Research
Main interest:
Functional Surfaces and Surface Functionalization
Research Focus:
Combination of advanced micro- and nanostructuring techniques with surface chemistry to obtain surfaces with specific properties.
- Polymer grafting
- Creation of nanostructured polymer brushes
- Adaptation of surface properties of polymer materials
- Adaptive and switchable surface properties
- Designed surfaces for bio-applications
- Micro- and nanopatterns of functional proteins
- Designed surface topographies for implant research
- Supports for Protein Crystallography
- Thin-film supports for XFEL-based protein crystallography
- Nanostructured substrates to induce protein crystallization
Teaching
2015-2019: Chemistry I in the Materials Science Bachelor Degree Course at ETHZ
Publications
Polymer Micro and Nanografting (Book)
Celestino Padeste und Sonja Neuhaus
Polymer Micro- and Nanografting
Based on own work and literature reports this book provides a summary of strategies for the formation of functional polymer patterns and structures on or in polymeric substrates using grafting processes.
Elsevier 2015; ISBN: 978-0-323-35322-9
Online Edition Elsevier Book Store
Papers (since 2004)
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Mortelmans T, Marty B, Kazazis D, Padeste C, Li X, Ekinci Y
Three-dimensional microfluidic capillary device for rapid and multiplexed immunoassays in whole blood
ACS Sensors. 2024; 9(5): 2455-2464. https://doi.org/10.1021/acssensors.4c00153
DORA PSI -
Gotthard G, Flores-Ibarra A, Carrillo M, Kepa MW, Mason TJ, Stegmann DP, et al.
Fixed-target pump–probe SFX: eliminating the scourge of light contamination
IUCrJ. 2024; 11(5): 1-13. https://doi.org/10.1107/S2052252524005591
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Moazeni M, Berger P, Padeste C
Polymer brush structures functionalized with molecular beacon for point-of-care diagnostics
Micro and Nano Engineering. 2023; 19: 100184 (9 pp.). https://doi.org/10.1016/j.mne.2023.100184
DORA PSI -
Carrillo M, Mason TJ, Karpik A, Martiel I, Kepa MW, McAuley KE, et al.
Micro-structured polymer fixed targets for serial crystallography at synchrotrons and XFELs
IUCrJ. 2023; 10(6): 678-693. https://doi.org/10.1107/S2052252523007595
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Alpert PA, Boucly A, Yang S, Yang H, Kilchhofer K, Luo Z, et al.
Ice nucleation imaged with X-ray spectro-microscopy
Environmental Science: Atmospheres. 2022; 2(3): 335-351. https://doi.org/10.1039/D1EA00077B
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Mortelmans T, Kazazis D, Padeste C, Berger P, Li X, Ekinci Y
Poly(methyl methacrylate)-based nanofluidic device for rapid and multiplexed serological antibody detection of SARS-CoV-2
ACS Applied Nano Materials. 2022; 5(1): 517-526. https://doi.org/10.1021/acsanm.1c03309
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Martiel I, Beale JH, Karpik A, Huang C-Y, Vera L, Olieric N, et al.
Versatile microporous polymer-based supports for serial macromolecular crystallography
Acta Crystallographica Section D: Structural Biology. 2021; 77(9): 1153-1167. https://doi.org/10.1107/S2059798321007324
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Tran HT, Lucas MS, Ishikawa T, Shahmoradian SH, Padeste C
A compartmentalized neuronal cell-culture platform compatible with cryo-fixation by high-pressure freezing for ultrastructural imaging
Frontiers in Neuroscience. 2021; 15: 726763 (15 pp.). https://doi.org/10.3389/fnins.2021.726763
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Martiel I, Mozzanica A, Opara NL, Panepucci E, Leonarski F, Redford S, et al.
X-ray fluorescence detection for serial macromolecular crystallography using a JUNGFRAU pixel detector
Journal of Synchrotron Radiation. 2020; 27: 329-339. https://doi.org/10.1107/S1600577519016758
DORA PSI -
Mortelmans T, Kazazis D, Guzenko VA, Padeste C, Braun T, Li X, et al.
Grayscale e-beam lithography: effects of a delayed development for well-controlled 3D patterning
Microelectronic Engineering. 2020; 225: 111272 (5 pp.). https://doi.org/10.1016/j.mee.2020.111272
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Karpik A, Martiel I, Kristiansen PM, Padeste C
Fabrication of ultrathin suspended polymer membranes as supports for serial protein crystallography
Micro and Nano Engineering. 2020; 7: 100053 (6 pp.). https://doi.org/10.1016/j.mne.2020.100053
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Makita M, Vartiainen I, Mohacsi I, Caleman C, Diaz A, Jönsson HO, et al.
