Research on Covid-19

At PSI, several projects are dedicated to important research questions concerning the Sars-CoV-2 coronavirus and the resulting diseases. We provide information on activities and projects, for example on investigations of lung tissue, on the production of proteins and antibodies or on ideas for new research on Covid-19.

Useful links

Lattanzi et al

Amyloid β 42 fibril structure based on small-angle scattering

Alzheimers disease is one of the major global health challenges. Neuronal cell dysfunction and death are connected to the self-assembly of the amyloid β peptide (Aβ42) into oligomeric and fibrillar aggregates. The fibril surface can catalyze the formation of toxic oligomers via secondary nucleation.

 

SNI

LMN PhD student Martin Heinrich wins poster award

PhD student Martin Heinrich of the Molecular Nanoscience group won the best poster award at the Nano-BW 2021 symposium at Bad Herrenalb (Germany), October 6-7. The symposium is held annually within the research network “Functional Nanostructures” of Baden-Württemberg.

Martin introduced his project in the form of a poster titled “Local Manipulation of Spin Domains in a Multiferroic Rashba Semiconductor”. His project started in July 2021 and is funded by the Swiss Nanoscience Institute (SNI) Basel. The poster award was selected by the vote of all attendees.

2021 Zukunftstag

Zukunftstag 2021

Am Donnerstag, 11. November haben 99 Kinder am Nationalen Zukunftstag des PSI teilgenommen. 51 Mädchen durften am Vormittag und 48 Jungs am Nachmittag 2 Stationen aus 14 Möglichen besuchen. Danke an alle engagierten Helferinnen und Helfer!

Das et al

Unconventional Pressure Dependence of the Superfluid Density in the Nodeless Topological Superconductor α-PdBi2

We investigated the superconducting properties of the topological superconductor α-PdBi2 at ambient and external pressures up to 1.77 GPa using muon spin rotation experiments. The ambient pressure measurements evince a fully gapped s-wave superconducting state in the bulk of the specimen. Alternating current magnetic susceptibility and muon spin rotation measurements manifest a continuous suppression of Tc with increasing pressure.

 

EPFL - Digitaltag

Interesting Article Published: More Young Women in STEM - But How?

Read the interesting report on Sciena.ch about what the ETH Domain is doing to increase the proportion of women in STEM subjects and to motivate young girls in particular to take up these professions.

Keyence optical 3D Profiler

New Confocal Microscope Keyence VK-X3100

Keyence VK-X3100 is a  non-contact 3D surface profiler. It enables capturing images and performing the profile, roughness and film thickness analysis. The measurement head is equipped with semiconductor laser with the wave length of 404 nm and white LED. To reach the best performance, it uses laser confocal scanning, focus variation, adn while light interferometry  measurement methods. The motorized sample stage allows for automatic inspection of up to 200mm wafers.

LeLa 2001

LeLa 2021 am PSI "100 Lernende waren im Einsatz"

Vom 19. Oktober – 03. November 2021 fand das LeLa 2021 am PSI statt. An 10 Arbeitstagen wurden  ver-schiedene Arbeiten am PSI und in den Gemeinden Würenlingen und Villigen von den Lernenden durchgeführt.

Yang_H_Diss_Ammann_M

Congratulations to Huanyu Yang

On 10th November 2021 Huanyu Yang successfully defended his PhD entitled “Hydrogen Bonding structure of Water at Interfaces relevant for ice nucleation" at ETH Zürich. 

Picture: Huanyu Yang with supervisor Markus Ammann.

 

Ammonium sulfate has been used as a probe for aerosol particles and investigated in situ by means of ambient pressure X-ray photoelectron spectroscopy. Unexpectedly, when the particles start to absorb water, a spontaneous redox reaction leading to nitrogen and elemental sulfur takes place.

PUBLISHED IN SCIENCE: A surface-promoted redox reaction occurs spontaneously on solvating inorganic aerosol surfaces

Ammonium sulfate has been used as a probe for aerosol particles and investigated in situ by means of ambient pressure X-ray photoelectron spectroscopy. Unexpectedly, when the particles start to absorb water, a spontaneous redox reaction leading to nitrogen and elemental sulfur takes place.

Retina

Neurodegenerative disease studied by cryogenic X-ray nanotomography

Hard X-ray cryo-tomography scanning of retina from healthy and inherited blindness specimen paves the way for correlative analysis after imaging at the cSAXS beamline.

