cavalli A, Prota AE, Stehle T, Dermody Terence S, Recanatini M, Folkers G, Scapozza L
BIOPHYSICAL JOURNAL 86, 3423 (2004).
DOI: 10.1529/biophysj.103.030825
COMP-Ang1: A designed angiopoietin-1 variant with nonleaky angiogenic activity Cho CH, Kammerer RA, Lee HJ, Steinmetz MO, Ryu YS, Lee SH, Yasunaga K, Kim KT, Kim I, Choi HH, Kim W, Kim SH, Park SK, Lee GM, Koh GY
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101, 5547-5552 (2004).
DOI: 10.1073/pnas.0307574101
Exploring amyloid formation by a de novo design Kammerer RA, Kostrewa D, Zurdo J, Detken A, Garcia-Echeverria C, Green JD, Muller SA, Meier BH, Winkler FK, Dobson CM, Steinmetz MO
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101, 4435-4440 (2004).
DOI: 10.1073/pnas.0306786101
Crystal structure of human junctional adhesion molecule 1: Implications for reovirus binding Prota AE, Campbell JA, Schelling P, Forrest JC, Watson MJ, Peters TR, Aurrand-Lions M, Imhof BA, Dermody TS, Stehle T
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 100, 5366 (2003).
DOI: 10.1073/pnas.0937718100
Thermodynamics of the Op18/stathmin-tubulin interaction Honnappa S, Cutting B, Jahnke W, Seelig J, Steinmetz MO
JOURNAL OF BIOLOGICAL CHEMISTRY 278, 38926-38934 (2003).
DOI: 10.1074/jbc.M305546200
The crystal structure of human CD21: Implications for Epstein-Barr virus and C3d binding Prota AE, Sage DR, Stehle T, Fingeroth JD
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 99, 10641 (2002).
DOI: 10.1073/pnas.162360499

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Dr. Jörg Standfuss

Head a. i. and Group Leader Laboratory of Biomolecular Research

joerg.standfuss@psi.ch

+41 56 310 25 86

Anita Strittmatter Hähnke

Secretary

anita.strittmatter@psi.ch

+41 56 310 20 35

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Publications pre-2020

The list below shows the publications before 2020. You can find the publications from 2020 onwards here.

Publication Pre-2020

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