Femtosecond phase-transition in hard x-ray excited bismuth
Scientific Reports. 2019; 9(1): 602 (7 pp.). https://doi.org/10.1038/s41598-018-36216-3
DORA PSI -
Górzny MŁ, Opara NL, Guzenko VA, Cadarso VJ, Schift H, Li XD, et al.
Microfabricated silicon chip as lipid membrane sample holder for serial protein crystallography
Micro and Nano Engineering. 2019; 3: 31-36. https://doi.org/10.1016/j.mne.2019.03.002
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Szmyt W, Calame M, Padeste C, Dransfeld C
Nanoengineering of fibre surface for carbon fibre-carbon nanotube hierarchical composites
In: Mouritz A, Wang C, Fox B, eds. Proceedings of the 2019 international conference on composite materials (ICCM 2019). Melbourne, Australia: RMIT University; 2019:(9 pp.). www.iccm-central.org/Proceedings/ICCM22proceedings/papers/ICCM22_Full_Paper_260.pdf.
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Moradi M, Opara NL, Tulli LG, Wäckerlin C, Dalgarno SJ, Teat SJ, et al.
Supramolecular architectures of molecularly thin yet robust free-standing layers
Science Advances. 2019; 5(2): eaav4489 (7 pp.). https://doi.org/10.1126/sciadv.aav4489
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Casadei CM, Nass K, Barty A, Hunter MS, Padeste C, Tsai C-J, et al.
Structure-factor amplitude reconstruction from serial femtosecond crystallography of two-dimensional membrane-protein crystals
IUCrJ. 2019; 6: 34-45. https://doi.org/10.1107/S2052252518014641
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Ranamukhaarachchi SA, Padeste C, Häfeli UO, Stoeber B, Cadarso VJ
Design considerations of a hollow microneedle-optofluidic biosensing platform incorporating enzyme-linked assays
Journal of Micromechanics and Microengineering. 2018; 28(2): 024002 (9 pp.). https://doi.org/10.1088/1361-6439/aa9c9c
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Casadei CM, Tsai C-J, Barty A, Hunter MS, Zatsepin NA, Padeste C, et al.
Resolution extension by image summing in serial femtosecond crystallography of two-dimensional membrane-protein crystals
IUCrJ. 2018; 5(1): 103-117. https://doi.org/10.1107/S2052252517017043
DORA PSI -
Seniutinas G, Weber A, Padeste C, Sakellari I, Farsari M, David C
Beyond 100 nm resolution in 3D laser lithography — post processing solutions
Microelectronic Engineering. 2018; 191: 25-31. https://doi.org/10.1016/j.mee.2018.01.018
DORA PSI -
Opara NL, Mohacsi I, Makita M, Castano-Diez D, Diaz A, Juranić P, et al.
Demonstration of femtosecond X-ray pump X-ray probe diffraction on protein crystals
Structural Dynamics. 2018; 5(5): 054303 (15 pp.). https://doi.org/10.1063/1.5050618
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Szmyt W, Marot L, Calame M, Padeste C, Dransfeld C
Carbon fibre-carbon nanotube multiscale composites - nanoengineering of the fibre surface for protection in extreme processing conditions
In: 18th European conference on composite materials (ECCM-18). Patras: Applied Mechanics Laboratory; 2018:(9 pp.).
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Opara N, Martiel I, Arnold SA, Braun T, Stahlberg H, Makita M, et al.