Lithium Fluoride on Ag(100): Dendrites vs. Islands

Vastly Different Morphologies Dependent on the Growth Temperature

Lithium fluoride is an important material which is technologically exploited in spintronics and organic light emitting devices. It turns out that there is a vast difference between the morphologies of ultrathin lithium fluoride grown on the (100) facet of a silver single crystal.  At room temperature dendrites are obtained while at elevated temperature lithium fluoride forms square islands. The system is an interesting model to study the crossover between diffusion limited aggregates and island growth.

diamond_grantings_teaser

Diamond gratings for XFEL amplitude-splitting delay line

A split-and-delay line for XFEL pulses has been built and successfully tested by a team of researchers at the Linac Coherent Light Source. Key X-ray optical elements are two diamond diffraction gratings made at the Paul Scherrer Institut that are used to split and later recombine the intense ultrashort X-ray laser pulses for time-resolved measurements.

Ioannis Paraskevas

Ioannis Paraskevas successfully defends his Ph.D. thesis on Mu3e commissioning

Ioannis Paraskevas commissioned the solenoid magnet and Mu3e beamline, developing simulations and carrying out measurements prior to the first Mu3e integration run. He also performed a study of fake tracks in simulation. He successfully defended his thesis during a virtual viva at University College London. Congratulations!

Meseguer et al

Coexistence of structural and magnetic phases in van der Waals magnet CrI3

CrI3 has raised as an important system to the emergent field of two-dimensional van der Waals magnetic materials. However, it is still unclear why CrI3 which has a ferromagnetic rhombohedral structure in bulk, changed to anti-ferromagnetic monoclinic at thin layers. Here we show that this behaviour is due to the coexistence of both monoclinic and rhombohedral crystal phases followed by three magnetic transitions at TC1 = 61 K, TC2 = 50 K and TC3 = 25 K.

 

Besuch ILMAC 2021

Besuch der ILMAC 2021

Kurzer Elebnisbericht eines Laboranten Chemie vom Besuch an der Chemiemesse ILMAC in Basel am 20. Oktober 2021.

dual-photocathode laser capabilities and perspectives for exotic FEL modes

Overview of SwissFEL dual-photocathode laser capabilities and perspectives for exotic FEL modes

SwissFEL is a compact, high-brilliance, soft and hard X-ray Free Electron Laser (FEL) facility laser composed of two parallel beam lines seeded by a common linear accelerator (LINAC), and a two-bunch photo-injector. For the injector, an innovative dual-photocathode laser scheme has been developed based on state-of-the-art Ytterbium femtosecond laser systems. We just published an overview of the the SwissFEL Photo Cathode Drive Lasers (PCDL) performance, pulse shaping capabilities as well as the versatility of the systems, which allow many different modes of operation of SwissFEL [1]. The full control over the SwissFEL electron bunch properties via the unique architecture of the PCDL will enable in the future the advent of more advanced FEL modes; these modes are, but not restricted to, the generation of single or trains of sub-fs FEL pulses, multi-color FEL and finally the generation of fully coherent X-ray pulses via laser-based seeding.

Spatially resolved likelihood for glycation of collagen

Glycation of collagen: Quantifying rates

Collagen is abundant in the connective tissue of human beings, e.g. in tendons, ligament and cornea. Glycation of collagen distorts its structure, renders the extracellular matrix stiff and brittle and at the same time lowers the degradation susceptibility thereby preventing renewal. Based on models and with parameters determined from experimental data, we describe the glycation of type 1 collagen in bovine pericardium derived bio-tissues upon incubation in glucose and ribose. We hope that this contributes to a better quantitative understanding of the effects of diabetes on collagen.

Artist's view of the functionalized endohedral fullerene on a graphite surface.

Magnetic Bistability at a Record High Temperature in a Sub-Monolayer of Endohedral Fullerenes

A team of the Leibniz Institute for Solid State Research (IFW) from Dresden, Germany, led by Dr Alexey Popov has now demonstrated a record blocking temperature of 28 Kelvin at which the magnetic bistability still survives in a submonolayer of a chemically functionalized species of endofullerenes. In this research, X-ray magnetic circular dichroism measurements at low temperatures and high magnetic field at the X-Treme beam line are crucial. The results pave the way toward using such single-molecule magnets as information carriers or magnetic bits.