Au PSI, plusieurs projets se consacrent à des questions de recherche importantes autour du coronavirus Sars-CoV-2 et des maladies qui en résultent. Nous vous informons sur les activités et les projets, par exemple sur les analyses de tissus pulmonaires, sur la production de protéines et d'anticorps ou sur les idées de nouvelles recherches sur le Covid-19.
Liens utils
GFA delivers the SwissFEL magnets on schedule
The Paul Scherrer Institut is building an X-ray free electron laser (SwissFEL) providing a source of intense, ultra-short pulses of coherent radiation in the wavelength range of 0.1 nm to 0.7nm. For the hard X-ray beam line, the magnet section in GFA/ATK has the responsibility for the design, the procurement and the magnetic qualification of 267 electro-magnets of 22 different types. Several design studies were performed in an attempt to meet the required magnet specifications while optimizing construction and operation cost.
Biophysical effects of UV radiation on biological samples
The biological influence of radiation on living matter has been studied for years; however, several questions about the detailed mechanism of radiation damage formation remain largely unanswered. Among all biomolecules exposed to radiation, DNA plays an important role because any damage to its molecular structure can affect the whole cell and may lead to chromosomal rearrangements resulting in genomic instability or cell death.
Ralentissement du flux électrique peut montrer la voie vers des ordinateurs économes en énergie
Les ordinateurs et les autres appareils électroniques représentent aujourd’hui une part considérable de la consommation d’énergie, une part dont il est pratiquement impossible de modifier l’importance avec les technologies actuellement utilisées. Les puces électroniques qui prendront place dans les appareils économes en énergie de demain devront donc être composées de matériaux innovants. De nouveaux résultats de recherche indiquent une voie possible comment on peut obtenir ces matériaux.
Transport of first "completed" Undulator into the SwissFEL Tunnel
On the 25th of January, the first "completed" undulator has been transported to its final position in the SwissFEL tunnel. The 1064 permanent magnets of this undulator where shimmed to the sub-micrometer level and the magnetic profile has been carefully measured for the full gap range. Twelve of such undulators will be installed until October 2016!
Small-Angle Neutron Scattering Study of Interplay of Attractive and Repulsive Interactions in Nanoparticle-Polymer System
The phase behavior of nanoparticle (silica)−polymer (polyethylene glycol) system without and with an electrolyte (NaCl) has been studied. It is observed that nanoparticle−polymer system behaves very differently in the presence of electrolyte. In the absence of electrolyte, the nanoparticle−polymer system remains in one-phase even at very high polymer concentrations.
Georgian Order of Honor for Zurab Guguchia
Thomas Prokscha from Laboratory for the Muon Spin Spectroscopy LMU and Head of the LEM Group was invited to serve an additional year as a member of the INTC Committee (ISOLDE and Neutron Time-of-Flight Experiments Committee) at CERN.
The INTC evaluates proposals for experiments on the ISOLDE facility. In addition it reviews the experiments proposed for the neutron time-of-flight facility.
Reconduction des directeurs du PSI et du WSL
Sur proposition du Conseil des EPF, le Conseil fédéral a reconduit dans leurs fonctions, le 20 janvier 2016, Joël Mesot, directeur de l’Institut Paul Scherrer PSI, et Konrad Steffen, directeur de l’Institut fédéral de recherches sur la forêt, la neige et le paysage WSL, pour une période de quatre ans. Joël Mesot entamera son troisième mandat le 1er août 2016 et Konrad Steffen son deuxième mandat le 1er juillet 2016.
Mechanically Enhanced Liquid Interfaces at Human Body Temperature Using Thermosensitive Methylated Nanocrystalline Cellulose
The mechanical performance of materials at oil/water interfaces after consumption is a key factor affecting hydrophobic drug release. In this study, we methylated the surface of nanocrystalline cellulose (NCC) by mercerization and dimethyl sulfate exposure to produce thermosensitive biopolymers. These methylated NCC (metNCC) were used to investigate interfacial thermogelation at air/water and medium-chain triglyceride (MCT)/water interfaces at body temperature.
Controlling tunnelling in methane loss from acetone ions by deuteration
If a ball is rolled up a hill with less kinetic energy than the potential energy at the top, it will return eventually, and stays bound in the valley. Tunnelling is a distinctly quantum mechanical phenomenon, in which such balls can magically cross the hill, and appear in the neighbouring valley, as if going through a tunnel. In order for this to happen with a non-negligible probability, the ball has to be small and the barrier, i.e. the hill, sharp.