Direct protein crystallization on ultrathin membranes for diffraction measurements at X-ray free-electron lasers
Journal of Applied Crystallography. 2017; 50(3): 909-918. https://doi.org/10.1107/S1600576717005799
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Dübner M, Naoum M-E, Spencer ND, Padeste C
From pH- to light-response: postpolymerization modification of polymer brushes grafted onto microporous polymeric membranes
ACS Omega. 2017; 2(2): 455-461. https://doi.org/10.1021/acsomega.6b00394
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Duebner M, Cadarso VJ, Padeste C
Photonic lab-on-a-chip device with UV light responsive smart surfaces
In: International conference on solid-state sensors, actuators and microsystems. TRANSDUCERS 2017 - 19th international conference on solid-state sensors, actuators and microsystems. Piscataway, New Jersey: Institute of Electrical and Electronics Engineers; 2017:2199 (4 pp.)-2202. https://doi.org/10.1109/TRANSDUCERS.2017.7994513
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Dübner M, Cadarso VJ, Gevrek TN, Sanyal A, Spencer ND, Padeste C
Reversible light-switching of enzymatic activity on orthogonally functionalized polymer brushes
ACS Applied Materials and Interfaces. 2017; 9(11): 9245-9249. https://doi.org/10.1021/acsami.7b01154
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Panzarasa G, Dübner M, Pifferi V, Soliveri G, Padeste C
ON/OFF switching of silicon wafer electrochemistry by pH-responsive polymer brushes
Journal of Materials Chemistry C. 2016; 4(26): 6287-6294. https://doi.org/10.1039/c6tc01822j
DORA PSI -
Arnold SA, Albiez S, Opara N, Chami M, Schmidli C, Bieri A, et al.
Total sample conditioning and preparation of nanoliter volumes for electron microscopy
ACS Nano. 2016; 10(5): 4981-4988. https://doi.org/10.1021/acsnano.6b01328
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Gajos K, Guzenko VA, Dübner M, Haberko J, Budkowski A, Padeste C
Electron-beam lithographic grafting of functional polymer structures from fluoropolymer substrates
Langmuir. 2016; 32(41): 10641-10650. https://doi.org/10.1021/acs.langmuir.6b02808
DORA PSI -
Ranamukhaarachchi SA, Padeste C, Dübner M, Häfeli UO, Stoeber B, Cadarso VJ
Integrated hollow microneedle-optofluidic biosensor for therapeutic drug monitoring in sub-nanoliter volumes
Scientific Reports. 2016; 6: 29075 (10 pp.). https://doi.org/10.1038/srep29075
DORA PSI -
Padeste C, Neuhaus S
Polymer micro- and nanografting
Waltham: Elsevier; 2015. https://doi.org/10.1016/C2014-0-00670-3
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Panneels V, Wu W, Tsai C-J, Nogly P, Rheinberger J, Jaeger K, et al.
Time-resolved structural studies with serial crystallography: a new light on retinal proteins
Structural Dynamics. 2015; 2(4): 041718 (8 pp.). https://doi.org/10.1063/1.4922774
DORA PSI -
Dübner M, Gevrek TN, Sanyal A, Spencer ND, Padeste C
Fabrication of thiol-ene "clickable" copolymer-brush nanostructures on polymeric substrates via extreme ultraviolet interference lithography
ACS Applied Materials and Interfaces. 2015; 7(21): 11337-11345. https://doi.org/10.1021/acsami.5b01804
DORA PSI -
Huang J, Fan D, Ekinci Y, Padeste C
Fabrication of ultrahigh resolution metal nanowires and nanodots through EUV interference lithography
Microelectronic Engineering. 2015; 141: 32-36. https://doi.org/10.1016/j.mee.2015.01.016
DORA PSI -
Özçelik H, Padeste C, Hasirci V
Systematically organized nanopillar arrays reveal differences in adhesion and alignment properties of BMSC and Saos-2 cells
Colloids and Surfaces B: Biointerfaces. 2014; 119: 71-81. https://doi.org/10.1016/j.colsurfb.2014.03.019
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Padeste C, Bellini S, Siewert D, Schift H
Anti-sticking layers for nickel-based nanoreplication tools
Microelectronic Engineering. 2014; 123: 23-27. https://doi.org/10.1016/j.mee.2014.03.039
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Dübner M, Spencer ND, Padeste C
Light-responsive polymer surfaces via postpolymerization modification of grafted polymer-brush structures
Langmuir. 2014; 30(49): 14971-14981. https://doi.org/10.1021/la503388j
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Waser-Althaus J, Salamon A, Waser M, Padeste C, Kreutzer M, Pieles U, et al.
Differentiation of human mesenchymal stem cells on plasma-treated polyetheretherketone
Journal of Materials Science: Materials in Medicine. 2014; 25(2): 515-525. https://doi.org/10.1007/s10856-013-5072-5
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Pedrini B, Tsai C-J, Capitani G, Padeste C, Hunter MS, Zatsepin NA, et al.
