Lab News & Scientific Highlights

Whitlockite in mammary microcalcifications

Whitlockite in mammary microcalcifications is not associated with breast cancer

Microcalcifications, small deposits of calcium-containing minerals that form in breast tissue, are often, but not always, a warning sign of breast cancer. The relationship between microcalcifications and cancer has not been fully understood thus far. Researchers discovered now that the relationship between microcalcifications and tumors seems to be linked to the presence of a particular mineral called whitlockite, which is rich in magnesium and is found in microcalcifications only in the absence of tumors.

Pacific cleaner shrimp

Bright white coloring of Pacific cleaner shrimp revelead

In a study published in Nature Photonics, researchers at the Ben-Gurion University of the Negev, Israel, explain the bright, white-colored stripes from Pacific cleaner shrimps, one of the most efficient white reflectors found in nature.

first_beam_after_FE

Progress of the X06DA-PXIII beamline upgrade: First light in the optics hutch

On June 7, 2023, the PXIII project team successfully shone the first light into the optics hutch at the upgraded X06DA-PXIII beamline. It is an essential first step for testing new hardware and software solutions that will be implemented at SLS2.0.

Cement hydration on the micro- and nanoscale

A deep look into hydration of cement

Researchers led by the University of Málaga show the Portland cement early age hydration with microscopic detail and high contrast between the components. This knowledge may contribute to more environmentally friendly manufacturing processes.

Manuel Guizar-Sicairos at SLS

Manuel Guizar-Sicairos appointed as Associate Professor at EPF Lausanne and head of the Computational X-ray Imaging group at PSI

Dr. Manuel Guizar-Sicairos, currently Senior Scientist at PSI, was appointed as Associate Professor of Physics in EPF Lausanne and head of the Computational X-ray Imaging group in PSI.

SPIE Fellow Manuel Guizar-Sicairos

Dr. Manuel Guizar-Sicairos elected as SPIE Fellow member

Dr. Manuel Guizar-Sicairos was elected as a 2022 SPIE Fellow Member for his contributions to coherent lensless imaging, including ptychography and X-ray nano-tomography. The distinction was awarded in the SPIE’s Optics & Photonics conference in San Diego, California.

Hercules School 2022 group photo

Hercules School 2022

PSI hosted again the Hercules School in March 2022. We had the pleasure to welcome 20 international PhD students, PostDocs and scientists to demonstrate our state-of-the-art techniques and methodologies at our large scale facilities, the Swiss Light Source (SLS), the Swiss Spallation Neutron Source (SINQ) and our free electron laser SwissFEL.

perovskite_3

Lighting up the appealing world of hybrid perovskites

Researchers from Italy, in collaboration with the Paul Scherrer Institut, successfully used the macromolecular crystallography beamline X06DA-PXIII at the Swiss Light Source to characterize promising perovkites materials used in solar cells and other photodetector devices.

Revealing invisible defects in fusion reactor armor

Revealing invisible defects in fusion reactor armor

In an exciting collaboration, Nick Phillips, a PSI Fellow at the cSAXS beamline, reveals nanoscale lattice distortions created by invisible defects in fusion reactor armor. This work develops the current understanding of how the smallest, but most prevalent defects, generated during neutron irradiation behave. The novel Bragg ptychographic approach published in Nature Communications paves the way for fast, robust, 3D Bragg ptychography.

Spatially resolved likelihood for glycation of collagen

Glycation of collagen: Quantifying rates

Collagen is abundant in the connective tissue of human beings, e.g. in tendons, ligament and cornea. Glycation of collagen distorts its structure, renders the extracellular matrix stiff and brittle and at the same time lowers the degradation susceptibility thereby preventing renewal. Based on models and with parameters determined from experimental data, we describe the glycation of type 1 collagen in bovine pericardium derived bio-tissues upon incubation in glucose and ribose. We hope that this contributes to a better quantitative understanding of the effects of diabetes on collagen.

Guizar-Sicairos ICO prize ceremony

Dr. Manuel Guizar-Sicairos is awarded ICO prize

Dr. Manuel Guizar-Sicairos, beamline scientist at the cSAXS beamline, is the 2019 recipient of the International Commission for Optics (ICO) Prize. The distinction was awarded in the EOSAM conference in Rome.

3D reconstruction of an entire adult mouse brain vasculature.

Hierarchical imaging and computational analysis of three-dimensional vascular network architecture in mouse brain

An international team involving researchers from the University and University Hospital Zürich, the Krembil Research Institute and the University and University Hospital in Toronto (Canada), the Department of Physics of Jyväskylä (Finland), the University of Leuven (Belgium), the Johannes Kepler University in Linz (Austria), the Novartis Institutes for Biomedical Research in Emeryville (USA), the ETH Zürich and the Paul Scherrer Institute has developed a protocol that enables hierarchical imaging and computational analysis of vascular networks in entire postnatal- and adult mouse brains, enabling direct and quantitative comparisons of the morphological brain vascular network architecture between different postnatal and / or adult developmental stages. The results have been published on Nature Protocols on September 3rd, 2021.