Attaquer le cancer de manière ciblée
Il existe des tumeurs contre lesquelles, apparemment, rien ne marche: ni la chimiothérapie, ni la radiothérapie externe, ni la chirurgie. Souvent, elles ont déjà formé des métastases et ne peuvent plus être éliminées par des méthodes conventionnelles. La seule issue qui reste alors, c’est la radiothérapie interne avec des substances radioactives ciblées, que l’on introduit directement dans la tumeur. Vingt chercheurs spécialisés œuvrent dans ce but au Centre des sciences radiopharmaceutiques à l’Institut Paul Scherrer PSI, une institution commune du PSI, de l’EPF Zurich et de l’Hôpital universitaire de Zurich.
Self-Diffusion in Amorphous Silicon
The present Letter reports on self-diffusion in amorphous silicon. Experiments were done on 29Si/natSi heterostructures using neutron reflectometry and secondary ion mass spectrometry. The diffusivities follow the Arrhenius law in the temperature range between 550 and 700°C with an activation energy of (4.4 ± 0.3) eV.
Des neutrons mettent en évidence la répartition d’îlots de tubes de flux
Normalement, les supraconducteurs repoussent les champs magnétiques appliqués. Mais à l’intérieur des supraconducteurs de type II, il se forme de fins canaux appelés tubes de flux par lesquels passe le champ magnétique, alors que le reste du matériau reste sans champ et supraconducteur. Dans le niobium (un métal), les tubes de flux se regroupent en îlots et forment des schémas complexes, que l’on rencontre fréquemment dans la nature sous une forme analogue. Des chercheurs du PSI et de l’Université technique de Munich (Technische Universität München: TUM) sont les premiers à avoir mené des expériences avec des neutrons pour analyser ces structures dans le niobium. Ils ont réussi à visualiser en détail la répartition des îlots.
First ultraprecise mirror for SwissFEL arrived at PSI
Mirrors are key elements to distribute and shape the Xray beam generated by the undulators of the SwissFEL facility. They are essential tools to guide and focus the light according to the specific users requirements and should do this without noticeable effects on the beam quality. A quantitative measure is the quality of the beam wavefront. The wavefront must be conserved by the optical elements in the SwissFEL beamlines within a fraction of the wavelength which can be as short as one Angstrom in the case of Aramis. There are only few companies in the world, who are able to fabricated such ultraprecise mirrors.
In-situ visualization of stress-dependent bulk magnetic domain formation by neutron grating interferometry
The performance and degree of efficiency of industrial transformers are directly influenced by the magnetic properties of high-permeability steel laminations (HPSLs). Industrial transformer cores are built of stacks of single HPSLs. While the insulating coating on each HPSL reduces eddy-current losses in the transformer core, the coating also induces favorable inter-granular tensile stresses that significantly influence the underlying magnetic domain structure.
First ultraprecise mirror for SwissFEL arrived at PSI
Mirrors are key elements to distribute and shape the Xray beam generated by the undulators of the SwissFEL facility. They are essential tools to guide and focus the light according to the specific users requirements and should do this without noticeable effects on the beam quality. A quantitative measure is the quality of the beam wavefront.
Endlagersuche: Viele 100'000 Jahre sicher im Ton
Obwohl die Schweiz aus der Kernenergie aussteigt, muss sie eine Lösung für das in den Kernkraftwerken, aber auch in Medizin, Industrie und Forschung entstandene, radioaktive Material finden. Daher stellt sie sich einer aussergewöhnlichen, verantwortungsvollen Aufgabe: Sie sucht einen Ort, an dem sie ihre radioaktiven Abfälle mehrere hunderttausend Jahre lang sicher lagern kann. So lange, bis sie von selbst die Radioaktivität natürlicher Gesteine erreicht haben.
Rate of Molecular Transfer of Allyl Alcohol across an AOT Surfactant Layer Using Muon Spin Spectroscopy
The transfer rate of a probe molecule across the interfacial layer of a water-in-oil (w/o) microemulsion was investigated using a combination of transverse field muon spin rotation (TF-μSR), avoided level crossing muon spin resonance (ALC-μSR), and Monte Carlo simulations. Reverse micro-emulsions consist of nanometer-sized water droplets dispersed in an apolar solvent separated by a surfactant monolayer.
Determining the structures of nanocrystalline pharmaceuticals by electron diffraction
A new type of detector developed by Dr. van Genderen enables the structure determination of pharmaceutical compounds with electron diffraction at room temperature. The group concentrate on expanding this new technique to macromolecular compounds.
En route pour le tunnel du faisceau
Depuis l’automne 2015, le tunnel du faisceau du nouveau grand instrument de recherche du PSI se remplit de composants mécaniques. L’un après l’autre, les composants prémontés sont acheminés à leur emplacement définitif.