7 Å resolution in protein two-dimensional-crystal X-ray diffraction at Linac Coherent Light Source
Philosophical Transactions of the Royal Society B: Biological Sciences. 2014; 369(1647): 20130500 (5 pp.). https://doi.org/10.1098/rstb.2013.0500
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Frank M, Carlson DB, Hunter MS, Williams GJ, Messerschmidt M, Zatsepin NA, et al.
Femtosecond X-ray diffraction from two-dimensional protein crystals
IUCrJ. 2014; 1: 95-100. https://doi.org/10.1107/S2052252514001444
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Rath T, Padeste C, Vockenhuber M, Fradler C, Edler M, Reichmann A, et al.
Direct extreme UV-lithographic conversion of metal xanthates into nanostructured metal sulfide layers for hybrid photovoltaics
Journal of Materials Chemistry A. 2013; 1(37): 11135-11140. https://doi.org/10.1039/c3ta12592k
DORA PSI -
Neuhaus S, Spencer ND, Padeste C
Anisotropic wetting of microstructured surfaces as a function of surface chemistry
ACS Applied Materials and Interfaces. 2012; 4(1): 123-130. https://doi.org/10.1021/am201104q
DORA PSI -
Althaus J, Padeste C, Köser J, Pieles U, Peters K, Müller B
Nanostructuring polyetheretherketone for medical implants
European Journal of Nanomedicine. 2012; 4(1): 7-15. https://doi.org/10.1515/ejnm-2011-0001
DORA PSI -
Althaus J, Urwyler P, Padeste C, Heuberger R, Deyhle H, Schift H, et al.
Micro- and nanostructured polymer substrates for biomedical applications
In: Lakhtakia A, Raúl J. M-P, eds. Bioinspiration, biomimetics, and bioreplication 2012. Vol. 8339. Proceedings of SPIE. Bellingham, WA, USA: SPIE; 2012:83390Q (16 pp.). https://doi.org/10.1117/12.915235
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Neuhaus S, Padeste C, Spencer ND
Functionalization of fluropolymers and polyolefins via grafting of polyelectrolyte brushes from atmospheric-pressure plasma activated surfacesa
Plasma Processes and Polymers. 2011; 8(6): 512-522. https://doi.org/10.1002/ppap.201000175
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Guzenko VA, Ziegler J, Savouchkina A, Padeste C, David C
Fabrication of large scale arrays of metallic nanodots by means of high resolution e-beam lithography
Microelectronic Engineering. 2011; 88(8): 1972 (3 pp.). https://doi.org/10.1016/j.mee.2011.02.042
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Padeste C, Özelik H, Ziegler J, Schleunitz A, Bednarzik M, Yücel D, et al.
Replication of high aspect ratio pillar array structures in biocompatible polymers for tissue engineering applications
Microelectronic Engineering. 2011; 88(8): 1836-1839. https://doi.org/10.1016/j.mee.2010.11.051
DORA PSI -
Neuhaus S, Padeste C, Spencer ND
Versatile wettability gradients prepared by chemical modification of polymer brushes on polymer foils
Langmuir. 2011; 27(11): 6855-6861. https://doi.org/10.1021/la2005908
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Neuhaus S, Padeste C, Solak HH, Spencer ND
Functionalization of fluoropolymer surfaces with nanopatterned polyelectrolyte brushes
Polymer. 2010; 51(18): 4037-4043. https://doi.org/10.1016/j.polymer.2010.07.002
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Nygård K, Satapathy DK, Perret E, Padeste C, Bunk O, David C, et al.
Surface-specific ordering of reverse micelles in confinement
Soft Matter. 2010; 6(18): 4536-4539. https://doi.org/10.1039/c0sm00296h
DORA PSI -
Savouchkina A, Foelske-Schmitz A, Kötz R, Wokaun A, Scherer GG, Padeste C, et al.
Extreme ultraviolet interference lithography for generation of platinum nanoparticles on glassy carbon
In: Bock C, Li J, Traversa E, eds. Vol. 25. ECS transactions. Pennington, NJ: The Electrochemical Society; 2010:175-184. https://doi.org/10.1149/1.3316124
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Auzelyte V, Dais C, Farquet P, Grützmacher D, Heyderman LJ, Luo F, et al.
Extreme ultraviolet interference lithography at the Paul Scherrer Institut
Journal of Micro/Nanolithography, MEMS, and MOEMS. 2009; 8(2): 021204 (10 pp.). https://doi.org/10.1117/1.3116559
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Kappenberger P, Luo F, Heyderman LJ, Solak HH, Padeste C, Brombacher C, et al.
