Scientific Highlights

Prediction of the mechanical properties dictated by the local microfiber orientation is essential for the performance characterization of fiber-reinforced composites. Typically, tomographic imaging methods that provide fine spatial resolution are employed to investigate various materials' local micro- and nano-architecture in a non-destructive manner. However, conventional imaging techniques are limited by a substantial trade-off between the structure size of interest and the accessible field of view (FOV). Researchers from the TOMCAT beamline at Paul Scherrer Institut, Xnovo Technology ApS, and the Technical University of Denmark have demonstrated the potential of X-ray scattering tensor tomography for industrial applications by characterizing the microstructure of a centimeter-sized industrially relevant freeform injection molding fiber-reinforced composite sample. This emerging technique provides unprecedented access to microstructural information over centimeter-sized sample volumes paving the way towards its potential integration as an invaluable tool, for instance, in the fiber-reinforced-composite (FRC) industry. The obtained fiber orientation and anisotropy information over statistically relevant large volumes can be used to predict the mechanical properties of final products, optimize production parameters, and improve fiber injection molding simulation frameworks. The work is published in Composites Part B: Engineering on 15 March 2022.

An international team involving researchers from the University and University Hospital Zürich, the Krembil Research Institute and the University and University Hospital in Toronto (Canada), the Department of Physics of Jyväskylä (Finland), the University of Leuven (Belgium), the Johannes Kepler University in Linz (Austria), the Novartis Institutes for Biomedical Research in Emeryville (USA), the ETH Zürich and the Paul Scherrer Institute has developed a protocol that enables hierarchical imaging and computational analysis of vascular networks in entire postnatal- and adult mouse brains, enabling direct and quantitative comparisons of the morphological brain vascular network architecture between different postnatal and / or adult developmental stages. The results have been published on Nature Protocols on September 3rd, 2021.

Researchers from the University of Oxford, the Diamond Light Source and the Paul Scherrer Institut have generated strong evidence supporting one of two competing theories regarding the mechanism by which lithium metal dendrites grow through ceramic electrolytes. A process leading to short circuit at high rates of charge. The X-ray phase-contrast imaging capabilities of the TOMCAT beamline of the Swiss light source allowed researchers to visualize and characterize the growth of cracks and dendrites deep within an operating solid-state battery. The results were published in Nature Materials on April 22, 2021.

A group of EMPA and ETH Zürich researchers have developed a new method to directly write ink made of silica aerogels in 3D. Thanks to X-ray phase contrast tomography at the TOMCAT beamline they characterized the resulting printed material with different compositions. Their results were published in Nature on August 18, 2020.

Metal-based nanoparticles are a promising tool in medicine – as a contrast agent, transporter of active substances, or to thermally kill tumor cells. Up to now, it has been hardly possible to study their distribution inside an organism. Researchers at the University of Basel in collaboration with the TOMCAT team have used phase contrast X-ray tomographic microscopy to take high-resolution captures of the nanoparticle aggregation inside zebrafish embryos.

The study was published in the journal Small and featured on the cover of its current issue.

The team of Prof. Thomas Hermans at the University of Strasbourg in France managed to create wall-less aqueous liquid channels called anti-tubes. Thanks to X-ray phase contrast tomography at the TOMCAT beamline those anti-tubes could be observed in 3D. The exciting results were published in Nature on May 6, 2020.

The TOMCAT beamline at the Swiss Light Source specializes in rapid high-resolution 3-dimensional tomographic microscopy measurements with a strong focus on biomedical imaging. The team has recently developed a technique to acquire micrometer-scale resolution datasets on the entire lung structure of a juvenile rat in its fresh natural state within the animal’s body and without the need for any fixation, staining or other alteration that would affect the observed structure (E. Borisova et al., 2020, Histochem Cell Biol).

The grating fabrication team of the X-ray tomography group has scored another record in etching technology of silicon by realizing a MacEtch process in gas phase. Ultra-high aspect ratios (up to 10 000 : 1) in the nanoscale regime (down to 10 nm) were achieved by platinum assisted chemical etching of silicon in the gas phase. The results were published in Nanoscale Horizons on February 17, 2020.

Detailed characterization of cellular structure and development of exceptionally preserved ancient tiny fossils from South China by synchrotron based X-ray tomographic microscopy at TOMCAT led an international team of researchers from the University of Bristol and Nanjing Institute of Geology and Palaeontology to the discovery that animal-like embryos evolved long before the first animals appear in the fossil record.

Researchers from the Helmholtz Zentrum Berlin (HZB) and the TOMCAT beamline have achieved a new world record in time-resolved tomography by measuring over 200 tomographies per second during heating of an evolving aluminium metal foam.

Synchrotron-based X-ray tomographic microscopy of melanophores (skin pigment cells) of an amazingly well preserved 180 million years old ichtyosaur (extinct marine reptile similar to whales) contributed in a multidisciplinary investigation to the new findings published today in Nature.

Researchers at the Paul Scherrer Institute's Swiss Light Source in Villigen, Switzerland, have developed an X-ray grating interferometry setup which does not require an analyzer grating, by directly detecting the fringes generated by the phase grating with a high resolution detector. The 25um pitch GOTTHARD microstrip detector utilizes a direct conversion sensor in which the charge generated from a single absorbed photon is collected by more than one channel. Therefore it is possible to interpolate to achieve a position resolution finer than the strip pitch.

In order to understand limitations in current battery materials and systematically engineer better ones, it is helpful to be able to directly visualize the lithium dynamics in materials during battery charge and discharge. Researchers at ETH Zurich and Paul Scherrer Institute have demonstrated a way to do this.

The discovery of exceptionally well-preserved, tiny fossil seeds dating back to the Early Cretaceous corroborates that flowering plants were small opportunistic colonizers at that time, according to a new Yale-led study.

Researchers at PSI have developed a technique that combines tomography measurements at different resolution levels to allow quantitative interpretation for nanoscale tomography on an interior region of interest of the sample. In collaboration with researchers of the institute AMOLF in the Netherlands and ETH Zurich in Switzerland they showcase their technique by studying the porous structure within a section of an avian eggshell. The detailed measurements of the interior of the sample allowed the researchers to quantify the ordering and distribution of an intricate network of pores within the shell.