Mass density distribution of intact cell ultrastructure
The determination of the mass density of cellular compartments is one of the many analytical tools that biologists need to unravel the extremely complex structure of biological systems. Cryo X-ray nanotomography reveals absolute mass density maps of frozen hydrated cells in three dimensions.
Preserved Embryos Illustrate Seed Dormancy in Early Angiosperms
The discovery of exceptionally well-preserved, tiny fossil seeds dating back to the Early Cretaceous corroborates that flowering plants were small opportunistic colonizers at that time, according to a new Yale-led study.
Mesurer la simultanéité
Que fait un physicien lorsque son expérience nécessite un chronométrage d’une extrême précision? D’une précision telle que l’électronique existante n’est pratiquement d’aucun secours? Un chercheur de l’Institut Paul Scherrer PSI a décidé sans autre forme de procès de développer lui-même une solution: sa puce électronique de haute précision, baptisée DRS4, pourrait bien permettre de déchiffrer les lois physiques qui gouvernent notre univers tout entier. Incidemment, elle permet aujourd’hui déjà aux médecins de localiser des tumeurs cérébrales de manière extrêmement précise.
Tunable spin polarization and superconductivity in engineered oxide interfaces
A new kind of 2DEG is found by inserting two atomic layers of the antiferromagnetic and insulating compound EuTiO3 between LaAlO3 and SrTiO3. The 2DEG is found to exhibit besides a superconducting ground state, a strong spin-polarization. The magnetism of Eu and Ti was studied by XMCD at the X-Treme beamline in SLS.
Kohlendioxid: Das Klimaproblem im Untergrund entsorgen?
Allen Warnungen vor den Folgen des Klimawandels zum Trotz und unbeeindruckt von politischen Absichtserklärungen: Die weltweiten Kohlendioxidemissionen steigen und steigen. Hauptverantwortlich dafür sind Kohle- und Gaskraftwerke, die den zunehmenden Strombedarf decken. Könnte man deren Kohlendioxidemissionen dauerhaft im Boden speichern, anstatt damit Atmosphäre und Klima zu belasten? Und wäre das auch für die Schweiz interessant? Diese Fragen beleuchtet der neueste Energie-Spiegel des PSI.Cette actualité n'existe qu'en allemand.
First EIGER X 16M in operation at the Swiss Light Source
The macromolecular crystallography beamline X06SA at the Swiss Light Source, a synchrotron operated by Paul Scherrer Institute, is the first one in the world to upgrade its detector to an EIGER X 16M.
The flip-over effect in pulsed laser deposition: Is it relevant at high background gas pressures?
In pulsed laser deposition the use of a rectangular or elliptical beam spot with a non 1:1 aspect ratio leads to the so called flip-over effect. Here, the longest dimension of the laser spot results in the shortest direction of plasma plume expansion.
Controlling tunnelling in methane loss from acetone ions by deuteration
If a ball is rolled up a hill with less kinetic energy than the potential energy at the top, it will return eventually, and stays bound in the valley. Tunnelling is a distinctly quantum mechanical phenomenon, in which such balls can magically cross the hill, and appear in the neighbouring valley, as if going through a tunnel. In order for this to happen with a non-negligible probability, the ball has to be small and the barrier, i.e. the hill, sharp.
La nanostructure d’un os dévoilée en 3D
Les os sont composés de minuscules fibres, à peu près mille fois plus fines qu’un cheveu humain. Avec un nouveau type de méthode d’analyse informatique des chercheurs de l'Institut Paul Scherrer PSI étaient en mesure de déterminer pour la première fois l’agencement local et l’orientation de la nanostructure à l’intérieur d’un fragment d’os.
Nanostructure surveys of macroscopic specimens by small-angle scattering tensor tomography
The mechanical properties of many materials are based on the macroscopic arrangement and orientation of their nanostructure. This nanostructure can be ordered over a range of length scales. In biology, the principle of hierarchical ordering is often used to maximize functionality, such as strength and robustness of the material, while minimizing weight and energy cost.
Aluminium X-ray absorption near-edge spectroscopy analysis of discoloured ultramarine blue in 20th century oil paintings
A specific case of synthetic ultramarine degradation was observed in three oil paintings from the early 20th century. Pigment particleswere found to have been discoloured, resulting in intricate patterns ofwhite lines, approximately 10 to 30 microns wide, criss-crossing the paint surface. Colour in ultramarine pigments comes from the encapsulated sulphur radical anions, chromophores, inside the cage framework built from SiO4 4 − and AlO4 5 −