Template-directed self-assembled magnetic nanostructures for probe recording
Applied Physics Letters. 2009; 95(2): 023116 (3 pp.). https://doi.org/10.1063/1.3176937
DORA PSI -
Herzen J, Donath T, Pfeiffer F, Bunk O, Padeste C, Beckmann F, et al.
Quantitative phase-contrast tomography of a liquid phantom using a conventional x-ray tube source
Optics Express. 2009; 17(12): 10010-10018. https://doi.org/10.1364/OE.17.010010
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Trabadelo V, Retolaza A, Merino S, Cruz A, Heredia P, Foelske A, et al.
Protein patterning by thermal nanoimprint lithography and NH3-plasma functionalization of polystyrene
Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 2009; 27(3): 1060-1062. https://doi.org/10.1116/1.3123304
DORA PSI -
Bunk O, Satapathy DK, Pfeiffer F, Diaz A, David C, Nygård K, et al.
Concentration profiles of colloidal fluids in one-dimensional confinement
Chimia. 2008; 62(10): 789-792. https://doi.org/10.2533/chimia.2008.789
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Farquet P, Padeste C, Solak HH, Alkan Gürsel S, Scherer GG, Wokaun A
Extreme UV radiation grafting of glycidyl methacrylate nanostructures onto fluoropolymer foils by RAFT-mediated polymerization
Macromolecules. 2008; 41(17): 6309-6316. https://doi.org/10.1021/ma800202b
DORA PSI -
Farquet P, Padeste C, Börner M, Ben youcef H, Alkan Gürsel S, Scherer GG, et al.
Microstructured proton-conducting membranes by synchrotron-radiation-induced grafting
Journal of Membrane Science. 2008; 325(2): 658-664. https://doi.org/10.1016/j.memsci.2008.08.040
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Zoller FA, Padeste C, Ekinci Y, Solak HH, Engel A
Nanostructured substrates for high density protein arrays
Microelectronic Engineering. 2008; 85(5-6): 1370-1374. https://doi.org/10.1016/j.mee.2007.12.061
DORA PSI -
Farquet P, Kunze A, Padeste C, Solak HH, Gürsel SA, Scherer GG, et al.
Influence of the solvent viscosity on surface graft-polymerization reactions
Polymer. 2007; 48(17): 4936-4942. https://doi.org/10.1016/j.polymer.2007.06.052
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Bunk O, Diaz A, Pfeiffer F, David C, Padeste C, Keymeulen H, et al.
Confinement-induced liquid ordering investigated by x-ray phase retrieval
Physical Review E. 2007; 75(2): 021501 (6 pp.). https://doi.org/10.1103/PhysRevE.75.021501
DORA PSI -
Ekinci Y, Solak HH, Padeste C, Gobrecht J, Stoykovich MP, Nealey PF
20 nm line/space patterns in HSQ fabricated by EUV interference lithography
Microelectronic Engineering. 2007; 84(5-8): 700-704. https://doi.org/10.1016/j.mee.2007.01.213
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Farquet P, Padeste C, Solak HH, Gürsel SA, Scherer GG, Wokaun A
EUV lithographic radiation grafting of thermo-responsive hydrogel nanostructures
Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 2007; 265(1): 187-192. https://doi.org/10.1016/j.nimb.2007.08.070
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Padeste C, Farquet P, Solak HH
Surface relief polymer structures grafted onto polymer films
Microelectronic Engineering. 2006; 83(4-9): 1265-1268. https://doi.org/10.1016/j.mee.2006.01.152
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Padeste C, Farquet P, Potzner C, Solak HH
Nanostructured bio-functional polymer brushes
Journal of Biomaterials Science, Polymer Edition. 2006; 17(11): 1285-1300. https://doi.org/10.1163/156856206778667505
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Park S, Saxer S, Padeste C, Solak HH, Gobrecht J, Schift H
Chemical patterning of sub-50-nm half pitches via nanoimprint lithography
Microelectronic Engineering. 2005; 78-79(1-4): 682-688. https://doi.org/10.1016/j.mee.2004.12.085
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Gürsel SA, Padeste C, Solak HH, Scherer GG
Microstructured polymer films by X-ray lithographic exposure and grafting
Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions with Materials and Atoms. 2005; 236(1-4): 449-455. https://doi.org/10.1016/j.nimb.2005.04.018
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Schift H, Saxer S, Park S, Padeste C, Pieles U, Gobrecht J
Controlled co-evaporation of silanes for nanoimprint stamps
Nanotechnology. 2005; 16(5): S171-S175. https://doi.org/10.1088/0957-4484/16/5/007
DORA PSI -
Park S, Padeste C, Schift H, Gobrecht J, Scharf T
Chemical nanopatterns via nanoimprint lithography for simultaneous control over azimuthal and polar alignment of liquid crystals
Advanced Materials. 2005; 17(11): 1398-1401. https://doi.org/10.1002/adma.200400989
DORA PSI -
Scharf T, Park S, Padeste C, Schift H, Basturk N, Grupp J
Liquid crystal alignment on chemical nanopatterns: control over azimuthal and polar alignment
Molecular Crystals and Liquid Crystals. 2005; 438: 55/[1619]-65/[1629]. https://doi.org/10.1080/15421400590956054
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Brack H-P, Padeste C, Slaski M, Alkan S, Solak HH
Preparation of micro- and nanopatterns of polymer chains grafted onto flexible polymer substrates
Journal of the American Chemical Society. 2004; 126(4): 1004-1005. https://doi.org/10.1021/ja0379870
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Stamou D, Musil C, Ulrich W-P, Leufgen K, Padeste C, David C, et al.
Site-directed molecular assembly on templates structured with electron-beam lithography
Langmuir. 2004; 20(9): 3495-3497. https://doi.org/10.1021/la049954j
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Padeste C, Steiger B, Grubelnik A, Tiefenauer L
Molecular assembly of redox-conductive ferrocene-streptavidin conjugates - towards bio-electrochemical devices
Biosensors and Bioelectronics. 2004; 20(3): 545-552. https://doi.org/10.1016/j.bios.2004.03.004
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Park S, Schift H, Padeste C, Schnyder B, Kötz Rüdiger, Gobrecht J
Anti-adhesive layers on nickel stamps for nanoimprint lithography
Microelectronic Engineering. 2004; 73-74: 196-201. https://doi.org/10.1016/S0167-9317(04)00098-X
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Padeste C, Solak HH, Brack H-P, Slaski M, Alkan Gürsel S, Scherer GG
Patterned grafting of polymer brushes onto flexible polymer substrates
Journal of Vacuum Science and Technology B: Microelectronics and Nanometer Structures. 2004; 22(6): 3191-3195. https://doi.org/10.1116/1.1805542
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Park S, Padeste C, Schift H, Gobrecht J
Nanostructuring of anti-adhesive layers by hot embossing lithography
Microelectronic Engineering. 2003; 67-68: 252-258. https://doi.org/10.1016/S0167-9317(03)00078-9
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Steiger B, Padeste C, Grubelnik A, Tiefenauer L
Charge transport effects in ferrocene-streptavidin multilayers immobilized on electrode surfaces
Electrochimica Acta. 2003; 48(6): 761-769. https://doi.org/10.1016/S0013-4686(02)00746-6
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Padeste C, Steiger B, Grubelnik A, Tiefenauer L
Redox labelled avidin for enzyme sensor architectures
Biosensors and Bioelectronics. 2003; 19(3): 239-247. https://doi.org/10.1016/S0956-5663(03)00214-8
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Grubelnik A, Padeste C, Tiefenauer L
Highly sensitive enzyme immunoassays for the detection of β-lactam antibiotics
Food and Agricultural Immunology. 2001; 13(3): 161-169. https://doi.org/10.1080/09540100120075817
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Sorribas H, Padeste C, Sonderegger P, Stricker C, Tiefenauer L
Neurochips functionalized with adhesion proteins
European Cells and Materials. 2001; 2(S1): 37-38.
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Sorribas H, Padeste C, Mezzacasa T, Tiefenauer L, Leder L, Fitzli D, et al.
Neurite outgrowth on microstructured surfaces functionalized by a neural adhesion protein
Journal of Materials Science: Materials in Medicine. 1999; 10: 787-791. https://doi.org/10.1023/A:1008955101492
DORA PSI -
Tiefenauer L, Padeste C
Micro-and nanotechnology in biosensor research
Chimia. 1999; 53(3): 62-66.
DORA PSI
Selected earlier Papers
Bio-functional Surfaces and Biosensors
C. Padeste, B. Steiger, A. Grubelnik and L. Tiefenauer, „Molecular Assembly of Redox-Conductive Ferrocene-Streptavidin Conjugates – Towards Bio-Electrochemical Devices”, Biosensors and Bioelectronics 20 (2004) 545-552.
C. Padeste, B. Steiger, A. Grubelnik and L. Tiefenauer, „Redox Labelled Avidin for Enzyme Sensor Architectures“, Biosensors and Bioelectronics, 19 (2003) 239-247.
B. Steiger, C. Padeste, A. Grubelnik and L. Tiefenauer, „Charge Transport Effects in Ferrocene-Streptavidin Multilayers Immobilised on Electrode Surfaces“, Electrochimica Acta, 48 (2003) 761-769.
H. Sorribas, C. Padeste and L. Tiefenauer, „Photolithographic Generation of Protein Micropatterns for Neuron Culture Applications“, Biomaterials 23, 3 (2002) 893-900.
A. Grubelnik, C. Padeste and L. Tiefenauer, „Highly Sensitive Immunoassays for the Detection of β-Lactam Antibiotics“, Food and Agricultural Immunology 13 (2001) 161-169.
C. Padeste, A. Grubelnik and L. Tiefenauer, „Ferrocene-Avidin Conjugates for Bioelectrochemical Applications“, Biosensors and Bioelectronics 15, 9-10 (2000) 431-438.
H. Sorribas, C. Padeste, T. Mezzacasa, L. Tiefenauer, L. Leder, D. Fitzli and P. Sonderegger, „Neurite outgrowth on microstructured surfaces functionalized by a neural adhesion protein“, J. Mat. Sci, Mat. in Medicine, 10 (1999) 787-791.
R. Ros, F. Schwesinger, C. Padeste, A. Plückthun, D. Anselmetti, H.-J. Güntherodt and L. Tiefenauer, „SPM for Functional Identification of Individual Biomolecules“, Proc. SPIE 3607 (1999) 84-89.
L. Tiefenauer and C. Padeste, „Micro- and Nanotechnology in Biosensor Research“, Chimia 53, 3 (1999) 62-65.
C. Padeste, A. Grubelnik and L. Tiefenauer, „Amperometric Immunosensing using Microperoxidase MP‑11 Antibody Conjugates“, Anal. Chim. Acta., 374 (1998) 167-176.
V. von Reding, C. Padeste, J. Spichiger, A. Grubelnik and L. Tiefenauer, „Testsystem für amperometrische Immunosensoren“, Bioworld 4/98 (1998) 30-32.
S. Kossek, C. Padeste, L.X. Tiefenauer and H. Siegenthaler, „Localization of Individual Biomolecules on Sensor Surfaces“, Biosensors & Bioelectronics, 13, 1 (1998) 31-43.
L.X. Tiefenauer, S. Kossek, C. Padeste and P. Thiébaud, „Towards Amperometric Immunosensor Devices“, Biosensors & Bioelectronics 12, 3 (1997) 213-223.
C. Padeste, S. Kossek, H.W. Lehmann, C.R. Musil, J. Gobrecht and L. Tiefenauer, „Fabrication and Characterization of Nanostructured Gold Electrodes for Electrochemical Biosensors“ J. Electrochemical Soc., 143, 12 (1996) 3890-3895.
S. Kossek, C. Padeste and L. Tiefenauer, „Immobilization of Streptavidin for Immunosensors on Nanostructured Surfaces“, J. Mol. Recogn. 9 (1996) 485-487.
C. Padeste, S. Kossek and L. Tiefenauer, „Modular Amperometric Immunosensor Devices“ Digest of Technical Papers of Transducers ‘95/Eurosensors IX, Stockholm, 1995, p.487-490.
(Nano)-Structuring and Surface Functionalization
S. Park, H. Schift, C. Padeste, B. Schnyder, R. Kötz and J. Gobrecht, „Anti-adhesive Layers on Nickel Stamps for Nanoimprint Lithography”, Microelectronic Engineering, 73-74 (2004) 196-201.
H. H. Solak, C. Padeste, J. Gobrecht, „Patterning of Surfaces with X-ray Interference Lithography at Macromolecular Length Scales“, European Cells and Materials 6, Suppl. 1 (2003) 71.
S. Park, C. Padeste, H. Schift and Jens Gobrecht, „Nanostructuring of Anti-adhesive Layers by Hot Embossing Lithography“, Microelectronic Engineering, 67-68 (2003) 252-258.
H. Schift, L.J. Heyderman, C. Padeste and J. Gobrecht, „Chemical Nano-Patterning using Hot Embossing Lithography“, Microelectronic Engineering, 61-62 (2002) 423-428.
Surface Science and Catalysis
D.L. Trimm, C. Padeste, D.J. Pettigrew, B.Whittington and N.W. Cant, “Precious Metal-Ceria interactions in Car Exhaust Catalysts“, in R.J. MacDonald, E.C. Taglauer, K.R. Wandelt (Eds.), „Surface Science, Principles and Current Applications“, Springer, Heidelberg (1996) pp. 363-372.
C. Padeste, N.W. Cant and D.L. Trimm, „Reactions of Ceria Supported Rhodium with Hydrogen and Nitric Oxide Studied with TPR/TPO and XPS techniques“, Catal. Lett. 28 (1994) 301-311.
F. Mohammadi, P. Timbrell, S. Zhong, C. Padeste and M. Skyllas-Kazakos, „Overcharge in the Vanadium Redox Battery and Changes in Electrical Resistivity and Surface Functionality of Graphite-Felt Electrodes“ J. Power Sources, 52 (1994) 61-68.
C. Padeste, N.W. Cant and D.L. Trimm, „Thermal Decomposition of Pure and Rhodium Impregnated Cerium (III) Carbonate Hydrate in Different Atmospheres“, Catal. Lett. 24 (1994) 95-105.
S. Zhong, C. Padeste, M. Kazacos and M. Skyllas-Kazacos, „Comparison of the Physical, Chemical and Electrochemical Properties of Rayon- and Polyacrylonitrile-Based Graphite Felt Electrodes“, J. Power Sources, 45 (1993) 29-41.
C. Padeste, N.W. Cant and D. L. Trimm, „The Influence of Water on the Reduction and Reoxidation of Ceria“, Catal. Lett. 18 (1993) 305-316.
C. Padeste, D.L. Trimm and R.N. Lamb, „Characterization of Sn Doped Ni/Al2O2 Steam Reforming Catalysts by XPS“, Catal. Lett., 17 (1993) 333-339.
Solid State Chemistry
C. Padeste, H. Schmalle and H.R. Oswald, „Crystal Structure of Calcium Hydroxide Nitrate Hydrate and its Superstructure in Relation to Cadmium Hydroxide Nitrate Hydrate”, Z. Krist. 200 (1992) 35-96.
C. Padeste, A. Reller and H.R. Oswald, „The Thermal Behaviour of Pure and Nickel-Doped Hydromagnesite in Different Atmospheres“, Mat. Res. Bull. 26, 12 (1991) 1263-1268.
A. Reller, R. Emmenegger, C. Padeste and H.R. Oswald, „Thermochemical Reactivity of Metal Carbonates“, Chimia 45 (1991) 262-266.
C. Padeste, A. Reller and H.R. Oswald, „The Influence of Transition Metals on the Thermal Decomposition of Calcium Carbonate in Hydrogen“, Mat. Res. Bull. 25 (1990) 1299-1305.
A. Reller, H. Maurer and C. Padeste, „The Use of Solar Energy for the Generation of Organic Carbon Compounds from Natural Metal Carbonates and for the Thermochemical Reduction of Metal Oxides“, Proc. 4th Int. Symp. on Research, Development and Applications of Solar Thermal Technology, Hemisphere Publishing Corporation, New York, Washington, Philadelphia, London, 1990, p. 407.
A. Reller, C. Padeste and P. Hug, „Formation of Organic Compounds from Metal Carbonates“, Nature, 239 (1987) 527.
Short CV
Education
- Diploma in Chemistry and PhD in inorganic solid state chemistry, University of Zürich, Switzerland
- Post-Doc in surface science of catalysts, University of New South Wales, Sydney, Australia
Employment At PSI / LMN since August 1993
1993-2003: Molecular Nanotechnology
- surface design
- surface modification
- protein immobilization
- electrochemical detection of labelled proteins
2003-2019: Nanofabrication Technologies / Polymer Nanotechnology
- polymer micro- and nanografting
- x-ray interference lithography (XIL)
- creation of protein patterns and chemical nanopatterns
- supports for serial crystallography
Since 2020: Member of the Mechanogenomics Group, Lab for Nanoscale Biology
- supports for serial crystallography at XFELs and synchrotron beamlines
- micro and nanofabrication for bio applications